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Modifiable risk factors for early- and late-onset dementia using the Korean national health insurance service database
Dougho Park, Myeonghwan Bang, Hyoung Seop Kim, Jong Hun Kim. The Journal of Prevention of Alzheimer s Disease, 2025-01-14
Topic: Risk, prevention and care in population studies
Higher socioeconomic status and increased frequency of physical activity were associated with a lower risk of both EOD and LOD. Rural residence, heavy alcohol consumption, and higher fasting blood sugar levels were associated with an increased risk of LOD, although there was no significant association with EOD. Overall, these factors impacted LOD more strongly than EOD. Demographic and lifestyle factors had a greater effect on LOD than blood pressure and relevant laboratory findings. Modifiable risk factors were associated with LOD and EOD. The influence of some modifiable risk factors was more pronounced in the LOD group than in the EOD group. Identifying modifiable risk factors associated with dementia can aid in the development of preventive strategies, underscoring the clinical importance of our findings.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Park, D., Bang, M., Kim, H. S., & Kim, J. H. (2025). Modifiable risk factors for early- and late-onset dementia using the Korean national health insurance service database. The Journal of Prevention of Alzheimer s Disease. https://doi.org/10.1016/j.tjpad.2024.100032
Vancouver
Park D, Bang M, Kim HS, Kim JH. Modifiable risk factors for early- and late-onset dementia using the Korean national health insurance service database. The Journal of Prevention of Alzheimer s Disease. 2025. doi:10.1016/j.tjpad.2024.100032. PMID: 39814657.
BibTeX
@article{park2025-39814657,
author = {Park, Dougho and Bang, Myeonghwan and Kim, Hyoung Seop and Kim, Jong Hun},
title = {{Modifiable risk factors for early- and late-onset dementia using the Korean national health insurance service database}},
journal = {The Journal of Prevention of Alzheimer s Disease},
year = {2025},
doi = {10.1016/j.tjpad.2024.100032},
pmid = {39814657},
url = {https://doi.org/10.1016/j.tjpad.2024.100032}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
Key findings
- Higher socioeconomic status and increased frequency of physical activity were associated with a lower risk of both EOD and LOD.
- Rural residence, heavy alcohol consumption, and higher fasting blood sugar levels were associated with an increased risk of LOD, although there was no significant association with EOD.
- Overall, these factors impacted LOD more strongly than EOD.
- Demographic and lifestyle factors had a greater effect on LOD than blood pressure and relevant laboratory findings.
- Modifiable risk factors were associated with LOD and EOD.
Why it matters
This case-control study using Korean national health insurance data found that higher socioeconomic status and more frequent physical activity were associated with lower risk of both early- and late-onset dementia. Rural residence, heavy alcohol consumption, and higher fasting blood sugar levels were associated with increased risk of late-onset dementia but not early-onset dementia, and overall these factors impacted late-onset dementia more strongly.
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Study details
- Study designcase-control study
- Evidence strengthModerate
How this study scored 42/100
Published in a peer-reviewed journal, and it is a case-control study. Scored zero for sample size, effect reported, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (The Journal of Prevention of Alzheimer s Disease) |
| Journal's citation record | 0 / 4 | The Journal of Prevention of Alzheimer s Disease: journal h-index 63 (OpenAlex, 2026-10-29) |
| Study design | 6 / 12 | A case-control study |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 1 / 7 | Cited 4 times (OpenAlex, 2026-10-10) |
| Citations per year | 1 / 5 | 1.3 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 2 / 6 | Cited 2.5× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 1 / 4 | Cited 4 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Jong Hun Kim: h-index 24 (OpenAlex, whole career) |
| Institution's track record | 0 / 3 | Pohang University of Science and Technology: institution h-index 595 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 39814657) |
| Free to read | 2 / 2 | Free to read |
| Total | 42 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1016/j.tjpad.2024.100032
- PubMed: 39814657
- Original source →
- Free full text: The Journal of Prevention of Alzheimer s Disease →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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