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Newest in this topic

  1. Age- and disease-specific reference values for neurofilament light presented in an online interactive support interface 2022-10-05
  2. Plasma neurofilament light chain as a biomarker of Alzheimer's disease in Subjective Cognitive Decline and Mild Cognitive Impairment 2022-03-14
  3. Plasma p-tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total tau 2021-12-02

Studies

8 studies carry this tag.

Date range

2007 to 2022

Top journals

  • Alzheimer's & dementia (Amsterdam, Netherlands) 1
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 1
  • Alzheimer's research & therapy 1
  • Annals of clinical and translational neurology 1
  • BMC neurology 1

8 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Age- and disease-specific reference values for neurofilament light presented in an online interactive support interface

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Annals of clinical and translational neurology 2022-10-05 Biomarkers

    Interpretation of axonal damage biomarker Neurofilament Light chain (NfL) concentrations is difficult due to the lack of age-specific and disease-specific reference values.

  2. Plasma neurofilament light chain as a biomarker of Alzheimer's disease in Subjective Cognitive Decline and Mild Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Journal of neurology 2022-03-14 Biomarkers

    Plasma NfL levels might be a promising biomarker for neurodegeneration to discriminate cognitive decline due to AD from other conditions causing cognitive impairment in prodromal stages.

  3. Plasma p-tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total tau

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2021-12-02 Biomarkers

    These results support plasma p-tau 181 for the detection of AD dementia and the use of blood-based biomarkers for optimal disease detection.

  4. The diagnostic performance of neurofilament light chain in CSF and blood for Alzheimer's disease, frontotemporal dementia, and amyotrophic lateral sclerosis: A systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2019-11-04 Biomarkers

    Comparable performance of CSF and blood NfL in many groups demonstrates the promise of NfL as a noninvasive biomarker of neurodegeneration; however, its utility in clinically meaningful scenarios requires greater scrutiny.

  5. Neurofilament light chain protein in neurodegenerative dementia: A systematic review and network meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Neuroscience and biobehavioral reviews 2019-04-24 Biomarkers

    The diagnostic value of neurofilament light chain protein in neurodegenerative dementia diseases is still controversial.

  6. The CSF neurofilament light signature in rapidly progressive neurodegenerative dementias

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Alzheimer's research & therapy 2018-01-11 Biomarkers

    The present data indicate that CSF NfL and t-tau levels reflect distinct pathophysiological mechanisms of neurodegeneration and support the clinical use of NfL as a fast screening biomarker for the differential diagnosis of atypical/rapidly progressive NDs.

  7. Cerebrospinal fluid neurofilament light chain protein levels in subtypes of frontotemporal dementia

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. BMC neurology 2013-05-29 Biomarkers

    The marked NFL elevation in some but not all FTD cases is likely to reflect the different underlying pathologies.

  8. Elevated cerebrospinal fluid neurofilament light protein concentrations predict the development of AIDS dementia complex

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. The Journal of infectious diseases 2007-05-02 Biomarkers

    The light subunit of neurofilament protein (NFL) is a sensitive indicator of central nervous system axonal injury.

All topic tags with their study counts