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Newest in this topic

  1. Alcohol use disorder accelerates age-related cognitive decline 2026-09-23
  2. A longitudinal study of age-related traits and cognitive function: The Collaborative Amish Aging and Memory Project (CAAMP) 2026-09-20
  3. Associations of menopause hormone therapy with late-life cognition and brain health vary by formulation and APOEε4 presence 2026-09-20

Studies

1,138 studies carry this tag.

Date range

1986 to 2026

Top journals

  • Alzheimer s & Dementia 42
  • Neurology 41
  • Journal of the American Geriatrics Society 36
  • Journal of Alzheimer's disease : JAD 33
  • Nutrients 23

437 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. The relationship between obesity and cognitive health and decline

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. The Proceedings of the Nutrition Society 2017-09-11 Prevention and risk

    The relationship between obesity and cognitive impairment is important given the globally ageing population in whom cognitive decline and neurodegenerative disorders will carry grave individual, societal and financial burdens.

  2. Association of Vision Loss With Cognition in Older Adults

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. JAMA ophthalmology 2017-09-01 Disparities

    Sample weights were used to ensure result generalizability.

  3. Vitamin C Status and Cognitive Function: A Systematic Review

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Nutrients 2017-08-30 Cognitive tests and assessment

    Vitamin C plays a role in neuronal differentiation, maturation, myelin formation and modulation of the cholinergic, catecholinergic, and glutaminergic systems.

  4. Intradialytic Cognitive and Exercise Training May Preserve Cognitive Function

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. Kidney international reports 2017-08-19 Prevention trials

    Preliminary findings of our pilot study suggested that cognitive decline in psychomotor speed and executive function is possibly prevented by intradialytic CT and ET.

  5. Mediterranean diet and cognitive health: Initial results from the Hellenic Longitudinal Investigation of Ageing and Diet

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. PloS one 2017-08-01 Prevention and risk

    Our results suggest that adherence to the MeDi is associated with better cognitive performance and lower dementia rates in Greek elders.

  6. Advancing age increases the risk for diseases and health concerns like cognitive decline, constituting a major public health challenge.

  7. Our findings suggest that older patients with reduced preoperative cognitive functions or who develop postoperative delirium are at risk of developing dementia within 5 years after cardiac surgery.

  8. Metabolomics and cognition in African American adults in midlife: the atherosclerosis risk in communities study

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Translational psychiatry 2017-07-18 Long-term cohort studies

    Clinical studies have shown alterations in metabolic profiles when patients with mild cognitive impairment and Alzheimer's disease dementia were compared to cognitively normal subjects.

  9. Effects of computerized cognitive training on neuroimaging outcomes in older adults: a systematic review

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. BMC geriatrics 2017-07-10 Prevention trials

    Of all studies included in this systematic review, results from the highest quality studies, which were two randomized controlled trials, demonstrated that multi-domain CCT could lead to increases in hippocampal functional connectivity.

  10. The Association between the Mediterranean Dietary Pattern and Cognitive Health: A Systematic Review

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. Nutrients 2017-06-28 Prevention and risk

    The ageing population is accompanied by increased rates of cognitive decline and dementia.

  11. Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia

    ✓ Peer-reviewed alzhub usefulness score 81 out of 100. The Cochrane database of systematic reviews 2017-06-15 Cognitive tests and assessment

    Prevention of cognitive impairment and dementia is an important public health goal.

  12. Lifestyle Modulators of Neuroplasticity: How Physical Activity, Mental Engagement, and Diet Promote Cognitive Health during Aging

    ✓ Peer-reviewed alzhub usefulness score 44 out of 100. Neural plasticity 2017-06-12 Prevention and risk

    The number of the elderly across the globe will approximate 2.1 billion by 2050.

  13. Physical Exercise with Music Reduces Gray and White Matter Loss in the Frontal Cortex of Elderly People: The Mihama-Kiho Scan Project

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Frontiers in aging neuroscience 2017-06-07 Prevention trials

    However, the brain plasticity associated with these proposed benefits of combined therapy has not yet been investigated in elderly subjects.

  14. Inflammatory Biomarkers Predict Domain-Specific Cognitive Decline in Older Adults

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. The journals of gerontology. Series A, Biological sciences and medical sciences 2017-06-01 Disease mechanisms

    In particular, systemic inflammation, vascular inflammation, and altered endothelial function may play roles in domain-specific cognitive decline of nondemented individuals.

  15. Cognitive decline in normal aging and its prevention: a review on non-pharmacological lifestyle strategies

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Clinical interventions in aging 2017-05-25 Prevention trials

    The purpose of this study is to examine the effects of the selected non-pharmacological lifestyle activities on the delay of cognitive decline in normal aging.

  16. Physical activity improves cognition: possible explanations

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Biogerontology 2017-05-10 Prevention trials

    Good cognitive abilities (CA) enable autonomy, improve social inclusion and act preventively.

  17. Sedentary behavior as a risk factor for cognitive decline? A focus on the influence of glycemic control in brain health

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Alzheimer's & dementia (New York, N. Y.) 2017-05-02 Prevention and risk

    Cognitive decline leading to dementia represents a global health burden.

  18. Hearing Impairment and Incident Dementia and Cognitive Decline in Older Adults: The Health ABC Study

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. The journals of gerontology. Series A, Biological sciences and medical sciences 2017-05-01 Prevention and risk

    HI is associated with increased risk of developing dementia in older adults.

  19. Improvement of Cognitive Function after Computer-Based Cognitive Training in Early Stage of Alzheimer's Dementia

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Dementia and neurocognitive disorders 2017-03-31 Prevention trials

    Computer-based cognitive training might have beneficial effects on the general cognitive functions in early stage of Alzheimer's dementia.

  20. The impact of individual Cognitive Stimulation Therapy (iCST) on cognition, quality of life, caregiver health, and family relationships in dementia: A randomised controlled trial

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. PLoS medicine 2017-03-28 Cognitive tests and assessment

    Cognitive stimulation therapy (CST) is a well-established group psychosocial intervention for people with dementia.

  21. The role of cognitive activity in cognition protection: from Bedside to Bench

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Translational neurodegeneration 2017-03-28 Prevention trials

    The positive effects of cognitive activity is closely related with neural plasticity, neurotrophin, neurotransmitter and neuromodulator signaling pathway changes.

  22. Researchers conducted a trial to test the effect of omega 3 polyunsaturated fatty acid supplementation and a multidomain intervention, alone or in combination, compared with placebo, on cognitive decline in elderly adults with memory complaints.

  23. We also determined the extent to which sex, educational attainment, and apolipoprotein E ε4 allele (APOE*4) carrier status were associated with decline.

  24. Potentially modifiable lifestyle factors, cognitive reserve, and cognitive function in later life: A cross-sectional study

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. PLoS medicine 2017-03-21 Prevention and risk

    Cross-sectional associations support the view that enhancing cognitive reserve may benefit cognition, and maintenance of cognitive health may be supported by a healthy and active lifestyle, in later life.

  25. Tuning Up the Old Brain with New Tricks: Attention Training via Neurofeedback

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Frontiers in aging neuroscience 2017-03-13 Prevention trials

    Neurofeedback (NF) is a form of biofeedback that uses real-time (RT) modulation of brain activity to enhance brain function and behavioral performance.

  26. Blood cholesterol in late-life and cognitive decline: a longitudinal study of the Chinese elderly

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Molecular neurodegeneration 2017-03-07 Cognitive tests and assessment

    We thus examined whether higher blood cholesterol concentrations were associated with faster cognitive decline in a community-based longitudinal study of Chinese elderly.

  27. Cognitively normal elderly individuals who engage in specific mentally stimulating activities even in late life have a decreased risk of incident MCI.

  28. Association of Delirium With Cognitive Decline in Late Life: A Neuropathologic Study of 3 Population-Based Cohort Studies

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. JAMA psychiatry 2017-03-01 Caregiving

    There were 987 participants (290 from Vantaa 85+, 241 from the Cambridge City Over-75s Cohort, and 456 from the Cognitive Function and Ageing Study) with neuropathologic data; mean (SD) age at death was 90 (6.4) years, including 682 women (69%).

  29. Physical Frailty, Cognitive Impairment, and the Risk of Neurocognitive Disorder in the Singapore Longitudinal Ageing Studies

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. The journals of gerontology. Series A, Biological sciences and medical sciences 2017-03-01 Cognitive tests and assessment

    The independent and combined effects of physical and cognitive domains of frailty in predicting the development of mild cognitive impairment (MCI) or dementia are not firmly established.

  30. Existing neurocomputational and empirical data link deficient neuromodulation of the fronto-parietal and hippocampal-striatal circuitries with aging-related increase in processing noise and declines in various cognitive functions.

  31. n-3 Fatty acids, Mediterranean diet and cognitive function in normal aging: A systematic review

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Experimental gerontology 2017-02-14 Prevention trials

    Studies suggest that n-3 fatty acids in the diet and adherence to the MedDiet are beneficial in slowing age-related cognitive decline.

  32. Relationship between chewing ability and cognitive impairment in the rural elderly

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Archives of gerontology and geriatrics 2017-02-11 Disparities

    Our findings suggest that poor chewing ability is associated with cognitive impairment or dementia in the elderly living in rural area.

  33. Handgrip strength as a means of monitoring progression of cognitive decline - A scoping review

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Ageing research reviews 2017-02-08 Mild cognitive impairment

    Cognitive decline in older adults contributes to reduced ability to perform daily tasks and continued disuse leads to muscle weakness and potentiates functional loss.

  34. Sex differences in the association between AD biomarkers and cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Brain imaging and behavior 2017-02-01 Hippocampus size on brain scans

    Women are disproportionately affected by Alzheimer's disease (AD) in terms of both disease prevalence and severity.

  35. Cognitive Decline and Its Risk Factors in Prevalent Hemodialysis Patients

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. American journal of kidney diseases : the official journal of the National Kidney Foundation 2017-01-26 Disparities

    Prevalent hemodialysis patients demonstrate significant cognitive decline, particularly within tests of executive function.

  36. Successfully assisting older adults to maintain or improve cognitive function, particularly when they are dealing with neurodegenerative disorders such as Alzheimer's disease (AD), remains a major challenge.

  37. The Built Environment and Cognitive Disorders: Results From the Cognitive Function and Ageing Study II

    ✓ Peer-reviewed alzhub usefulness score 58 out of 100. American journal of preventive medicine 2017-01-09 Disparities

    Non-linear associations between features of land use and cognitive impairment were confirmed in this new cohort of older people in England.

  38. Randomized trial on the effects of a combined physical/cognitive training in aged MCI subjects: the Train the Brain study

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Scientific reports 2017-01-03 Cognitive tests and assessment

    Age-related cognitive impairment and dementia are an increasing societal burden.

  39. A 24-Week Multi-Modality Exercise Program Improves Executive Control in Older Adults with a Self-Reported Cognitive Complaint: Evidence from the Antisaccade Task

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Prevention trials

    Exercise programs involving aerobic and resistance training (i.e., multiple-modality) have shown promise in improving cognition and executive control in older adults at risk, or experiencing, cognitive decline.

  40. Cognitive Changes with Omega-3 Polyunsaturated Fatty Acids in Non-Demented Older Adults with Low Omega-3 Index

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. The journal of nutrition, health & aging 2017-01-01 Treatments

    We found some evidence that n-3 PUFAs might be beneficial for the maintenance of executive functioning in older adults at risk of dementia with low omega-3 index, but this exploratory finding requires further confirmation.

  41. Do Hearing Aids Influence Behavioral and Psychological Symptoms of Dementia and Quality of Life in Hearing Impaired Alzheimer's Disease Patients and Their Caregivers?

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Treatments

    These findings do not provide evidence of improvement in behavioral symptoms, functional status, or QoL of hearing impaired AD patients and their caregivers after 6 months of HA use.

  42. Tailored and Adaptive Computerized Cognitive Training in Older Adults at Risk for Dementia: A Randomized Controlled Trial

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Journal of Alzheimer's disease : JAD 2017-01-01 Prevention trials

    Home-based CCT with adaptive difficulty and personal tailoring appears superior to more generic CCT in relation to both cognitive and non-cognitive outcomes.

  43. The relevance of nutrition for the concept of cognitive frailty

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Current opinion in clinical nutrition and metabolic care 2017-01-01 Prevention trials

    Physical and cognitive frailty are interrelated and synergistic syndromes more frequently seen in old age, which represent intermediate stages between aging successfully and disability.

  44. Computer-Based Cognitive Training in Aging

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Frontiers in aging neuroscience 2016-12-20 Prevention trials

    At present there is a rapid growth of aging population groups worldwide, which brings about serious economic and social problems.

  45. Cognitive Aging and the Hippocampus in Older Adults

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Frontiers in aging neuroscience 2016-12-08 Cognitive tests and assessment

    The hippocampus is one of the most well studied structures in the human brain.

  46. Falls, Cognitive Impairment, and Gait Performance: Results From the GOOD Initiative

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Journal of the American Medical Directors Association 2016-11-30 Clinical safety

    These findings suggest that non-AD, but not AD dementia, is associated with increased falls in comparison with CHIs.

  47. Cognitive Training in the Elderly: Bottlenecks and New Avenues

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of cognitive neuroscience 2016-11-29 Prevention trials

    Development of measures to preserve cognitive function or even reverse cognitive decline in the ever-growing elderly population is the focus of many research and commercial efforts.

  48. The expected outcome is to ensure the continuity of care from clinical practice to the patient's home, enabling also cost effectiveness and the empowerment of patient and caregiver in the care process, positively impacting on their quality of life.

  49. Can mindfulness-based interventions influence cognitive functioning in older adults? A review and considerations for future research

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Aging & mental health 2016-11-09 Prevention trials

    We conclude that eight-week MBI for older adults are feasible, but results on cognitive improvement are inconclusive due a limited number of studies, small sample sizes, and a high risk of bias.

  50. Perceived Stress and Cognitive Decline in Different Cognitive Domains in a Cohort of Older African Americans

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2016-10-11 Disparities

    Research indicates that stress is linked to cognitive dysfunction.

From across this tag

10 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

All topic tags with their study counts