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plasma-amyloid
16 studies tagged plasma-amyloid, dated 2011-03-03 to 2023-05-26. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Reference intervals for plasma amyloid-β, total tau, and phosphorylated tau181 in healthy elderly Chinese individuals without cognitive impairment 2023-05-26
- Plasma Amyloid-β, Total Tau, and Neurofilament Light Chain Across the Alzheimer's Disease Clinical Spectrum: A Population-Based Study 2023-01-01
- Plasma β-amyloid, tau, neurodegeneration biomarkers and inflammatory factors of probable Alzheimer's disease dementia in Chinese individuals 2022-08-18
Studies
16 studies carry this tag.
Date range
2011 to 2023
Top journals
- Journal of Alzheimer's disease : JAD 5
- Frontiers in aging neuroscience 3
- Alzheimer's & dementia (Amsterdam, Netherlands) 1
- Alzheimer's research & therapy 1
- Experimental gerontology 1
10 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Reference intervals for plasma biomarkers of AD may assist clinicians in making accurate clinical decisions.
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In this Chinese population, AD plasma biomarkers vary by age, sex, and APOE genotype.
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The levels of plasma ATN biomarkers (Aβ42/Aβ40 ratio, p-tua181, and NfL) were significantly changed in clinically diagnosed AD patients and they all associated with different domains of cognitive impairment.
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Depressed individuals are twice as likely to develop Alzheimer's disease (AD) as compared to controls.
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Plasma Aβ40, Aβ42, and P-Tau proteins in the NC, aMCI, and AD groups increased with the progression of AD ( P < 0.01); cortical thickness reductions in the AD-aMCI groups and AD-NC groups mainly involved the bilateral superior temporal gyrus, transverse temporal gyrus, superior marginal gyrus, insula, right entorhinal cortex, right fusiform gyrus, and cingulate gyrus.
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BCG vaccine has been used for 100 years to prevent tuberculosis.
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After adjusting for age, sex, and the apolipoprotein E ( APOE ) alleles, compared to the CN group, the plasma t-tau, and NfL were significantly increased in the AD group ( p < 0.01, Bonferroni correction).
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The poor correlations for Aβ42 in plasma might have several potential explanations, such as the high levels of plasma proteins (compared to CSF), sensitivity to pre-analytical sample handling and specificity, and cross-reactivity of different antibodies.
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Midlife measurement of plasma Aβ may have utility as a blood-based biomarker indicative of risk for future cognitive impairment.
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In this sample, the high-throughput blood Aβ assay was not able to distinguish well between AD patients and controls.
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Detection of amyloid-β (Aβ) aggregates contributes to the diagnosis of Alzheimer disease (AD).
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Levels of plasma Aβ42 and Aβ42/Aβ40 ratio were elevated in patients with possible cognitive impairment, indicating that plasma Aβ42 and Aβ42/Aβ40 ratio increases may be more pronounced in early stage of cognitive impairment.
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We discovered age-dependent genetic effects, established associations between vascular-related genes (KLKB1, F12, PLIN2) and midlife plasma aβ levels, and identified a plausible Alzheimer's Disease candidate gene (ITPRIP) influencing cell death.
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Type 2 diabetes is associated with altered plasma concentrations of Aβ peptides and is an important source of variation that needs to be taken into account when considering plasma Aβ peptides as biomarkers for Alzheimer's disease.
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Serum NGAL levels are increased in DS and associated with distinct species of Aβ depending on the progression of dementia as diagnosed by baseline and follow-up clinical assessments.
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Aging dogs naturally demonstrate cognitive impairment and neuropathology that model early Alzheimer's disease (AD).