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Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research
Ali BH, Blunden G, Tanira MO, Nemmar A.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007-09-18
Topic: Brain proteins, microglia and lab models
Plain-language summary
Ginger (Zingiber officinale Roscoe, Zingiberacae) is a medicinal plant that has been widely used in Chinese, Ayurvedic and Tibb-Unani herbal medicines all over the world, since antiquity, for a wide array of unrelated ailments that include arthritis, rheumatism, sprains, muscular aches, pains, sore throats, cramps, constipation, indigestion, vomiting, hypertension, dementia, fever, infectious diseases and helminthiasis. Currently, there is a renewed interest in ginger, and several scientific investigations aimed at isolation and identification of active constituents of ginger, scientific verification of its pharmacological actions and of its constituents, and verification of the basis of the use of ginger in some of several diseases and conditions. This article aims at reviewing the most salient recent reports on these investigations. The main pharmacological actions of ginger and compounds isolated therefrom include immuno-modulatory, anti-tumorigenic, anti-inflammatory, anti-apoptotic, anti-hyperglycemic, anti-lipidemic and anti-emetic actions. Ginger is a strong anti-oxidant substance and may either mitigate or prevent generation of free radicals. It is considered a safe herbal medicine with only few and insignificant adverse/side effects. More studies are required in animals and humans on the kinetics of ginger and its constituents and on the effects of their consumption over a long period of time.
What this study adds
Evidence grade: Low
This is a narrative review. This review of ginger notes it has been used traditionally for many ailments including dementia and describes its pharmacological actions such as anti-inflammatory and anti-oxidant effects. It states that more studies are required in animals and humans on the kinetics of ginger and its constituents and the effects of their consumption.
Taken from this record’s own fields, not from reading the paper. The grade is assigned from the abstract’s wording; what that means.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Ali, B. H., Blunden, G., Tanira, M. O., & Nemmar, A. (2008). Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. https://doi.org/10.1016/j.fct.2007.09.085
Vancouver
Ali BH, Blunden G, Tanira MO, Nemmar A. Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2008. doi:10.1016/j.fct.2007.09.085. PMID: 17950516.
BibTeX
@article{ali2008-17950516,
author = {Ali, B. H. and Blunden, G. and Tanira, M. O. and Nemmar, A.},
title = {{Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research}},
journal = {Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
year = {2008},
doi = {10.1016/j.fct.2007.09.085},
pmid = {17950516},
url = {https://doi.org/10.1016/j.fct.2007.09.085}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
Key findings
- This article aims at reviewing the most salient recent reports on these investigations.
- The main pharmacological actions of ginger and compounds isolated therefrom include immuno-modulatory, anti-tumorigenic, anti-inflammatory, anti-apoptotic, anti-hyperglycemic, anti-lipidemic and anti-emetic actions.
- Ginger is a strong anti-oxidant substance and may either mitigate or prevent generation of free radicals.
- It is considered a safe herbal medicine with only few and insignificant adverse/side effects.
- More studies are required in animals and humans on the kinetics of ginger and its constituents and on the effects of their consumption over a long period of time.
Why it matters
This review of ginger notes it has been used traditionally for many ailments including dementia and describes its pharmacological actions such as anti-inflammatory and anti-oxidant effects. It states that more studies are required in animals and humans on the kinetics of ginger and its constituents and the effects of their consumption.
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Study details
- Evidence strengthLow
How this study scored 48/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomized / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association) |
| Journal's citation record | 3 / 4 | Food and Chemical Toxicology: journal h-index 260 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2008 — within 20 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomized / blinded | 0 / 2 | No randomization or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 7 / 7 | Cited 1,594 times (OpenAlex, 2026-10-10) |
| Citations per year | 5 / 5 | 79.7 citations a year over 20 year(s) since 2008 |
| Impact for its field and year | 4 / 6 | Cited 15.9× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 4 / 4 | Cited 259 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Abderrahim Nemmar: h-index 55 (OpenAlex, whole career) |
| Institution's track record | 0 / 3 | University of Portsmouth: institution h-index 584 (OpenAlex) |
| Multicenter collaboration | 1 / 3 | OpenAlex lists 3 institution(s) in 3 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 17950516) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 48 / 100 | — |
What each of these 20 components measures, and what this score is not →
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