[Biochemical alterations in patients with Down syndrome]

Topic: Brain proteins, microglia and lab models

Results Plasma homocysteine value proved to be lower in 7 of the 30 and higher in 6 of the 30 patients studied than the reference range. No statistically significant correlation between the antioxidant activity and N-acetyl-beta-D-glucosaminidase values could be observed. There was no significant alteration in antioxidant activity level.

@article{varga2008-18565815,
  author  = {Varga, P. and V Oláh, A. and Oláh, E.},
  title   = {{[Biochemical alterations in patients with Down syndrome]}},
  journal = {Orvosi hetilap},
  year    = {2008},
  doi     = {10.1556/oh.2008.28327},
  pmid    = {18565815},
  url     = {https://doi.org/10.1556/oh.2008.28327}
}

Key findings

• Results Plasma homocysteine value proved to be lower in 7 of the 30 and higher in 6 of the 30 patients studied than the reference range.
• No statistically significant correlation between the antioxidant activity and N-acetyl-beta-D-glucosaminidase values could be observed.
• There was no significant alteration in antioxidant activity level.

Why it matters

In 30 patients with Down syndrome, plasma homocysteine was lower than the reference range in 7 and higher in 6, and there was no significant alteration in antioxidant activity level. No statistically significant correlation was found between antioxidant activity and N-acetyl-beta-D-glucosaminidase values.

Study details

• Participants30
• Evidence strengthLow

Read the original

• DOI: 10.1556/oh.2008.28327
• PubMed: 18565815
• Original source →
• Free full text: University of Debrecen Electronic Archive (University of Debrecen) →

Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).

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