28,180 Alzheimer's and dementia studies in plain English, each scored out of 100.
This paper provides a concise but comprehensive review of research on religion/spirituality (R/S) and both mental health and physical health. 1 key finding →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
Despite methodologic limitations, certain risk factors for delirium seem to be consistent and could help identify high-risk patients. 3 key findings →
Participants: 1,365 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Evidence suggests that a high concentration of C-reactive protein (CRP) is a cardiovascular risk factor and an important correlate of cognitive disorders and depression. 4 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source Full text may need a subscription
We found significant independent associations with overall fracture risk in women for age, body mass index, ethnic origin, alcohol intake, smoking status, chronic obstructive pulmonary disease or asthma, any cancer, cardiovascular disease, dementia, diagnosis or treatment for epilepsy, history of falls, chronic liver disease, Parkinson's disease, rheumatoid arthritis or systemic lupus erythematosus, chronic renal disease, type 1 diabetes, type 2 diabetes, previous fracture, endocrine disorders, gastrointestinal malabsorption, any antidepressants, corticosteroids, unopposed hormone replacement therapy, and parental history of osteoporosis. 3 key findings →
Design: cohort study Participants: 3,142,673 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Central immunity components especially microglia in dementia have been well studied and corresponding immunotherapy gradually caught the attention. 4 key findings →
Design: longitudinal study Participants: 361,653 Evidence: moderate
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Grip strength and walking pace have been linked to cognitive dysfunction. 4 key findings →
Design: longitudinal study Participants: 340,212 Evidence: moderate
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Data were drawn from the UK Biobank cohort study with a total of 228 223 participants with Hospital Episodes Statistics and primary care linkage health records. 4 key findings →
Design: cohort study Participants: 2,378 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
A greater sense of meaning and purpose in life is associated with lower dementia risk. 4 key findings →
Design: meta-analysis Participants: 153,445 Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
Epidemiological evidence regarding the association between atrial fibrillation (AF) onset age and risk of incident dementia remains unexplored. 4 key findings →
Design: cohort study Participants: 746 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Dementia occurs in at least 10% of patients within 1 year after stroke. 4 key findings →
Design: cohort study Participants: 218 Evidence: moderate
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Delirium is an acute change in cognition, common in hospitalized older adults, and associated with high healthcare and human cost; however, delirium's genetic and proteomic background remains poorly understood. 4 key findings →
Design: meta-analysis Participants: 1,059,130 Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
= 0.04). Replacing 1 serving per day of nuts and legumes for processed red meat was associated with a 19% lower risk of dementia (HR 0.81, 95% CI 0.75-0.86), 1.37 fewer years of cognitive aging (95% CI -2.49 to -0.25), and a 21% lower risk of SCD (RR 0.79, 95% CI 0.68-0.92). 4 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
From October 2018 to March 2020, 58 participants were recruited (29 per group, 95% [86%-99%]). 5 key findings →
Design: randomized controlled trial Participants: 58 Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
Higher vitamin D intake is associated with decreased risk of dementia in a multiethnic cohort. 4 key findings →
Design: longitudinal study Participants: 329 Evidence: moderate
Full summary, score breakdown and related studies → Original source
In patients aged 65 years and older undergoing hip fracture surgery, regional anesthesia without sedation did not significantly reduce the incidence of postoperative delirium compared with general anesthesia. 3 key findings →
Design: open-label trial Participants: 476 Evidence: high
Full summary, score breakdown and related studies → Original source
Zolpidem use was a strong, independent, and potentially modifiable risk factor for inpatient falls. 5 key findings →
Design: cohort study Participants: 4,962 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Higher visit-to-visit variability in blood pressure independent of average blood pressure was associated with impaired cognitive function in old age. 3 key findings →
Design: cohort study Participants: 5,461 Evidence: moderate
Full summary, score breakdown and related studies → Original source
A higher omega-3 index was correlated with larger total normal brain volume and hippocampal volume in postmenopausal women measured 8 years later. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Most veterans with LLE/AD taking statins for secondary prevention do not discontinue statins following CLC admission. 2 key findings →
Design: cohort study Participants: 13,110 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Diabetes mellitus did not increase the risk of incident AD in the Framingham cohort overall; however, DM may be a risk factor for AD in the absence of other known major AD risk factors. 3 key findings →
Design: cohort study Participants: 2,210 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Liraglutide might slow down memory function decline in diabetic patients in early, and possibly preclinical stages of the disease. 2 key findings →
Participants: 20 Evidence: low
Full summary, score breakdown and related studies → Original source
These results indicate that the use of statins may benefit all AD patients with potentially greater therapeutic efficacy in those homozygous for ApoE4. 5 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
These 20 consensus statements on the use of unilateral cochlear implantation in adults with SNHL were relevant to the following 7 key areas of interest: level of awareness of cochlear implantation (1 consensus statement); best practice clinical pathway from diagnosis to surgery (3 consensus statements); best practice guidelines for surgery (2 consensus statements); clinical effectiveness of cochlear implantation (4 consensus statements); factors associated with postimplantation outcomes (4 consensus statements); association between hearing loss and depression, cognition, and dementia (5 consensus statements); and cost implications of cochlear implantation (1 consensus statement). 2 key findings →
Design: systematic review Evidence: high
Full summary, score breakdown and related studies → Original source
Evidence is emerging that greater exposure to airborne pollutants is associated with increased risk of dementia. 2 key findings →
Design: longitudinal study Evidence: moderate
Full summary, score breakdown and related studies → Original source
PM2.5 exposure may contribute to WM loss in older women. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
10 of the 3,281 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 28,180 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 28,180 records, built mostly from automated pulls of Europe PMC (61.7% of the library) and OpenAlex (18.1%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,034 records (3.7% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →