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Screening for deficits on intrinsic capacity domains and associated healthcare costs
Pagès A, Costa N, González-Bautista E, Mounié M, Juillard-Condat B, Molinier L, Cestac P, Rolland Y et al.. Archives of gerontology and geriatrics, 2022-02-07
Topic: Risk, prevention and care in population studies
Background/objective Intrinsic capacity (IC) defined by the World Health Organization is divided into six domains (locomotion, psychological, vitality/nutrition, cognition, vision and hearing). The main objective of this study therefore is to explore the association between healthcare costs and IC domains deficits among older patients. Participants and setting This longitudinal secondary analysis was performed on data from the Multidomain Alzheimer Preventive Trial (MAPT), a 3-year randomized controlled trial with non-demented community-dwelling participants aged 70 years or over. Methods We used an adapted version of the ICOPE (Integrated Care for Older People) Step 1 to screen for the six operational IC domains deficits at three time-points: baseline, one year and two years. We performed bivariate and multivariate analyzes using generalized linear models and generalized estimating equation models to identify associations between healthcare cost and deficits on IC domains. Results We analyzed 693 patients (aged 75.2 ± 4.22 years; 64% women (N = 442)). At baseline, among the included patients, 89% had at least one impairment in IC domains (N = 619). A deficit on visual capacity was associated with increased immediate healthcare costs (CR: 1.48; 95CI: [1.16-1.89]). Regarding persistent impairment of IC, locomotor (CR: 1.27; 95CI: [1.01-1.60], additional annual healthcare cost: €1092 per patient) and psychological (CR: 1.28; 95CI: [1.03-1.59], additional annual healthcare cost: €817 per patient) capacities were associated with increased healthcare costs. Conclusion In conclusion, this study showed that some deficits on IC domains, as measured by simple screening tests and questions, can be associated with higher healthcare costs. Clinicaltrials gov identifier: NCT00672685.
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APA 7th
Pagès, A., Costa, N., González-Bautista, E., Mounié, M., Juillard-Condat, B., Molinier, L., et al. (2022). Screening for deficits on intrinsic capacity domains and associated healthcare costs. Archives of gerontology and geriatrics. https://doi.org/10.1016/j.archger.2022.104654
Vancouver
Pagès A, Costa N, González-Bautista E, Mounié M, Juillard-Condat B, Molinier L, et al. Screening for deficits on intrinsic capacity domains and associated healthcare costs. Archives of gerontology and geriatrics. 2022. doi:10.1016/j.archger.2022.104654. PMID: 35193041.
BibTeX
@article{pages2022-35193041,
author = {Pagès, A. and Costa, N. and González-Bautista, E. and Mounié, M. and Juillard-Condat, B. and Molinier, L. and Cestac, P. and Rolland, Y. and others},
title = {{Screening for deficits on intrinsic capacity domains and associated healthcare costs}},
journal = {Archives of gerontology and geriatrics},
year = {2022},
doi = {10.1016/j.archger.2022.104654},
pmid = {35193041},
url = {https://doi.org/10.1016/j.archger.2022.104654}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
Key findings
- Results We analyzed 693 patients (aged 75.2 ± 4.22 years; 64% women (N = 442)).
- A deficit on visual capacity was associated with increased immediate healthcare costs (CR: 1.48; 95CI: [1.16-1.89]).
- Regarding persistent impairment of IC, locomotor (CR: 1.27; 95CI: [1.01-1.60], additional annual healthcare cost: €1092 per patient) and psychological (CR: 1.28; 95CI: [1.03-1.59], additional annual healthcare cost: €817 per patient) capacities were associated with increased healthcare costs.
- Conclusion In conclusion, this study showed that some deficits on IC domains, as measured by simple screening tests and questions, can be associated with higher healthcare costs.
Why it matters
This study found that certain deficits in intrinsic capacity domains, such as vision, locomotion and psychological capacity, were associated with higher healthcare costs in older adults. It is about healthcare costs and screening, not about treating, curing or preventing Alzheimer disease.
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Study details
- Study designrandomized controlled trial
- Participants442
- Evidence strengthHigh
How this study scored 62/100
Published in a peer-reviewed journal, and it is a randomised controlled trial. Scored zero for effect reported because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Archives of gerontology and geriatrics) |
| Journal's citation record | 1 / 4 | Archives of Gerontology and Geriatrics: journal h-index 132 (OpenAlex, 2026-10-29) |
| Study design | 11 / 12 | A randomised controlled trial |
| Strength of evidence | 5 / 5 | Rated “high” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 3 / 5 | 2022 — within 6 year(s) of the newest study here |
| Sample size | 2 / 4 | 442 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 1 / 2 | Randomised (as stated in the record) |
| Times cited | 3 / 7 | Cited 35 times (OpenAlex, 2026-10-10) |
| Citations per year | 2 / 5 | 5.8 citations a year over 6 year(s) since 2022 |
| Impact for its field and year | 3 / 6 | Cited 3.8× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 2 / 4 | Cited 23 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Philipe de Souto Barreto: h-index 51 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | Inserm: institution h-index 1,988 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 6 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 35193041) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 62 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1016/j.archger.2022.104654
- PubMed: 35193041
- Original source →
- Free full text: sciencedirect.com →
Full text: free to read — Unpaywall lists this copy as free to read: the link above (checked 10 Oct 2026).
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