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microbiota
173 studies tagged microbiota, dated 1998-01-01 to 2026-10-23. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Evidence that the perinatal maternal microbiome mediates metabolite signaling programs that drive sex-specific microglial metabolic alterations and Alzheimer’s disease susceptibility 2026-10-23
- Change in gut microbiome precedes symptomatic Alzheimer’s disease and is correlated with amyloid-beta accumulation in the brain 2026-10-19
- The microbial soy metabolite S-equol mitigates cadmium neurotoxicity in mice 2026-10-06
Studies
173 studies carry this tag.
Date range
1998 to 2026
Top journals
- Journal of Alzheimer's disease : JAD 13
- Scientific reports 8
- Molecular neurobiology 5
- bioRxiv 5
- Aging 4
104 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Common themes in the current literature include GMB components; interactions on cognitive development; effects of GMB-gut-brain interactions on cognition, mild cognitive impairment and Alzheimer's disease; effects of GMB interactions with physiologic stress on cognition in critical care; and GMB modification for improved cognition.
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Alzheimer's disease (AD), the most common cause of dementia, is a neurodegenerative disease that seriously threatens human health and life quality.
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Alzheimer's disease (AD), the most common form of dementia, is a leading cause of death and a major cause of morbidity in older people.
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Alzheimer's disease (AD) and Parkinson's disease (PD) are neurodegenerative diseases (NDD) characterized by progressive degeneration of the central nervous system, and few medications are available to halt the progression of AD and PD.
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Akk effectively improved glucose tolerance, intestine barrier dysfunction and dyslipidemia in AD model mice.
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Alzheimer's disease is characterized by the accumulation of amyloid and dysfunctional tau protein in the brain along with the final development of dementia.
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Gut microbiome is a community of microorganisms in the gastrointestinal tract.
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Alzheimer's disease (AD) is a central degenerative disease characterized by cognitive impairment.
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Our pre-experiments found that the brain circRNA sequence profiles and gut microbiota in AD-like mice were changed, as circNF1-419 could enhance autophagy to ameliorate senile dementia in AD-like mice, so we conclude that there might some connections between circRNA and gut microbiome.
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Microbial agents including periodontal pathogens have recently appeared as important actors in Alzheimer's disease (AD) pathology.
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43/100
In both cohorts, few differences between the control and AD groups were observed in terms of alpha and beta diversities, phyla and genera proportions.
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We report a novel association between gut microbiota-related products and systemic inflammation with brain amyloidosis via endothelial dysfunction, suggesting that SCFAs and LPS represent candidate pathophysiologic links between the gut microbiota and AD pathology.
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Scope Recent evidences demonstrate that abnormal gut microbiota (GM) might be involved in the pathogenesis of Alzheimer's disease (AD).
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Alzheimer's disease (AD) is a multifactorial disease which involves both the periphery and central nervous system (CNS).
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Alzheimer's disease is associated with cerebral accumulation of amyloid-β peptide and hyperphosphorylated tau.
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Misfolded and abnormal β-sheets forms of wild-type proteins, such as cellular prion protein (PrPC) and amyloid beta (Aβ), are believed to be the vectors of neurodegenerative diseases, prion and Alzheimer's disease (AD), respectively.
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Metabolic endotoxemia is a condition in which blood lipopolysaccharide (LPS) levels are elevated, regardless of the presence of obvious infection.
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At baseline, subjects with normal vs. impaired cognition show no notable difference in microbiome diversity but several unique microbial signatures are detected in subjects with mild cognitive impairment.
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These results indicate that microbiota-mediated intestinal and systemic immune aberrations contribute to the pathogenesis of AD in ADLP APT mice, providing new insights into the relationship between the gut (colonic gene expression, gut permeability), blood (blood immune cell population) and brain (pathology) axis and AD (memory deficits).
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To understand the role of commensal gut bacteria on the progression of cognitive decline in Alzheimer’s disease via the microbiota-gut-brain axis, we isolated anti-inflammatory Bifidobacterium longum (NK46) from human gut microbiota, which potently inhibited gut microbiota endotoxin production and suppressed NF-κB activation in lipopolysaccharide (LPS)-stimulated BV-2 cells, and examined whether NK46 could simultaneously alleviate gut dysbiosis and cognitive decline in male 5xFAD-transgenic (5XFAD-Tg, 6 months-old) and aged (18 months-old) mice.
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Alzheimer's disease (AD) is still a major public health challenge without an effective treatment to prevent or stop it.
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Alzheimer's disease (AD) is a neurodegenerative disease whose various pathophysiological aspects are still being investigated.
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This paper describes the effects of the gut microbiota on the pathogenesis of Alzheimer's pathology by evaluating the current original key findings and identifying gaps in the knowledge required for validation.
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Apolipoprotein E ( APOE ) genotype is the strongest prevalent genetic risk factor for Alzheimer's disease (AD).
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Alzheimer's disease (AD) is closely related to gut microbial alteration.
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Porphyromonas gingivalis , the keystone pathogen in chronic periodontitis, was identified in the brain of Alzheimer's disease patients.
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Some observational studies have instead demonstrated that, in older individuals, frailty and Alzheimer-type dementia are associated with fecal microbiota dysbiosis, that is, reduced biodiversity and overexpression of pathobionts.
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50/100
These findings provide additional insight into gut microbial involvement in AD and add to the growing understanding of the gut-brain axis.
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Overall, we found that probiotic and selenium co-supplementation for 12 weeks to patients with AD improved cognitive function and some metabolic profiles.
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It has been suggested that exercise training and probiotic supplementation could decelerate the progress of functional and biochemical deterioration in APP/PS1 transgenic mice (APP/PS1 TG ).
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The bidirectional communication between the central nervous system (CNS) and the gut microbiota plays a pivotal role in human health.
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We report for the first time an association between altered BA profile, genetic variants implicated in AD, and cognitive changes in disease using a large multicenter study.
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This is the first study to show serum-based BA metabolites are associated with "A/T/N" AD biomarkers, providing further support for a role of BA pathways in AD pathophysiology.
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Alzheimer's disease (AD) is an increasingly common neurodegenerative disease.
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Cognitive frailty, defined as the coexistence of mild cognitive impairment symptoms and physical frailty phenotype in older persons, is increasingly considered the main geriatric condition predisposing to dementia.
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Alzheimer's disease (AD) is associated with cognitive dysfunction.
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One of the most important scientific discoveries of recent years was the disclosure that the intestinal microflora takes part in bidirectional communication between the gut and the brain.
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Alzheimer's disease is characterized by cognitive dysfunction and aging is an important predisposing factor; however, the pathological and therapeutic mechanisms are not fully understood.
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41/100
Neurovascular integrity, including cerebral blood flow (CBF) and blood-brain barrier (BBB) function, plays a major role in determining cognitive capability.
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Alzheimer's disease (AD) is a progressive neurodegenerative disease that develops insidiously and causes dementia finally.
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The gut-brain axis is a bidirectional communication network functionally linking the gut and the central nervous system (CNS).
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The gastrointestinal microbiota affects brain function, including memory and learning.
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Previous studies suggest that gut microbiota is associated with neuropsychiatric disorders, such as Parkinson's disease, amyotrophic lateral sclerosis, and depression.
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Recent studies have suggested the role of an infectious component in the pathogenesis of Alzheimer's disease (AD).
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Gut microbiota influences the central nervous system disorders such as Alzheimer's disease (AD).
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Our studies support the hypothesis that intestinal microbiota may help protect against AD, in part, by supporting the generation of select SCFAs, which interfere with the formation of toxic soluble Aβ aggregates.
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It has previously been shown that the consumption of probiotics may have beneficial effects not only on peripheral tissues but also on the central nervous system and behavior via the microbiota-gut-brain axis, raising the possibility that treatment with probiotics could be an effective therapeutic strategy for managing neurodegenerative disorders.
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The gut microbiota (GM) is a complex, evolutionarily molded ecological system, which contributes to a variety of physiological functions.
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Recent evidence suggests the commensal microbiome regulates host immunity and influences brain function; findings that have ramifications for neurodegenerative diseases.
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Abundant clinical, epidemiological, imaging, genetic, molecular and pathophysiological data together indicate that there occur an unusual inflammatory reaction and a disruption of the innate-immune signaling system in Alzheimer’s disease (AD) brain.
From across this tag
7 of the 173 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 7. The same 7 appear here every time.
- The Gut Microbiome and Alzheimer's Disease: A Growing Relationship
- Chronic neuroinflammation in rats reproduces components of the neurobiology of Alzheimer's disease
- The Gut-Brain Axis in Alzheimer’s Disease: Microbiota as a Key Contributor to Disease Pathogenesis
- Microbiota-gut-brain axis and related therapeutics in Alzheimer's disease: prospects for multitherapy and inflammation control
- Neuroprotective Effects of Clostridium butyricum against Vascular Dementia in Mice via Metabolic Butyrate
- Identification of Faecalibacterium prausnitzii strains for gut microbiome-based intervention in Alzheimer's-type dementia
- Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly