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Newest in this topic

  1. Assessment of Plasma and Cerebrospinal Fluid Biomarkers in Different Stages of Alzheimer's Disease and Frontotemporal Dementia 2023-01-08
  2. Serum neurofilament light chain as a surrogate of cognitive decline in sporadic and familial frontotemporal dementia 2021-09-03
  3. Synergistic Association between Plasma Aβ1-42 and p-tau in Alzheimer's Disease but Not in Parkinson's Disease or Frontotemporal Dementia 2021-04-07

Studies

10 studies carry this tag.

Date range

2013 to 2023

Top journals

  • Journal of neurology, neurosurgery, and psychiatry 3
  • ACS chemical neuroscience 1
  • Alzheimer's & dementia (Amsterdam, Netherlands) 1
  • BMC neurology 1
  • Dementia and geriatric cognitive disorders 1

8 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Assessment of Plasma and Cerebrospinal Fluid Biomarkers in Different Stages of Alzheimer's Disease and Frontotemporal Dementia

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. International journal of molecular sciences 2023-01-08 Biomarkers

    Alzheimer's disease (AD) is the primary type of dementia, followed by frontotemporal lobar degeneration (FTLD).

  2. Serum neurofilament light chain as a surrogate of cognitive decline in sporadic and familial frontotemporal dementia

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. European journal of neurology 2021-09-03 Biomarkers

    Our findings highlight the potential of serum NfL as a useful surrogate end point of disease severity in upcoming targeted treatments.

  3. Synergistic Association between Plasma Aβ1-42 and p-tau in Alzheimer's Disease but Not in Parkinson's Disease or Frontotemporal Dementia

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. ACS chemical neuroscience 2021-04-07 Biomarkers

    Beta-amyloid (Aβ 1-42 ) triggers the phosphorylation of tau protein in Alzheimer's disease (AD), but the relationship between phosphorylated tau (p-tau) and Aβ 1-42 in the blood is not elucidated.

  4. Fluid biomarkers in frontotemporal dementia: past, present and future

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Journal of neurology, neurosurgery, and psychiatry 2020-11-13 Biomarkers

    The frontotemporal dementia (FTD) spectrum of neurodegenerative disorders includes a heterogeneous group of conditions.

  5. Cerebrospinal Fluid YKL-40 and Chitotriosidase Levels in Frontotemporal Dementia Vary by Clinical, Genetic and Pathological Subtype

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Dementia and geriatric cognitive disorders 2020-04-28 Biomarkers

    CSF YKL-40 and chitotriosidase levels are increased in individuals with clinical FTD syndromes, particularly due to AD pathology.

  6. Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Journal of neurology, neurosurgery, and psychiatry 2020-04-09 Biomarkers

    We conclude that NPTX2 is a promising synapse-derived disease progression biomarker in genetic FTD.

  7. The diagnostic performance of neurofilament light chain in CSF and blood for Alzheimer's disease, frontotemporal dementia, and amyotrophic lateral sclerosis: A systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2019-11-04 Biomarkers

    Comparable performance of CSF and blood NfL in many groups demonstrates the promise of NfL as a noninvasive biomarker of neurodegeneration; however, its utility in clinically meaningful scenarios requires greater scrutiny.

  8. Different neuroinflammatory profile in amyotrophic lateral sclerosis and frontotemporal dementia is linked to the clinical phase

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Journal of neurology, neurosurgery, and psychiatry 2018-09-17 Biomarkers

    Our data indicate that neuroinflammation is linked to the symptomatic phase of ALS/FTD and shows a similar pattern in sporadic and genetic cases.

  9. Clinical value of neurofilament and phospho-tau/tau ratio in the frontotemporal dementia spectrum

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Neurology 2018-03-07 Biomarkers

    NfL and p/t-tau similarly discriminated FTD from controls, but not between clinical subtypes, apart from FTD-MND.

  10. Cerebrospinal fluid neurofilament light chain protein levels in subtypes of frontotemporal dementia

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. BMC neurology 2013-05-29 Biomarkers

    The marked NFL elevation in some but not all FTD cases is likely to reflect the different underlying pathologies.

All topic tags with their study counts