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[Use of modern classification systems for complex diagnostics of Alzheimer's disease]
Y A Zorkina, I O Morozova, O V Abramova, A G Ochneva, O A Gankina, A V Andryushenko, M V Kurmyshev, G P Kostyuk et al.. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2024
Topic: Plasma and spinal-fluid biomarkers
The preliminary diagnosis of AD was made in 3 patients (5%). As a result of the study of protein content in the CSF, signs of AD were detected in 48 (75%) people. The findings suggest that the diagnosis of AD is made 10-14 times less frequently than it should be according to the World Health Organization data. The discrepancy between clinical diagnosis and laboratory findings is confirmed by our study. Differences in the therapy of dementias and the development of new drugs targeting specific links in the pathogenesis of different types of dementias require accurate and complete diagnosis of dementias, especially AD, as the most common type of dementia.
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APA 7th
Zorkina, Y. A., Morozova, I. O., Abramova, O. V., Ochneva, A. G., Gankina, O. A., Andryushenko, A. V., et al. (2024). [Use of modern classification systems for complex diagnostics of Alzheimer's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. https://doi.org/10.17116/jnevro2024124011121
Vancouver
Zorkina YA, Morozova IO, Abramova OV, Ochneva AG, Gankina OA, Andryushenko AV, et al. [Use of modern classification systems for complex diagnostics of Alzheimer's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2024. doi:10.17116/jnevro2024124011121. PMID: 38261294.
BibTeX
@article{zorkina2024-38261294,
author = {Zorkina, Y A and Morozova, I O and Abramova, O V and Ochneva, A G and Gankina, O A and Andryushenko, A V and Kurmyshev, M V and Kostyuk, G P and others},
title = {{[Use of modern classification systems for complex diagnostics of Alzheimer's disease]}},
journal = {Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova},
year = {2024},
doi = {10.17116/jnevro2024124011121},
pmid = {38261294},
url = {https://doi.org/10.17116/jnevro2024124011121}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
Key findings
- The preliminary diagnosis of AD was made in 3 patients (5%).
- As a result of the study of protein content in the CSF, signs of AD were detected in 48 (75%) people.
- The findings suggest that the diagnosis of AD is made 10-14 times less frequently than it should be according to the World Health Organization data.
- The discrepancy between clinical diagnosis and laboratory findings is confirmed by our study.
- Differences in the therapy of dementias and the development of new drugs targeting specific links in the pathogenesis of different types of dementias require accurate and complete diagnosis of dementias, especially AD, as the most common type of dementia.
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Study details
- Participants64
- Evidence strengthLow
How this study scored 50/100
Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multi-centre collaboration and free to read, so those were left out: it earned 28 of the 56 points we could judge it on, which is 50 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2024 — within 3 year(s) of the newest study here |
| Sample size | 1 / 4 | 64 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 38261294) |
| Free to read | — / 2 | Access not recorded — left out of this score |
| Points | 28 / 56 | Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 28 of the 56 points we could judge it on is 50 out of 100. |
| Total | 50 / 100 | — |
What each of these 20 components measures, and what this score is not →
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