30,980 Alzheimer's and dementia studies in plain English, each scored out of 100.
Four main themes were identified: (1) reasons family caregivers may not choose formal care, (2) perceived benefits of formal care, (3) how family caregivers choose formal care, and (4) recommendations for delivering information about formal care options. 5 key findings →
Evidence: low
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Beyond these practical challenges, caregivers often endure significant physical exhaustion and sleep deprivation from the unrelenting demands of caregiving, which can lead to chronic fatigue and deteriorating health (Liu et al., 2022; Mao et al., 2024). 5 key findings →
Evidence: low
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I consider applications of “AI extenders” to dementia care. 1 key finding →
Evidence: low
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The Tailored Activity Program (TAP), an intervention for people living with dementia (PLWD) and their caregivers, has been shown to reduce behavioral symptoms for PLWD and caregiver burden. 5 key findings →
Evidence: low
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Our analysis revealed a diverse range of topics reflecting community members' varying needs and concerns of individuals affected by AD/ADRD. 5 key findings →
Evidence: low
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Participants found MATCH acceptable (combined AES median score of 28, range 25-34) and useful (SUS median score of 73.5, range 55-100). 5 key findings →
Evidence: low
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After a 30-minute educational session, participants showed greater positivity toward an ADRD diagnosis and increased confidence in discussing early detection. 5 key findings →
Participants: 25 Evidence: low
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Black participants had low (vs high) OP, which predicted worse episodic memory and global cognition (4% to 7% mediated). 5 key findings →
Evidence: low
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Key reflections from advisor meetings guided cultural adaptation: lived experiences on dementia caregiving; patient, caregiver, and clinician interactions in the health care system; and limited knowledge and misconceptions of palliative care. 4 key findings →
Evidence: low
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Four major themes emerged: Unfolding Process of ADRD Discovery , Resilience is Multifaceted in Caregiving , Resilience is an Adaptive Process , and Cultural Heritage Shapes Caregivers' Resilience Experiences . 1 key finding →
Participants: 18 Evidence: low
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Twenty-eight caregivers completed the intervention, which increased caregiver mastery and decreased stress and burden. 5 key findings →
Design: open-label trial Evidence: low
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From 1990 to 2021, the incidence, prevalence, and DALYs of ADOD have significantly risen both globally and in China, with the growth rates in China notably surpassing the global average. 5 key findings →
Evidence: moderate
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Significant differences in 64% of engagement-related behaviors were found between groups, notably in torso movements, voice modulation, facial expressions, and concentration. 5 key findings →
Participants: 15 Evidence: low
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So far, we included 42 patients in our study, that were monitored for at least 7 consecutive days and nights, to form the largest database of its kind in the world. 5 key findings →
Participants: 42 Evidence: low
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AD patients exhibited a significantly higher prevalence of APOE e3/e4 and e4/e4 genotypes compared to DLB and HC (p <0.001). 5 key findings →
Evidence: low
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Informed consent is a critical ethical requirement in research, ensuring the protection of participants' rights and promoting their wellbeing and autonomy. 5 key findings →
Evidence: low
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The calibration models for photopic lux and correlated color temperature demonstrated strong accuracy, with an adjusted R² of 0.858 and 0.982, respectively, ensuring reliable sensor measurements. 5 key findings →
Evidence: low
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Significant predictive performance was observed for several neurocognitive disorders. 5 key findings →
Evidence: low
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The attributes of concepts of social frailty and social isolation overlap, including being alone and having limited or less social activities, engagements or interactions. 5 key findings →
Evidence: low
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< .01). All patient groups were also impaired on AVLT encoding, TMT-B and TMT B/A. Social and non-social neurocognitive functions differed between groups, with specific impairments in processing speed in VaD, emotion recognition in bv-FTD and memory retrieval in AD, and memory encoding and cognitive control impaired in all three groups. 4 key findings →
Evidence: low
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Oxidative stress is deeply involved in multiple pathological processes of VaD. 5 key findings →
Evidence: low
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Vascular dementia (VaD) is a neurodegenerative disorder characterized by chronic oxygen insufficiency, leading to the generation of oxygen-free radicals, inflammatory responses, disturbances in iron metabolism, lipid peroxidation, and other pathological changes that disrupt intracellular homeostasis. 5 key findings →
Evidence: low
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In this review, we outline the significant roles of necroptosis and its molecular mechanisms in the pathological process of VaD, with a particular focus on the role of necroptosis in modulating neuroinflammation and exacerbating the disruption of BBB permeability in VaD, and elaborate on the molecular regulatory mechanisms and the centrally involved cells of necroptosis mediated by tumor necrosis factor-α in neuroinflammation in VaD. 3 key findings →
Evidence: low
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Gait disturbances (odds ratio (OR) = 19.32; p = 0.01), visual-spatial complaints (OR = 6.06; p = 0.03), and visual hallucinations (OR = 31.06; p = 0.002) predicted DLB compared to AD, along with better memory (OR = 3.42; p = 0.003), naming (OR = 3.35; p = 0.002), and worse processing speed (OR = 0.51; p = 0.01). 5 key findings →
Evidence: low
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The spectral analysis of the resting-state eyes-closed electroencephalographic (rsEEG) activity typically shows abnormal delta (< 4 Hz), theta (4-7 Hz), and alpha (8-12 Hz) power in older patients with cognitive deficits due to progressive neurodegenerative diseases. 4 key findings →
Evidence: low
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Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled.
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 30,980 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 30,980 records, built mostly from automated pulls of Europe PMC (65.2% of the library) and OpenAlex (16.4%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,042 records (3.4% of the library) are not peer-reviewed — 967 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →
Newest studies, as a dated timeline → Atom feed Where this research is being discussed: events