Home › Research › Getting a diagnosis
Mayo Normative Studies: Regression-based normative data for remote self-administration of the Stricker Learning Span, Symbols Test, and Mayo Test Drive Screening Battery Composite and validation in individuals with mild cognitive impairment and dementia
Nikki H. Stricker, Ryan D. Frank, Elizabeth Anne Boots, Winnie Z. Fan, Teresa J. H. Christianson, Walter K. Kremers, John L. Stricker, Mary M. Machulda et al.. The Clinical Neuropsychologist, 2025-03-11
Topic: Risk, prevention and care in population studies
No model terms met the a priori cut-off beyond the base model, including device type, response input source (e.g. mouse, etc.), or session interference. Norms showed expected low performance rates in CU and greater rates of low performance in MCI and dementia in independent validation samples. Typical normative models appear appropriate for remote self-administered MTD measures and are sensitive to cognitive impairment. Device type and response input source did not explain enough variance for inclusion in normative models but are important for individual-level interpretation. Future work will increase the inclusion of individuals from under-represented groups.
Key findings
- No model terms met the a priori cut-off beyond the base model, including device type, response input source (e.g. mouse, etc.), or session interference.
- Norms showed expected low performance rates in CU and greater rates of low performance in MCI and dementia in independent validation samples.
- Typical normative models appear appropriate for remote self-administered MTD measures and are sensitive to cognitive impairment.
- Device type and response input source did not explain enough variance for inclusion in normative models but are important for individual-level interpretation.
- Future work will increase the inclusion of individuals from under-represented groups.
Why it matters
This study provides normative data for remote self-administered cognitive tests and found these measures were sensitive to cognitive impairment in validation samples. Device type and response input source did not explain enough variance to be included in the models, though they remain important for interpreting individual scores.
New to this subject? Start with our plain-English guide: Getting a diagnosis →
Study details
- Participants167
- Effect size14.7%
- Evidence strengthLow
How this study scored 50/100
Published in a peer-reviewed journal. Scored zero for study design and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (The Clinical Neuropsychologist) |
| Journal's citation record | 1 / 4 | The Clinical Neuropsychologist: journal h-index 128 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 2 / 4 | 167 participants |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 2 / 7 | Cited 9 times (OpenAlex, 2026-10-10) |
| Citations per year | 2 / 5 | 3.0 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 3 / 6 | Cited 5.7× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 1 / 6 | Cited by 1 other studies in this library |
| Still being cited | 1 / 4 | Cited 9 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 4 / 4 | Last-listed author Ronald Carl Petersen: h-index 209 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | Washington University in St. Louis: institution h-index 1,962 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 3 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 40069913) |
| Free to read | 2 / 2 | Free to read |
| Total | 50 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1080/13854046.2025.2469340
- PubMed: 40069913
- Original source →
- Free full text: The Clinical Neuropsychologist →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Stricker, N. H., Frank, R. D., Boots, E. A., Fan, W. Z., Christianson, T. J. H., Kremers, W. K., et al. (2025). Mayo Normative Studies: Regression-based normative data for remote self-administration of the Stricker Learning Span, Symbols Test, and Mayo Test Drive Screening Battery Composite and validation in individuals with mild cognitive impairment and dementia. The Clinical Neuropsychologist. https://doi.org/10.1080/13854046.2025.2469340
Vancouver
Stricker NH, Frank RD, Boots EA, Fan WZ, Christianson TJH, Kremers WK, et al. Mayo Normative Studies: Regression-based normative data for remote self-administration of the Stricker Learning Span, Symbols Test, and Mayo Test Drive Screening Battery Composite and validation in individuals with mild cognitive impairment and dementia. The Clinical Neuropsychologist. 2025. doi:10.1080/13854046.2025.2469340. PMID: 40069913.
BibTeX
@article{stricker2025-40069913,
author = {Stricker, Nikki H. and Frank, Ryan D. and Boots, Elizabeth Anne and Fan, Winnie Z. and Christianson, Teresa J. H. and Kremers, Walter K. and Stricker, John L. and Machulda, Mary M. and others},
title = {{Mayo Normative Studies: Regression-based normative data for remote self-administration of the Stricker Learning Span, Symbols Test, and Mayo Test Drive Screening Battery Composite and validation in individuals with mild cognitive impairment and dementia}},
journal = {The Clinical Neuropsychologist},
year = {2025},
doi = {10.1080/13854046.2025.2469340},
pmid = {40069913},
url = {https://doi.org/10.1080/13854046.2025.2469340}
}
Studies this one cites
Referenced by this study and also in the alzhub library, so you can read them here.
Later studies that cite this one
1 study in the alzhub library lists this one in its references.
Related studies in Getting a diagnosis
Also tagged “assessment”
840 studies in the library carry the topic tag “assessment”; these are this study's neighbours in a fixed, alphabetical-by-hash tour of them, not the closest in content. All 840 tagged studies.