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41/100

✓ Peer-reviewed alzhub usefulness score 41 out of 100. Cognitive tests and assessment

Topic: Amyloid, tau and blood-test diagnosis

Objective To test the hypothesis that semantic impairment is present in both patients with dementia with Lewy bodies (DLB) and those with dementia of Alzheimer's type (DAT). Methods A comprehensive battery of neuropsychological tasks designed to assess semantic memory, visuoperceptual function, verbal fluency, and recognition memory was given to groups of patients with DLB (n=10), DAT (n=10) matched pairwise for age and mini mental state examination (MMSE), and age matched normal controls (n=15). Results Both DLB and DAT groups exhibited impaired performance across the range of tasks designed to assess semantic memory.

Cite this study APA, Vancouver, BibTeX · download .bib or .ris

APA 7th

Lambon Ralph, M. A., Powell, J., Howard, D., Whitworth, A. B., Garrard, P., & Hodges, JR. (2001). Semantic memory is impaired in both dementia with Lewy bodies and dementia of Alzheimer's type: a comparative neuropsychological study and literature review. Journal of neurology, neurosurgery, and psychiatry. https://doi.org/10.1136/jnnp.70.2.149

Vancouver

Lambon Ralph MA, Powell J, Howard D, Whitworth AB, Garrard P, Hodges JR. Semantic memory is impaired in both dementia with Lewy bodies and dementia of Alzheimer's type: a comparative neuropsychological study and literature review. Journal of neurology, neurosurgery, and psychiatry. 2001. doi:10.1136/jnnp.70.2.149. PMID: 11160461.

BibTeX

@article{lambonralph2001-11160461,
  author  = {Lambon Ralph, M. A. and Powell, J. and Howard, D. and Whitworth, A. B. and Garrard, P. and Hodges, JR.},
  title   = {{Semantic memory is impaired in both dementia with Lewy bodies and dementia of Alzheimer's type: a comparative neuropsychological study and literature review}},
  journal = {Journal of neurology, neurosurgery, and psychiatry},
  year    = {2001},
  doi     = {10.1136/jnnp.70.2.149},
  pmid    = {11160461},
  url     = {https://doi.org/10.1136/jnnp.70.2.149}
}

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Key findings

Methods A comprehensive battery of neuropsychological tasks designed to assess semantic memory, visuoperceptual function, verbal fluency, and recognition memory was given to groups of patients with DLB (n=10), DAT (n=10) matched pairwise for age and mini mental state examination (MMSE), and age matched normal controls (n=15).
Results Both DLB and DAT groups exhibited impaired performance across the range of tasks designed to assess semantic memory.
Whereas patients with DAT showed equivalent comprehension of written words and picture stimuli, patients with DLB demonstrated more severe semantic deficits for pictures than words.
As in previous studies, patients with DLB but not those with DAT were found to have impaired visuoperceptual functioning.

Why it matters

In small groups of patients with dementia with Lewy bodies and dementia of Alzheimer's type matched for age and MMSE, both groups showed impaired performance on tasks of semantic memory. This describes similarities in cognitive impairment between the two dementias, but it does not test any treatment or prevention.

Study details

Evidence strengthLow

How this study scored 41/100

Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomized / blinded because the record does not state it.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Journal of neurology, neurosurgery, and psychiatry)
Journal's citation record	3 / 4	Journal of Neurology Neurosurgery & Psychiatry: journal h-index 336 (OpenAlex, 2026-10-29)
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	1 / 5	Rated “low” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	1 / 5	2001 — older than 20 years, still counted
Sample size	0 / 4	Participant count not stated — scores zero (not stated in the record — scored 0)
Effect reported	0 / 3	No effect size reported — scores zero (not stated in the record — scored 0)
Studied in people	0 / 3	Not stated whether this was studied in people — scores zero (not stated in the record — scored 0)
Randomized / blinded	0 / 2	No randomization or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	5 / 7	Cited 178 times (OpenAlex, 2026-10-10)
Citations per year	2 / 5	6.6 citations a year over 27 year(s) since 2001
Impact for its field and year	3 / 6	Cited 4.7× the average for papers of its field and year (OpenAlex FWCI)
Cited by studies here	1 / 6	Cited by 2 other studies in this library
Still being cited	1 / 4	Cited 8 times in 2024–2026 (2026 still in progress; OpenAlex)
Senior author's track record	4 / 4	Last-listed author Matthew A. Lambon Ralph: h-index 105 (OpenAlex, whole career)
Institution's track record	1 / 3	University of Bristol: institution h-index 1,260 (OpenAlex)
Multicenter collaboration	0 / 3	OpenAlex lists 1 institution(s) in 1 country — scores zero (affiliation lists can be incomplete)
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 11160461)
Free to read	0 / 2	Behind a paywall — scores zero
Total	41 / 100	—

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