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Home › Research › Topics › light-chain

light-chain

9 studies tagged light-chain, dated 2013-05-29 to 2024-04-20. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Serum neurofilament light chain and inflammatory cytokines as biomarkers for early detection of mild cognitive impairment 2024-04-20
  2. Potential Utility of Plasma P-Tau and Neurofilament Light Chain as Surrogate Biomarkers for Preventive Clinical Trials 2023-03-06
  3. Plasma neurofilament light chain as a biomarker of Alzheimer's disease in Subjective Cognitive Decline and Mild Cognitive Impairment 2022-03-14

Studies

9 studies carry this tag.

Date range

2013 to 2024

Top journals

  • Journal of neurology 2
  • Alzheimer's & dementia (Amsterdam, Netherlands) 1
  • Annals of neurology 1
  • BMC neurology 1
  • European journal of neurology 1

8 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Serum neurofilament light chain and inflammatory cytokines as biomarkers for early detection of mild cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Scientific reports 2024-04-20 Biomarkers

    To investigate the association between serum neurofilament light chain (NfL) levels, inflammatory cytokines, and cognitive function to assess their utility in the early detection of mild cognitive impairment (MCI).

  2. Potential Utility of Plasma P-Tau and Neurofilament Light Chain as Surrogate Biomarkers for Preventive Clinical Trials

    ✓ Peer-reviewed alzhub usefulness score 74 out of 100. Neurology 2023-03-06 Biomarkers

    Plasma p-tau181/NfL can potentially be used to monitor large-scale population interventions in CU individuals.

  3. Plasma neurofilament light chain as a biomarker of Alzheimer's disease in Subjective Cognitive Decline and Mild Cognitive Impairment

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Journal of neurology 2022-03-14 Biomarkers

    Plasma NfL levels might be a promising biomarker for neurodegeneration to discriminate cognitive decline due to AD from other conditions causing cognitive impairment in prodromal stages.

  4. Serum neurofilament light chain as a surrogate of cognitive decline in sporadic and familial frontotemporal dementia

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. European journal of neurology 2021-09-03 Biomarkers

    Our findings highlight the potential of serum NfL as a useful surrogate end point of disease severity in upcoming targeted treatments.

  5. Alpha-Synuclein Oligomers and Neurofilament Light Chain Predict Phenoconversion of Pure Autonomic Failure

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Annals of neurology 2021-04-30 Biomarkers

    αSyn-PMCA is almost invariably positive in the CSF of patients with PAF establishing this condition as α-synucleinopathy.

  6. The diagnostic performance of neurofilament light chain in CSF and blood for Alzheimer's disease, frontotemporal dementia, and amyotrophic lateral sclerosis: A systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2019-11-04 Biomarkers

    Comparable performance of CSF and blood NfL in many groups demonstrates the promise of NfL as a noninvasive biomarker of neurodegeneration; however, its utility in clinically meaningful scenarios requires greater scrutiny.

  7. Serum neurofilament light chain is a discriminative biomarker between frontotemporal lobar degeneration and primary psychiatric disorders

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Journal of neurology 2019-10-08 Biomarkers

    Due to the significant clinical overlap between frontotemporal lobar degeneration (FTLD) spectrum disorders and late-onset primary psychiatric disorders (PPD), diagnostic biomarkers reflecting the different underlying pathophysiologies are urgently needed.

  8. Neurofilament light chain protein in neurodegenerative dementia: A systematic review and network meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Neuroscience and biobehavioral reviews 2019-04-24 Biomarkers

    The diagnostic value of neurofilament light chain protein in neurodegenerative dementia diseases is still controversial.

  9. Cerebrospinal fluid neurofilament light chain protein levels in subtypes of frontotemporal dementia

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. BMC neurology 2013-05-29 Biomarkers

    The marked NFL elevation in some but not all FTD cases is likely to reflect the different underlying pathologies.

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