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Newest in this topic

  1. Homocysteine Induces Inflammation in Retina and Brain 2020-03-03
  2. Retinal oximetry: Metabolic imaging for diseases of the retina and brain 2019-04-15
  3. Phosphorylated α-synuclein in the retina is a biomarker of Parkinson's disease pathology severity 2018-05-08

Studies

16 studies carry this tag.

Date range

2009 to 2020

Top journals

  • ACS chemical neuroscience 1
  • Age (Dordrecht, Netherlands) 1
  • Biomolecules 1
  • Current Alzheimer research 1
  • Current opinion in neurology 1

16 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Homocysteine Induces Inflammation in Retina and Brain

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Biomolecules 2020-03-03 Brain scans and imaging

    Homocysteine (Hcy) is an amino acid that requires vitamins B 12 and folic acid for its metabolism.

  2. Retinal oximetry: Metabolic imaging for diseases of the retina and brain

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Progress in retinal and eye research 2019-04-15 Brain scans and imaging

    Retinal oximetry imaging of retinal blood vessels measures oxygen saturation of hemoglobin.

  3. Phosphorylated α-synuclein in the retina is a biomarker of Parkinson's disease pathology severity

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Movement disorders : official journal of the Movement Disorder Society 2018-05-08 Brain scans and imaging

    These data suggest that phosphorylated α-synuclein accumulates in the retina in parallel with that in the brain, including in early stages preceding development of clinical signs of parkinsonism or dementia.

  4. Tau accumulation in the retina promotes early neuronal dysfunction and precedes brain pathology in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Molecular neurodegeneration 2017-08-03 Brain scans and imaging

    Our data demonstrate an age-related increase in endogenous retinal tau characterized by epitope-specific hypo- and hyper-phosphorylation in 3xTg mice.

  5. Glial Cell Calcium Signaling Mediates Capillary Regulation of Blood Flow in the Retina

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2016-09-01 Brain scans and imaging

    The results show that, independent of arterioles, capillaries actively dilate and regulate blood flow.

  6. The estrogenic retina: The potential contribution to healthy aging and age-related neurodegenerative diseases of the retina

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Steroids 2015-08-08 Brain scans and imaging

    These last two decades have seen an explosion of clinical and epidemiological research, and basic research devoted to envisage the influence of gender and hormonal fluctuations in the retina/ocular diseases.

  7. Hyperspectral imaging signatures detect amyloidopathy in Alzheimer's mouse retina well before onset of cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. ACS chemical neuroscience 2014-11-26 Brain scans and imaging

    Amyloidopathic disorders such as Alzheimer's disease present symptomology years after the entrenchment of amyloidogenic imbalance.

  8. Long-term in vivo imaging of fibrillar tau in the retina of P301S transgenic mice

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. PloS one 2012-12-31 Brain scans and imaging

    Tauopathies are widespread neurodegenerative disorders characterised by the intracellular accumulation of hyperphosphorylated tau.

  9. Structural and functional impairment of the retina and optic nerve in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Current Alzheimer research 2012-09-01 Brain scans and imaging

    Our study showed that in patients with AD, even without visual failure there was a decrease in macular and RNFL thickness, as well as a decrease of the electrical activity of the macula.

  10. Alzheimer's disease in the retina: imaging retinal aβ plaques for early diagnosis and therapy assessment

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuro-degenerative diseases 2012-02-10 Brain scans and imaging

    Translation of noninvasive retinal-plaque imaging to humans could eventually facilitate early and accurate AD diagnosis and therapy assessment.

  11. Neuroprotective effects of lutein in the retina

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Current pharmaceutical design 2012-01-01 Brain scans and imaging

    Although a large variety of pharmaceutical therapies for treating disease have been developed in recent years, there has been little progress in disease prevention.

  12. Neurodegeneration of the retina in mouse models of Alzheimer's disease: what can we learn from the retina?

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Age (Dordrecht, Netherlands) 2011-05-11 Brain scans and imaging

    Alzheimer's disease (AD) is an age-related progressive neurodegenerative disease commonly found among elderly.

  13. Cholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degeneration

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of lipid research 2010-06-21 Brain scans and imaging

    This review will discuss the formation and potential implications of 7-ketocholesterol (7KCh) in the retina. 7KCh is a proinflammatory oxysterol known to be present in high amounts in oxidized LDL deposits associated with atheromatous plaques. 7KCh is generated in situ in these lipoprotein deposits where it can accumulate and reach very high concentrations.

  14. Microglia in the healthy and degenerating retina: insights from novel mouse models

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Immunobiology 2010-06-04 Brain scans and imaging

    In contrast to the tremendous amount of research data from the central nervous system, relatively little is known about microglial homeostasis in the retina.

  15. Optical coherence tomography of the retina: applications in neurology

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Current opinion in neurology 2010-02-01 Brain scans and imaging

    This review summarizes the mechanisms and recent developments of optical coherence tomography and its practical uses in neurology.

  16. Amyloid-peptide vaccinations reduce {beta}-amyloid plaques but exacerbate vascular deposition and inflammation in the retina of Alzheimer's transgenic mice

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The American journal of pathology 2009-10-15 Brain scans and imaging

    Alzheimer's disease (AD) is pathologically characterized by accumulation of beta-amyloid (Abeta) protein deposits and/or neurofibrillary tangles in association with progressive cognitive deficits.

All topic tags with their study counts