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Newest in this topic

  1. Alcohol use disorder accelerates age-related cognitive decline 2026-09-23
  2. A longitudinal study of age-related traits and cognitive function: The Collaborative Amish Aging and Memory Project (CAAMP) 2026-09-20
  3. Associations of menopause hormone therapy with late-life cognition and brain health vary by formulation and APOEε4 presence 2026-09-20

Studies

1,138 studies carry this tag.

Date range

1986 to 2026

Top journals

  • Alzheimer s & Dementia 42
  • Neurology 41
  • Journal of the American Geriatrics Society 36
  • Journal of Alzheimer's disease : JAD 33
  • Nutrients 23

437 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Enhancing memory in late-life depression: the effects of a combined psychoeducation and cognitive training program

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2011-03-01 Prevention trials

    CT may be a viable secondary prevention technique for late-life depression, a group who are at risk of further cognitive decline and progression to dementia.

  2. High blood pressure accelerates gait slowing in well-functioning older adults over 18-years of follow-up

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. Journal of the American Geriatrics Society 2011-03-01 Disparities

    High BP accelerates gait slowing in well-functioning older adults over a long period of time, even for those who control their BP or develop hypertension later in life.

  3. Gait stability and variability measures show effects of impaired cognition and dual tasking in frail people

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Journal of neuroengineering and rehabilitation 2011-01-17 Clinical safety

    The observed trunk adaptations were a consistent instability factor.

  4. Adherence to a Mediterranean-type dietary pattern and cognitive decline in a community population

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. The American journal of clinical nutrition 2010-12-22 Prevention trials

    The Mediterranean dietary pattern as captured by the MedDiet scoring system may reduce the rate of cognitive decline with older age.

  5. Interim follow-up of a randomized controlled trial comparing Chinese style mind body (Tai Chi) and stretching exercises on cognitive function in subjects at risk of progressive cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. International journal of geriatric psychiatry 2010-12-09 Prevention and risk

    We reported the interim findings of a randomized controlled trial (RCT) to examine the effects of a mind body physical exercise (Tai Chi) on cognitive function in Chinese subjects at risk of cognitive decline.

  6. Timing of hormone therapy and dementia: the critical window theory revisited

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Annals of neurology 2010-11-12 Brain tissue and pathology

    Although previous research has shown that initiation of postmenopausal estrogen hormone therapy (HT) in late life increases risk of dementia, animal studies and some observational studies have suggested that midlife use of HT may be beneficial; however, this has not been rigorously investigated in large population-based studies.

  7. The Short FES-I is a valid measure to assess fear of falling in frail older adults with and without cognitive impairment, yet it may show floor effects in higher functioning older people.

  8. Oophorectomy, menopause, estrogen treatment, and cognitive aging: clinical evidence for a window of opportunity

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Brain research 2010-10-18 Brain tissue and pathology

    The neuroprotective effects of estrogen have been demonstrated consistently in cellular and animal studies but the evidence in women remains conflicted.

  9. Premorbid cognitive leisure independently contributes to cognitive reserve in multiple sclerosis

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Neurology 2010-10-01 Brain scans and imaging

    Also, patients with MS who engaged in more cognitive leisure were able to withstand more severe brain atrophy at a given cognitive status.

  10. Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial

    ✓ Peer-reviewed alzhub usefulness score 78 out of 100. PloS one 2010-09-08 Risk factors

    The mean rate of brain atrophy per year was 0.76% [95% CI, 0.63-0.90] in the active treatment group and 1.08% [0.94-1.22] in the placebo group (P = 0.001).

  11. Treatment of cardiovascular risk factors to prevent cognitive decline and dementia: a systematic review

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Vascular health and risk management 2010-09-07 Treatments

    The evidence of a preventive treatment effect aimed at vascular risk factors on cognitive decline and dementia in later life is scarce and mostly based on secondary outcome parameters.

  12. Progression of brain atrophy and cognitive decline in diabetes mellitus: a 3-year follow-up

    ✓ Peer-reviewed alzhub usefulness score 74 out of 100. Neurology 2010-09-01 Vascular contributions

    Our data show that elderly patients with DM without dementia have accelerated progression of brain atrophy with significant consequences in cognition compared to subjects without DM.

  13. The Sydney Memory and Ageing Study (MAS): methodology and baseline medical and neuropsychiatric characteristics of an elderly epidemiological non-demented cohort of Australians aged 70-90 years

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. International psychogeriatrics 2010-07-19 Mild cognitive impairment

    Cognitive complaints are common in the elderly, and nearly one in three meet criteria for MCI.

  14. Use of anticholinergics and the risk of cognitive impairment in an African American population

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Neurology 2010-07-01 Caregiving

    Limiting the clinical use of definite anticholinergics may reduce the incidence of cognitive impairment among African Americans.

  15. Vitamin D and risk of cognitive decline in elderly persons

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Archives of internal medicine 2010-07-01 Prevention and risk

    Low levels of vitamin D were associated with substantial cognitive decline in the elderly population studied over a 6-year period, which raises important new possibilities for treatment and prevention.

  16. Systematic review: factors associated with risk for and possible prevention of cognitive decline in later life

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Annals of internal medicine 2010-06-14 Prevention trials

    An overall rating of the quality of evidence was assigned by using the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) criteria.

  17. Interventions to reduce cognitive decline in aging

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of psychosocial nursing and mental health services 2010-05-01 Prevention trials

    As the population ages, risks for cognitive decline threaten independence and quality of life for older adults and present challenges to the health care system.

  18. Blueberry supplementation improves memory in older adults

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Journal of agricultural and food chemistry 2010-04-01 How common it is

    The prevalence of dementia is increasing with expansion of the older adult population.

  19. The older adult driver with cognitive impairment: "It's a very frustrating life"

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. JAMA 2010-04-01 Clinical safety

    Although automobiles remain the transportation of choice for many older adults, late-life cognitive impairment and dementia often impair the ability to drive safely.

  20. Effects of the dietary approaches to stop hypertension diet, exercise, and caloric restriction on neurocognition in overweight adults with high blood pressure

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. Hypertension (Dallas, Tex. : 1979) 2010-03-19 Risk factors

    High blood pressure increases the risks of stroke, dementia, and neurocognitive dysfunction.

  21. Occlusion and brain function: mastication as a prevention of cognitive dysfunction

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of oral rehabilitation 2010-03-02 Prevention and risk

    Research in animals and humans has shown that mastication maintains cognitive function in the hippocampus, a brain area important for learning and memory.

  22. Cognitive leisure activities and their role in preventing dementia: a systematic review

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. International journal of evidence-based healthcare 2010-03-01 Prevention and risk

    Because of the heterogeneity of populations and interventions, meta-analyses were not possible and results are presented in narrative form.

  23. Early intervention for cognitive decline: can cognitive training be used as a selective prevention technique?

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. International psychogeriatrics 2010-02-22 Prevention trials

    CT offers promise as a preventive therapeutic technique in healthy older adults and particularly as a secondary prevention method for "at risk" groups.

  24. Association between acute care and critical illness hospitalization and cognitive function in older adults

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. JAMA 2010-02-01 Getting a diagnosis

    During a mean (SD) follow-up of 6.1 (3.2) years, 1601 participants had no hospitalization, 1287 had 1 or more noncritical illness hospitalizations, and 41 had 1 or more critical illness hospitalizations.

  25. Cognitive exercise and its role in cognitive function in older adults

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Current psychiatry reports 2010-02-01 Prevention trials

    Converging lines of research indicate that complex mental activity is associated with reduced dementia risk.

  26. Diet and neurocognition: review of evidence and methodological considerations

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Current aging science 2010-02-01 Prevention trials

    The relationship between diet and cognitive function has been a topic of increasing interest, as numerous studies have shown that variations in dietary practices and nutrient intake may protect against age-related cognitive decline, as well as the development of dementia and Alzheimer's Disease (AD).

  27. Extraskeletal effects of vitamin D in older adults: cardiovascular disease, mortality, mood, and cognition

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. The American journal of geriatric pharmacotherapy 2010-02-01 Clinical safety

    Forty-two case-control, cohort, and randomized trials were identified and included in the review.

  28. Healthy brain aging: role of exercise and physical activity

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Clinics in geriatric medicine 2010-02-01 Treatments

    There is increasing evidence to suggest that physical activity has a protective effect on brain functioning in older people.

  29. Hospital characteristics associated with feeding tube placement in nursing home residents with advanced cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. JAMA 2010-02-01 End-of-life care

    Among nursing home residents with advanced cognitive impairment admitted to acute care hospitals, for-profit ownership, larger hospital size, and greater ICU use was associated with increased rates of feeding tube insertion, even after adjusting for patient-level characteristics.

  30. When does brain aging accelerate? Dangers of quadratic fits in cross-sectional studies

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. NeuroImage 2010-01-25 Hippocampus size on brain scans

    Many brain structures show a complex, non-linear pattern of maturation and age-related change.

  31. Aerobic exercise improves cognition for older adults with glucose intolerance, a risk factor for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Journal of Alzheimer's disease : JAD 2010-01-01 Prevention and risk

    Impaired glucose regulation is a defining characteristic of type 2 diabetes mellitus (T2DM) pathology and has been linked to increased risk of cognitive impairment and dementia.

  32. Age and education effects and norms on a cognitive test battery from a population-based cohort: the Monongahela-Youghiogheny Healthy Aging Team

    ✓ Peer-reviewed alzhub usefulness score 42 out of 100. Aging & mental health 2010-01-01 Cognitive tests and assessment

    Performance on cognitive tests can be affected by age, education, and also selection bias.

  33. Effects of aerobic exercise on mild cognitive impairment: a controlled trial

    ✓ Peer-reviewed alzhub usefulness score 77 out of 100. Archives of neurology 2010-01-01 Treatments

    Six months of high-intensity aerobic exercise had sex-specific effects on cognition, glucose metabolism, and hypothalamic-pituitary-adrenal axis and trophic activity despite comparable gains in cardiorespiratory fitness and body fat reduction.

  34. Mediterranean diet and cognitive function in older adults

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Current opinion in clinical nutrition and metabolic care 2010-01-01 Prevention and risk

    A high adherence to the Mediterranean diet has been associated with slower cognitive decline, with reduced risk of mild cognitive impairment conversion to Alzheimer's disease and with reduced risk of Alzheimer's disease.

  35. Nutraceutical properties of Mediterranean diet and cognitive decline: possible underlying mechanisms

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Journal of Alzheimer's disease : JAD 2010-01-01 Mild cognitive impairment

    Recent prospective studies provided evidence that higher adherence to a Mediterranean-type diet could be associated with slower cognitive decline, reduced risk of progression from mild cognitive impairment to Alzheimer's disease (AD), reduced risk of AD, and decreased mortality in AD patients.

  36. Outcome over seven years of healthy adults with and without subjective cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2010-01-01 Prevention and risk

    Follow-up occurred during a mean period of 6.8 +/- 3.4 years, and subjects had a mean of 2.9 +/- 1.6 follow-up visits.

  37. Physical exercise, aging, and mild cognitive impairment: a population-based study

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Archives of neurology 2010-01-01 Prevention and risk

    In this population-based case-control study, any frequency of moderate exercise performed in midlife or late life was associated with a reduced odds of having MCI.

  38. Ginkgo biloba for preventing cognitive decline in older adults: a randomized trial

    ✓ Peer-reviewed alzhub usefulness score 79 out of 100. JAMA 2009-12-01 Genetics

    Compared with placebo, the use of G. biloba, 120 mg twice daily, did not result in less cognitive decline in older adults with normal cognition or with mild cognitive impairment.

  39. Action of estrogens in the aging brain: dementia and cognitive aging

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Biochimica et biophysica acta 2009-11-12 Treatments

    Menopause is associated with sharp declines in concentrations of circulating estrogens.

  40. Systematic review of health behavioral risks and cognitive health in older adults

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. International psychogeriatrics 2009-11-03 Prevention and risk

    The review demonstrates accumulating evidence supporting health behavioral effects in reducing the risk of cognitive decline and dementia.

  41. Olive oil and cognition: results from the three-city study

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Dementia and geriatric cognitive disorders 2009-10-30 Prevention trials

    This olive oil-cognition association needs to be confirmed by further studies.

  42. The neurobiology of brain and cognitive reserve: mental and physical activity as modulators of brain disorders

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Progress in neurobiology 2009-10-09 Prevention and risk

    The concept of 'cognitive reserve', and a broader theory of 'brain reserve', were originally proposed to help explain epidemiological data indicating that individuals who engaged in higher levels of mental and physical activity via education, occupation and recreation, were at lower risk of developing Alzheimer's disease and other forms of dementia.

  43. Long-term exposure to traffic-related particulate matter impairs cognitive function in the elderly

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Environmental research 2009-09-04 Mild cognitive impairment

    Animal studies have suggested that fine particulate matter (PM) can translocate from the upper respiratory tract to the brain and cause brain inflammation.

  44. Effects of age, dietary, and behavioral enrichment on brain mitochondria in a canine model of human aging

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Experimental neurology 2009-08-22 Prevention trials

    Dogs develop cognitive decline and a progressive accumulation of oxidative damage.

  45. Vitamin D and cognitive performance in adults: a systematic review

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. European journal of neurology 2009-07-29 Clinical safety

    Chronic low serum 25-hydroxyvitamin D (25OHD) concentrations are common in adults and are associated with numerous non-skeletal diseases.

  46. Cognitive impairment predicts poststroke death in long-term follow-up

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Journal of neurology, neurosurgery, and psychiatry 2009-07-19 Cognitive tests and assessment

    Whether deficits in specific cognitive domains are associated with long-term survival in patients with ischaemic stroke is not known in detail.

  47. Angiotensin-converting enzyme inhibitors and cognitive decline in older adults with hypertension: results from the Cardiovascular Health Study

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Archives of internal medicine 2009-07-01 Prevention and risk

    These results should be confirmed with a randomized clinical trial of a centrally active ACE inhibitor in the prevention of cognitive decline and dementia.

  48. Association between late-life social activity and motor decline in older adults

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. Archives of internal medicine 2009-06-01 Brain tissue and pathology

    Loss of motor function is a common consequence of aging, but little is known about the factors that predict idiopathic motor decline.

  49. Several factors influenced attrition in a population-based elderly cohort: neurological disorders in Central Spain Study

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Journal of clinical epidemiology 2009-05-26 Disparities

    These findings on participants who are at high risk of dropout may be useful in the planning phase of future prospective studies.

  50. Periodontitis is associated with cognitive impairment among older adults: analysis of NHANES-III

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Journal of neurology, neurosurgery, and psychiatry 2009-05-05 Risk factors

    Further exploration of relationships between oral health and cognition is warranted.

From across this tag

9 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.

All topic tags with their study counts