Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest in this topic

  1. Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease 2022-01-24
  2. Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer's disease 2019-05-24
  3. Down regulation of pro-inflammatory pathways by tanshinone IIA and cryptotanshinone in a non-genetic mouse model of Alzheimer's disease 2017-11-20

Studies

8 studies carry this tag.

Date range

2002 to 2022

Top journals

  • Cell death and differentiation 1
  • Frontiers in neuroscience 1
  • International journal of pharmaceutics 1
  • Journal of neurochemistry 1
  • Neurobiology of aging 1

8 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Frontiers in neuroscience 2022-01-24 Biomarkers

    Animal models of disease are valuable resources for investigating pathogenic mechanisms and potential therapeutic interventions.

  2. Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Cell death and differentiation 2019-05-24 Biomarkers

    Amyloid-β (Aβ) oligomers largely initiate the cascade underlying the pathology of Alzheimer's disease (AD).

  3. Down regulation of pro-inflammatory pathways by tanshinone IIA and cryptotanshinone in a non-genetic mouse model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Pharmacological research 2017-11-20 Biomarkers

    Alzheimer's disease (AD) is a common form of dementia mainly characterized by the deposition of neurofibrillary tangles and β-amyloid (Aβ) peptides in the brain.

  4. Effect of the oral administration of nanoencapsulated quercetin on a mouse model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. International journal of pharmaceutics 2016-11-30 Biomarkers

    Quercetin has been identified as a promising compound with a neuroprotective potential against age-related neurodegenerative diseases such as Alzheimer's disease (AD).

  5. Fingolimod modulates multiple neuroinflammatory markers in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Scientific reports 2016-04-27 Biomarkers

    Sphingosine 1-phosphate (SP1) receptors may be attractive targets for modulation of inflammatory processes in neurodegenerative diseases.

  6. Bioluminescence imaging of Abeta deposition in bigenic mouse models of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2011-01-24 Biomarkers

    Transgenic (Tg) mouse models of Alzheimer's disease have served as valuable tools for investigating pathogenic mechanisms related to Aβ accumulation.

  7. Inflammatory changes are tightly associated with neurodegeneration in the brain and spinal cord of the APP/PS1KI mouse model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of aging 2008-07-26 Biomarkers

    Inflammatory processes are considered to play an important role in the progression of neurodegenerative changes in Alzheimer's disease (AD).

  8. Chronic nicotine treatment reduces beta-amyloidosis in the brain of a mouse model of Alzheimer's disease (APPsw)

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of neurochemistry 2002-05-01 Biomarkers

    Alzheimer's disease neuropathology is characterised by beta-amyloid plaques and neurofibrillary tangles.

All topic tags with their study counts