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Home › Research › Topics › pet

pet

1,163 studies tagged pet, dated 1983-08-01 to 2026-11-01. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Large-scale head-to-head comparison of on- and off-target profiles of [18F]Tauvid and [18F]MK6240 tau-PET in aging and Alzheimer’s disease 2026-11-01
  2. Detection of tau spatial extent using MK6240 and flortaucipir PET 2026-10-28
  3. Soluble amyloid composition links proximal APP processing, fibrillar burden and the p-tau181 response 2026-10-22

Studies

1,163 studies carry this tag.

Date range

1983 to 2026

Top journals

  • Neurology 88
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 58
  • Brain : a journal of neurology 52
  • Journal of nuclear medicine : official publication, Society of Nuclear Medicine 52
  • Alzheimer's research & therapy 34

337 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Impact of molecular imaging on the diagnostic process in a memory clinic

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2012-11-16 Mild cognitive impairment

    [(11)C]PIB scans were positive in 40 of 66 (61%) patients with a clinical diagnosis of Alzheimer's disease (AD), 5 of 18 (28%) patients with frontotemporal dementia (FTD), 4 of 5 (80%) patients with Lewy body dementia, and 3 of 10 (30%) patients with other dementias. [(18)F]FDG uptake patterns matched the clinical diagnosis in 38 of 66 (58%) of AD patients, and in 6 of 18 (33%) FTD patients.

  2. Meta-analysis based SVM classification enables accurate detection of Alzheimer's disease across different clinical centers using FDG-PET and MRI

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Psychiatry research 2012-11-10 Long-term cohort studies

    The application of support vector machine classification (SVM) to combined information from magnetic resonance imaging (MRI) and [F18]fluorodeoxyglucose positron emission tomography (FDG-PET) has been shown to improve detection and differentiation of Alzheimer's disease dementia (AD) and frontotemporal lobar degeneration.

  3. A direct morphometric comparison of five labeling protocols for multi-atlas driven automatic segmentation of the hippocampus in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. NeuroImage 2012-11-07 Long-term cohort studies

    Hippocampal volumetry derived from structural MRI is increasingly used to delineate regions of interest for functional measurements, assess efficacy in therapeutic trials of Alzheimer's disease (AD) and has been endorsed by the new AD diagnostic guidelines as a radiological marker of disease progression.

  4. Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. The Lancet. Neurology 2012-11-06 Prevention and risk

    44 participants were included: 20 PSEN1 E280A mutation carriers and 24 non-carriers.

  5. Florbetapir PET analysis of amyloid-β deposition in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional study

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. The Lancet. Neurology 2012-11-06 Prevention and risk

    These findings contribute to the understanding of preclinical familial Alzheimer's disease and help set the stage for assessment of amyloid-modifying treatments in the prevention of familial Alzheimer's disease.

  6. Amyloid deposition, hypometabolism, and longitudinal cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Annals of neurology 2012-10-01 Brain tissue and pathology

    Using data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) population, we examined (1) cross-sectional relationships between amyloid deposition, hypometabolism, and cognition, and (2) associations between amyloid and hypometabolism measurements and longitudinal cognitive measurements.

  7. Injury markers predict time to dementia in subjects with MCI and amyloid pathology

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Neurology 2012-09-26 Genetics

    In subjects with MCI and evidence of amyloid pathology, the injury markers CSF t-tau and p-tau and hippocampal atrophy can predict further cognitive decline.

  8. Toward a predictive model of Alzheimer's disease progression using capillary electrophoresis-mass spectrometry metabolomics

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Analytical chemistry 2012-09-25 Mild cognitive impairment

    Alzheimer's disease (AD) is the most prevalent form of dementia with an estimated worldwide prevalence of over 30 million people, and its incidence is expected to increase dramatically with an increasing elderly population.

  9. A European multicentre PET study of fibrillar amyloid in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. European journal of nuclear medicine and molecular imaging 2012-09-08 Mild cognitive impairment

    [(11)C]PIB retention in the neocortical and subcortical brain regions was significantly higher in AD patients than in age-matched controls.

  10. Neuroimaging correlates of pathologically defined subtypes of Alzheimer's disease: a case-control study

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. The Lancet. Neurology 2012-09-03 Caregiving

    Compared with typical AD, hippocampal-sparing AD has more neurofibrillary tangles in the cortex and fewer in the hippocampus, whereas the opposite pattern is seen in limbic-predominant AD.

  11. Increased cerebral metabolism after 1 year of deep brain stimulation in Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Archives of neurology 2012-09-01 Brain scans and imaging

    Increased connectivity after 1 year of DBS is observed, which is in contrast to the decreased connectivity observed over the course of AD.

  12. Subjective cognitive complaints and amyloid burden in cognitively normal older individuals

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuropsychologia 2012-08-23 Brain scans and imaging

    Accumulating evidence suggests that subjective cognitive complaints (SCC) may indicate subtle cognitive decline characteristic of individuals with preclinical Alzheimer's disease (AD).

  13. Amyloid-β assessed by florbetapir F 18 PET and 18-month cognitive decline: a multicenter study

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Neurology 2012-07-11 Cognitive tests and assessment

    Florbetapir F 18 PET can image amyloid-β (Aβ) aggregates in the brains of living subjects.

  14. Amyloid imaging in Alzheimer's disease: comparison of florbetapir and Pittsburgh compound-B positron emission tomography

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of neurology, neurosurgery, and psychiatry 2012-07-11 Brain scans and imaging

    Both ligands displayed highly significant group discrimination and correlation of regional uptake.

  15. Brain excitability and connectivity of neuronal assemblies in Alzheimer's disease: from animal models to human findings

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Progress in neurobiology 2012-07-10 Brain scans and imaging

    The human brain contains about 100 billion neurons forming an intricate network of innumerable connections, which continuously adapt and rewire themselves following inputs from external and internal environments as well as the physiological synaptic, dendritic and axonal sculpture during brain maturation and throughout the life span.

  16. Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. The Lancet. Neurology 2012-06-28 Getting a diagnosis

    For one of the primary analyses, the interpretation of the florbetapir scans (majority interpretation of five nuclear medicine physicians, who classified each scan as amyloid positive or amyloid negative) was compared with amyloid pathology (assessed according to the Consortium to Establish a Registry for Alzheimer's Disease standards, and classed as amyloid positive for moderate or frequent plaques or amyloid negative for no or sparse plaques); correlation of the image analysis results with amyloid burden was tested as a coprimary endpoint.

  17. Disruption of functional brain networks in Alzheimer's disease: what can we learn from graph spectral analysis of resting-state magnetoencephalography?

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Brain connectivity 2012-06-11 Brain scans and imaging

    In Alzheimer's disease (AD), structural and functional brain network organization is disturbed.

  18. Regional dynamics of amyloid-β deposition in healthy elderly, mild cognitive impairment and Alzheimer's disease: a voxelwise PiB-PET longitudinal study

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Brain : a journal of neurology 2012-05-23 Mild cognitive impairment

    However, few longitudinal Pittsburgh compound B-positron emission tomography studies have tested this hypothesis, and with conflicting results.

  19. Wavelet coherence model for diagnosis of Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 42 out of 100. Clinical EEG and neuroscience 2012-05-10 Brain scans and imaging

    This article presents a wavelet coherence investigation of electroencephalograph (EEG) readings acquired from patients with Alzheimer disease (AD) and healthy controls.

  20. Longitudinal imaging of Alzheimer pathology using [11C]PIB, [18F]FDDNP and [18F]FDG PET

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. European journal of nuclear medicine and molecular imaging 2012-03-23 Mild cognitive impairment

    A significant increase in global cortical [(11)C]PIB BP(ND) was found in MCI patients, but no changes were observed in AD patients or controls.

  21. Small-animal PET imaging of amyloid-beta plaques with [11C]PiB and its multi-modal validation in an APP/PS1 mouse model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. PloS one 2012-03-09 Brain scans and imaging

    In vivo imaging and quantification of amyloid-β plaque (Aβ) burden in small-animal models of Alzheimer's disease (AD) is a valuable tool for translational research such as developing specific imaging markers and monitoring new therapy approaches.

  22. Diagnostic accuracy of the MMSE in detecting probable and possible Alzheimer's disease in ethnically diverse highly educated individuals: an analysis of the NACC database

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. The journals of gerontology. Series A, Biological sciences and medical sciences 2012-03-06 Long-term cohort studies

    Arch Neurol. 2008;65(7):963-967.) for the Mini-Mental State Examination in detecting cognitive dysfunction in a bilingual sample of highly educated ethnically diverse individuals.

  23. Voxelwise meta-analysis of gray matter anomalies in Alzheimer's disease and mild cognitive impairment using anatomic likelihood estimation

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Journal of the neurological sciences 2012-03-03 Mild cognitive impairment

    Our meta-analysis identified similar distributions of neuroanatomical changes in AD and MCI, which are consistent with the hierarchical model of neuropathological alterations of neurofibrillary tangles in AD and MCI.

  24. Performance Characteristics of Amyloid PET with Florbetapir F 18 in Patients with Alzheimer's Disease and Cognitively Normal Subjects

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Journal of Nuclear Medicine 2012-02-13 Brain scans and imaging

    Florbetapir F 18 appears to have a wide effective dose range and a high test-retest reliability for both quantitative (SUVr) values and visual assessment of the ligand.

  25. Clinical validation of 18F-AZD4694, an amyloid-β-specific PET radioligand

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012-02-09 Brain scans and imaging

    Noninvasive quantitative approaches provide valid estimates of amyloid-β binding.

  26. Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. The Lancet. Neurology 2012-02-03 Genetics

    We used Kaplan-Meier survival analysis to examine the distribution of incident ARIA-E from the start of bapineuzumab treatment and proportional hazards regression models to assess risk factors associated with ARIA.

  27. Automatic voxel-based morphometry of structural MRI by SPM8 plus diffeomorphic anatomic registration through exponentiated lie algebra improves the diagnosis of probable Alzheimer Disease

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. AJNR. American journal of neuroradiology 2012-02-02 Brain scans and imaging

    This software program with application of SPM8 plus DARTEL to VBM provides a high performance for AD diagnosis by using MRI.

  28. Subjective cognition and amyloid deposition imaging: a Pittsburgh Compound B positron emission tomography study in normal elderly individuals

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Archives of neurology 2012-02-01 Brain scans and imaging

    A decrease of self-confidence about memory abilities in cognitively normal elderly subjects may be related to the neuropathological hallmark of AD measured with PiB-positron emission tomography.

  29. Using PET with 18F-AV-45 (florbetapir) to quantify brain amyloid load in a clinical environment

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. European Journal of Nuclear Medicine and Molecular Imaging 2012-01-17 Brain scans and imaging

    The mean values of SUVr were higher in AD patients (median 1.20, Q1-Q3 1.16-1.30) than in HC subjects (median 1.05, Q1-Q3 1.04-1.08; p = 0.0001) in the overall cortex and all cortical regions (precuneus, anterior and posterior cingulate, and frontal median, temporal, parietal and occipital cortex).

  30. White matter integrity and reaction time intraindividual variability in healthy aging and early-stage Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 42 out of 100. Neuropsychologia 2011-12-08 Brain scans and imaging

    Aging and early-stage Alzheimer disease (AD) have been shown to be associated with increased RT intraindividual variability (IIV, as reflected by the coefficient of variation) and an exaggeration of the slow tail of the reaction time (RT) distribution in attentional control tasks, based on ex-Gaussian analyses.

  31. Amyloid imaging as a biomarker for cerebral β-amyloidosis and risk prediction for Alzheimer dementia

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Neurobiology of aging 2011-12-01 Brain scans and imaging

    Since the introduction of amyloid imaging nearly 10 years ago, this technique has gained widespread use and acceptance.

  32. Amyloid vs FDG-PET in the differential diagnosis of AD and FTLD

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Neurology 2011-11-30 Brain scans and imaging

    PiB and FDG showed similar accuracy in discriminating AD and FTLD.

  33. Voxel-level comparison of arterial spin-labeled perfusion MRI and FDG-PET in Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Neurology 2011-11-16 Brain scans and imaging

    Our voxel-wise results indicated that ASL-MRI provides largely overlapping information with FDG-PET.

  34. PET amyloid-beta imaging in preclinical Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Biochimica et biophysica acta 2011-11-12 Prevention and risk

    Alzheimer's disease (AD) is the leading cause of dementia, accounting for 60-70% of all cases [Hebert et al., 2003, 1].

  35. High dimensional classification of structural MRI Alzheimer's disease data based on large scale regularization

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Frontiers in neuroinformatics 2011-10-14 Brain scans and imaging

    In this work we use a large scale regularization approach based on penalized logistic regression to automatically classify structural MRI images (sMRI) according to cognitive status.

  36. Multi-method analysis of MRI images in early diagnostics of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. PloS one 2011-10-13 Hippocampus size on brain scans

    The role of structural brain magnetic resonance imaging (MRI) is becoming more and more emphasized in the early diagnostics of Alzheimer's disease (AD).

  37. Brain amyloid imaging

    ✓ Peer-reviewed alzhub usefulness score 42 out of 100. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011-09-14 Brain scans and imaging

    Imaging of brain β-amyloid plaques with (18)F-labeled tracers for PET will likely be available in clinical practice to assist the diagnosis of Alzheimer disease (AD).

  38. Subtypes of progressive aphasia: application of the International Consensus Criteria and validation using β-amyloid imaging

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Brain : a journal of neurology 2011-09-09 Brain scans and imaging

    The semantic and non-fluent/agrammatic variants are largely associated with frontotemporal lobar degeneration with TDP-43 and tau pathology, respectively.

  39. Amyloid imaging with (18)F-florbetaben in Alzheimer disease and other dementias

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011-07-15 Getting a diagnosis

    When compared with the other groups, AD patients demonstrated significantly higher SUVRs (P Conclusion (18)F-florbetaben had high sensitivity for AD, clearly distinguished patients with FTLD from AD, and provided results comparable to those reported with (11)C-Pittsburgh Compound B in a variety of neurodegenerative diseases.

  40. Evaluation of a calibrated (18)F-FDG PET score as a biomarker for progression in Alzheimer disease and mild cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011-07-15 Long-term cohort studies

    Increasingly, clinical trials are being planned in patients with mild cognitive impairment (MCI) to prevent or delay the onset of dementia in Alzheimer disease (AD) by disease-modifying intervention.

  41. Association between in vivo fluorine 18-labeled flutemetamol amyloid positron emission tomography imaging and in vivo cerebral cortical histopathology

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Archives of neurology 2011-07-11 Biomarkers

    There was complete agreement between visual reads of ¹⁸F-flutemetamol PET scans (3 blinded readers with majority rule) and histology.

  42. Using positron emission tomography and florbetapir F18 to image cortical amyloid in patients with mild cognitive impairment or dementia due to Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Archives of neurology 2011-07-11 Genetics

    It introduces criteria to determine whether an image is associated with an intermediate-to-high likelihood of pathologic AD or with having any identifiable cortical amyloid level above that seen in low-risk young controls.

  43. AddNeuroMed and ADNI: similar patterns of Alzheimer's atrophy and automated MRI classification accuracy in Europe and North America

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. NeuroImage 2011-07-01 Brain scans and imaging

    The European Union AddNeuroMed program and the US-based Alzheimer Disease Neuroimaging Initiative (ADNI) are two large multi-center initiatives designed to collect and validate biomarker data for Alzheimer's disease (AD).

  44. Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer’s Association Research Roundtable Workgroup

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Alzheimer s & Dementia 2011-07-01 Clinical safety

    The Alzheimer's Association Research Roundtable convened a working group to review data on amyloid imaging related abnormalities (ARIA) in response to concerns raised by the Food and Drug Administration.

  45. Clinical amyloid imaging in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. The Lancet. Neurology 2011-07-01 Treatments

    The hypothesis that amyloid deposition is the leading cause of Alzheimer's disease (AD) is supported by findings in transgenic animal models and forms the basis of clinical trials of anti-amyloid agents.

  46. Neuroimaging markers for the prediction and early diagnosis of Alzheimer's disease dementia

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Trends in neurosciences 2011-06-21 Mild cognitive impairment

    Alzheimer's disease (AD) is a progressive age-related neurodegenerative disease.

  47. Test-retest reliability of memory task functional magnetic resonance imaging in Alzheimer disease clinical trials

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Archives of neurology 2011-05-01 Treatments

    Encoding-task fMRI was successfully implemented in a single-site, 24-week, AD randomized controlled trial.

  48. Resting bold fMRI differentiates dementia with Lewy bodies vs Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Neurology 2011-04-27 Brain scans and imaging

    Changes in functional connectivity in DLB indicate patterns of activation that are distinct from those seen in AD and may improve discrimination of DLB from AD and cognitively normal individuals.

  49. Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Neurology 2011-04-13 Getting a diagnosis

    AD-signature cortical thinning in CN-AD converters in both samples was remarkably similar, about 0.2 mm (p 1).

  50. Cerebral amyloid-β PET with florbetaben (18F) in patients with Alzheimer's disease and healthy controls: a multicentre phase 2 diagnostic study

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. The Lancet. Neurology 2011-04-08 Getting a diagnosis

    81 participants with probable Alzheimer's disease and 69 healthy controls were assessed.

From across this tag

10 of the 1,159 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

All topic tags with their study counts