Mild cognitive impairment (MCI) represents a transitional state between normal aging and dementia. 4 key findings →
Evidence: low
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Research
28,180 Alzheimer's and dementia studies in plain English, each scored out of 100.
Environmental Burden Rank (EBR) across the sample (0.53±0.32) was near the 50th percentile nationally. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
is a heuristic that seeks to develop methodologies capable of identifying subtle behavior(s) that may flag emerging AD and other dementia related syndromes. 2 key findings →
Evidence: low
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The results showed that Age, Education, and, occasionally, Biological sex were significant predictors. 5 key findings →
Evidence: low
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Overall, the combined features model achieved a higher discrimination accuracy than models with single feature sets alone. 5 key findings →
Participants: 128 Evidence: low
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Early detection of abnormal neurodegeneration amidst normal cognitive aging is crucial. 1 key finding →
Design: cross-sectional Evidence: moderate
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41/100
RoCA classifies patients similarly to gold standard paper-based tests, with a receiver operating characteristic area under the curve of 0.81 (95% CI 0.67-0.91; P<.001). 5 key findings →
Design: open-label trial Participants: 35 Evidence: low
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The MMSE-2 demonstrated robust performance in differentiating participants across Clinical Dementia Rating (CDR) stages and CDR-Sum of Boxes scores. 5 key findings →
Participants: 66 Evidence: low
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Mild cognitive impairment (MCI) represents a heterogeneous state between normal aging and dementia, with varied transition pathways. 3 key findings →
Participants: 272 Evidence: low
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The presented results suggest the suitability of ecological handwriting analysis for the all-around monitoring of MCI, from early screening to disease progression evaluation. 4 key findings →
Participants: 57 Evidence: low
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MAP-RTAP (AUC = 0.78) and pTau/Aβ42 (AUC = 0.76) were the best performing individual biomarkers. 4 key findings →
Evidence: low
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Among the atrophic brain regions in aMCI, VSTM performance correlated with the volume of the right prefrontal cortex (PFC) but not the medial temporal lobe (MTL), and this correlation was mainly present in patients with greater MTL atrophy. 5 key findings →
Evidence: low
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Our results showed that: (a) Behavioral data analysis: there were significant differences in accuracy and accuracy / reaction time between MCI and NC in tasks with memory load capacity of low load-four and high load-six, especially in tasks with memory load capacity of four. 5 key findings →
Evidence: low
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Underreporters showed lower cognitive performance (p = 0.021), which did not translate into higher self-report SMC (p = 0.092). 3 key findings →
Design: longitudinal study Evidence: moderate
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Alzheimer’s disease (AD) presents significant challenges in clinical practice due to its heterogeneous manifestation and variable progression rates. 3 key findings →
Participants: 504 Evidence: low
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EMCIs and LMCIs, especially LMCIs, exhibited poorer performance in almost all global and multidimensional cognitive tests. 5 key findings →
Participants: 35 Evidence: low
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demonstrated high goodness of fit and satisfied all validation metrics. 5 key findings →
Evidence: low
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Of the 747 studies identified, 6 studies fulfilled the eligibility criterion for this review. 4 key findings →
Evidence: high
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Emotion scores for fear and surprise were significantly higher for the AD group than for the MCI group during dual tasks (p=0.016), while emotion scores for joy were significantly higher for the MCI group than for the AD group during creative activities (p=0.012). 4 key findings →
Participants: 14 Evidence: low
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Synaptic disruption is an early pathological sign of the neurodegeneration of Dementia of the Alzheimer's type (DAT). 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Participants included 10 physiatrists, 6 OTs, and 11 patients with mild cognitive impairment and mild dementia. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Test-retest reliability data of the Arabic MoCA were collected approximately 35.0 +/- 17.6 days apart. 2 key findings →
Evidence: low
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Over 78 million people will suffer from dementia by 2030, emphasizing the need for early identification of patients with mild cognitive impairment (MCI) at risk, and personalized clinical evaluation steps to diagnose potentially reversible causes. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
The distribution of scores in the Mini Mental State Examination (MMSE) of women aged 70-79 years from a rural area of Cambridgeshire is reported. 2 key findings →
Evidence: low
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PVTs provide valuable information regarding response bias and, under the right circumstances, can provide excellent evidence of response bias. 1 key finding →
Evidence: low
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From across this tag
10 of the 850 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
- Prevalence, distribution, and impact of mild cognitive impairment in Latin America, China, and India: a 10/66 population-based study
- Mapping progressive brain structural changes in early Alzheimer's disease and mild cognitive impairment
- Mini-Mental State Examination (MMSE) for the detection of Alzheimer's disease and other dementias in people with mild cognitive impairment (MCI)
- Impact of SSRI Therapy on Risk of Conversion From Mild Cognitive Impairment to Alzheimer's Dementia in Individuals With Previous Depression
- Evaluating the Feasibility of Frequent Cognitive Assessment Using the Mezurio Smartphone App: Observational and Interview Study in Adults With Elevated Dementia Risk
- Prevalence and correlates of the head turning sign in mild cognitive impairment and dementia due to neurodegenerative, chronic cerebrovascular, and mixed etiologies
- Olfactory cortex degeneration in Alzheimer's disease and mild cognitive impairment
- Genetic background and multidomain interventions in mild cognitive impairment
- Digital Biomarkers for the Early Detection of Mild Cognitive Impairment: Artificial Intelligence Meets Virtual Reality
- Conventional and neuropsychological criteria for mild cognitive impairment show similar prognostic value for dementia across 12 years in a non-clinical setting
Where “Free full text” comes from
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
How the 0–100 score works — and why some entries are capped
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
- Journal tier up to 10 pts
- Journal's citation record up to 4 pts
- Study design up to 12 pts
- Strength of evidence up to 5 pts
- Peer-review validation up to 10 pts
- How recent up to 5 pts
- Sample size up to 4 pts
- Effect reported up to 3 pts
- Studied in people up to 3 pts
- Randomised / blinded up to 2 pts
- Times cited up to 7 pts
- Citations per year up to 5 pts
- Impact for its field and year up to 6 pts
- Cited by studies here up to 6 pts
- Still being cited up to 4 pts
- Senior author's track record up to 4 pts
- Institution's track record up to 3 pts
- Multi-centre collaboration up to 3 pts
- Indexed in PubMed up to 2 pts
- Free to read up to 2 pts
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 28,180 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
What this library is — and isn't
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 28,180 records, built mostly from automated pulls of Europe PMC (61.7% of the library) and OpenAlex (18.1%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →