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small
904 studies tagged small, dated 1975-09-01 to 2026-09-14. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Pathway-specific polygenic risk scores reveal underlying mechanisms of cerebral small vessel disease 2026-09-14
- Cerebral Small Vessel Disease and Risk of Cardiovascular Events and All-Cause Mortality: The Framingham Heart Study 2026-09-07
- Regional Distribution of Mineralized Blood Vessels in Alzheimer Disease and Clinicopathological Associations: A Multicenter Autopsy Study 2026-09-01
Studies
904 studies carry this tag.
Date range
1975 to 2026
Top journals
- Neurology 93
- Stroke 61
- Alzheimer s & Dementia 31
- Brain : a journal of neurology 20
- Annals of neurology 19
342 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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White matter hyperintensities (WMH) on MRI scans indicate lesions of the subcortical fiber system.
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In a previous study of normal elderly male twins, the heritability of quantitative white matter hyperintensity (WMH) volume has been estimated to be high (0.73).
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Though cerebral white matter injury is a frequently described phenomenon in aging and dementia, the cause of white matter lesions has not been conclusively determined.
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40/100
Half of the patients with SSVD complained of varying severity of cognitive problems 3 months after stroke.
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We investigated the nature of the relationship between depression and vascular diseases by reviewing epidemiological, clinical, neuroimaging and neuropathology studies which have reported on the relationship of depression to coronary artery disease, stroke disease, alterations in blood pressure, vascular dementia, diabetes mellitus and cholesterol levels and by reviewing potential mechanisms by which depression could be associated with vascular diseases.
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Log-rank testing, adjusted for matching, showed a highly significant difference in stroke-free survival between the two groups (p<0.0001).
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43/100
Diffusion tensor measurements correlate better with cognition than conventional MRI measures.
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Thorn-shaped astrocytes (TSA) are glial fibrillary tangles that contain abnormally phosphorylated and aggregated microtubule-associated tau protein.
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Diabetic patients are at increased risk for stroke, but little is known about the presence of other brain lesions.
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The cognitive deficits in VaD and VCI are characterized by disturbance of frontal functions, with less verbal memory impairment.
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In stroke- and dementia-free individuals, higher 10-year risk for stroke is associated with performance decrements in multiple cognitive domains.
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Sporadic, late-onset Alzheimer disease (AD) constitutes the most frequent cause of dementia in the elderly population.
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The presence of cognitive impairment in corticobasal degeneration (CBD) is now widely recognised.
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Type 2 diabetes is associated with hippocampal and amygdalar atrophy, regardless of vascular pathology.
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New hippocampal neurons are continuously generated in the adult brain.
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Amyloid deposition can take place in the walls of arteries, arterioles, and, less often, capillaries and veins of the central nervous system, a phenomenon known as cerebral amyloid angiopathy (CAA).
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49/100
Progressive non-fluent aphasia (PNFA) is a syndrome in which patients lose the ability to communicate fluently in the context of relative preservation of single word comprehension and non-linguistic cognitive abilities.
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During 3697 person-years of follow-up (mean per person, 3.6 years), dementia developed in 30 of the 1015 participants.
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36/100
Proof that blood-brain barrier failure is key to these conditions could provide a target for new treatments to reduce the effects of vascular disease on the brain and prevent cognitive decline and dementia.
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Hyperhomocysteinemia is associated with an increased risk of vascular disease, and recent results suggest that it also could increase the risk of dementia.
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Cerebrovascular disease is the second most common cause of acquired cognitive impairment and dementia and contributes to cognitive decline in the neurodegenerative dementias.
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Aceruloplasminemia is an interesting disease, the study of which helps elucidate how iron-induced oxidative stress is involved in neuronal cell death.
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Clinicopathologic data from 285 autopsies were analyzed.
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Infection with the human immunodeficiency virus (HIV) is associated with a syndrome of cognitive and motor abnormalities that may develop in the absence of opportunistic infections.
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Vascular dementia is the second most common type of dementia.
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Latent reservoirs of human immunodeficiency virus (HIV) present significant challenges for eradicating HIV from infected persons, particularly reservoirs in the brain established during acute infection.
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Age has a powerful effect on enhanced susceptibility to neurodegenerative diseases, including susceptibility to stroke and cognitive impairment (CI) even in optimally healthy individuals.
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In recent years, oxidative stress has been implicated in a variety of degenerative processes, diseases, and syndromes.
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Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary cerebrovascular disease leading to cognitive decline and dementia.
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Starting in 1991, participants were assessed with the Cognitive Abilities Screening Instrument (CASI) and diagnosed with dementia (including subtype) based on published criteria.
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25 of the patients needed a shunt operation.
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The early diagnosis of vascular cognitive impairment has been challenged and executive control function has been suggested to be a rational basis for the diagnosis of vascular dementia.
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White matter lesions are frequently found on cerebral MRI scans of elderly people and are thought to be important in the pathogenesis of dementia.
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69/100
Hypertension after age 65 years is not associated with AD and does not adversely affect memory, language, or general cognitive function.
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Silent brain infarcts and white matter lesions are frequently seen on magnetic resonance imaging in healthy elderly people and both are associated with an increased risk of stroke and dementia.
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Cerebral amyloid angiopathy (CAA) is a type of beta-amyloidosis that occurs in leptomeningeal and cortical vessels of the elderly.
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This is the first study that focuses on insomnia in stroke patients.
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The authors illustrate the spectrum of clinical and imaging patterns in primary progressive aphasia (PPA), a syndrome of slowly progressive speech and language impairment occurring with neurodegenerative disease.
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Subcortical lacunes were not related to cognitive measures independent of effects of other MRI variables.
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Shunting INPH is associated with an approximately 29% rate of significant improvement and a 6% significant complication rate.
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The ABILHAND questionnaire results in a valid person-centered measure of manual ability in everyday activities.
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We present a new ARWMC scale applicable to both CT and MRI that has almost equal sensitivity, except for certain regions.
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Vascular disease causes multi-infarct dementia (MID) or Binswanger's disease (BD), the latter of which is a progressive form of vascular dementia (VaD) associated pathologically with fibrinoid and hyaline changes in brain arterioles with injury to the white matter.
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Elevated midlife blood pressures, and the resulting increased white matter hyperintensities, increase the risk for MCI in a group of community-dwelling older men to at least the same degree as apolipoprotein E4 genotype.
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Temporal pole hyperintensity is a radiologic marker of CADASIL.
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Temporoparietal hypoperfusion on SPECT is common to both AD and DLB.
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61/100
This study examined the temporal trends in the incidence rates of HIV dementia, cryptococcal meningitis, toxoplasmosis, progressive multifocal leukoencephalopathy, and CNS lymphoma from January 1990 to December 1998 in the Multicenter AIDS Cohort Study.
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The prevalence and the degree of cerebral white matter lesions increased with age.
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Ischemic vascular dementia (IVD) is a relatively uncommon entity, in the course of which multiple ischemic brain lesions result in progressive cognitive and memory impairment.
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Progressive cerebrovascular atherosclerosis and consecutive stroke are among the most common causes of dementia.
From across this tag
8 of the 903 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 8. The same 8 appear here every time.
- The Science of Vascular Contributions to Cognitive Impairment and Dementia (VCID): A Framework for Advancing Research Priorities in the Cerebrovascular Biology of Cognitive Decline
- Higher Aortic Stiffness Is Related to Lower Cerebral Blood Flow and Preserved Cerebrovascular Reactivity in Older Adults
- Microglia in neurodegenerative disease
- Vasculocentric Axonal NfH in Small Vessel Disease
- Anatomical differences between CBS-corticobasal degeneration and CBS-Alzheimer's disease
- Distinct cerebral perfusion patterns in FTLD and AD
- Cerebromicrovascular senescence in vascular cognitive impairment: does accelerated microvascular aging accompany atherosclerosis?
- MRI biomarkers of vascular damage and atrophy predicting mortality in a memory clinic population