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Healthy dietary patterns in relation to cognitive performance and Alzheimer's disease mortality
Yiying Gong, Hui Chen, Yuxuan Gu, Jie Shen, Ting Shen, Yihong Ding, Mengxi Lu, Liyan Huang et al.. The journal of prevention of Alzheimer's disease, 2025-03-06
Topic: Brain imaging, connectivity and assessment
A total of 260 AD deaths occurred during a median follow-up of 9.8 years. Higher aMED score was associated with a lower risk of AD mortality (HRT3vs T1: 0.72, 95 % CI, 0.52-1.00, p-trend = 0.041). In a sub-sample of 2,713 participants in NHANES 2011-2014, 432 individuals had prevalent psychometric mild cognitive impairment (p-MCI). Higher aMED, MIND, HEI-2015, and hPDI were associated with lower odds of p-MCI. The potential contributors to these associations included higher intake levels of vegetables and nuts, moderate alcohol consumption, and lower intake level of sweets. The Mediterranean dietary pattern was associated with more favorable cognitive outcomes among middle-aged and older adults, underscoring the importance of a healthy diet for long-term benefits in cognitive and brain health.
Key findings
- A total of 260 AD deaths occurred during a median follow-up of 9.8 years.
- Higher aMED score was associated with a lower risk of AD mortality (HRT3vs T1: 0.72, 95 % CI, 0.52-1.00, p-trend = 0.041).
- In a sub-sample of 2,713 participants in NHANES 2011-2014, 432 individuals had prevalent psychometric mild cognitive impairment (p-MCI).
- Higher aMED, MIND, HEI-2015, and hPDI were associated with lower odds of p-MCI.
- The potential contributors to these associations included higher intake levels of vegetables and nuts, moderate alcohol consumption, and lower intake level of sweets.
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Study details
- Participants27,773
- Evidence strengthLow
How this study scored 55/100
Published in a peer-reviewed journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multi-centre collaboration and free to read, so those were left out: it earned 31 of the 56 points we could judge it on, which is 55 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (The journal of prevention of Alzheimer's disease) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 4 / 4 | 27,773 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 40055039) |
| Free to read | — / 2 | Access not recorded — left out of this score |
| Points | 31 / 56 | Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 31 of the 56 points we could judge it on is 55 out of 100. |
| Total | 55 / 100 | — |
What each of these 20 components measures, and what this score is not →
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Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Gong, Y., Chen, H., Gu, Y., Shen, J., Shen, T., Ding, Y., et al. (2025). Healthy dietary patterns in relation to cognitive performance and Alzheimer's disease mortality. The journal of prevention of Alzheimer's disease. https://doi.org/10.1016/j.tjpad.2025.100100
Vancouver
Gong Y, Chen H, Gu Y, Shen J, Shen T, Ding Y, et al. Healthy dietary patterns in relation to cognitive performance and Alzheimer's disease mortality. The journal of prevention of Alzheimer's disease. 2025. doi:10.1016/j.tjpad.2025.100100. PMID: 40055039.
BibTeX
@article{gong2025-40055039,
author = {Gong, Yiying and Chen, Hui and Gu, Yuxuan and Shen, Jie and Shen, Ting and Ding, Yihong and Lu, Mengxi and Huang, Liyan and others},
title = {{Healthy dietary patterns in relation to cognitive performance and Alzheimer's disease mortality}},
journal = {The journal of prevention of Alzheimer's disease},
year = {2025},
doi = {10.1016/j.tjpad.2025.100100},
pmid = {40055039},
url = {https://doi.org/10.1016/j.tjpad.2025.100100}
}
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