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Delirium is independently associated with poor functional recovery after hip fracture
Marcantonio ER, Flacker JM, Michaels M, Resnick NM.. Journal of the American Geriatrics Society, 2000-06-01
Topic: Risk, prevention and care in population studies
Results Delirium occurred in 52/126 (41%) of patients, and persisted in 20/52 (39%) at hospital discharge, 15/52 (32%) at 1 month, and 3/52 (6%) at 6 months. However, after adjusting for these factors, delirium was still significantly associated with outcomes indicative of poor functional recovery 1 month after hip fracture: ADL decline (odds ratio (OR) = 2.6; 95% confidence interval (95% CI), 1.1- 6.1), decline in ambulation (OR = 2.6; 95% CI, 1.03-6.5), and death or new nursing home placement (OR = 3.0; 95% CI, 1.1-8.4). Conclusions Delirium is common, persistent, and independently associated with poor functional recovery 1 month after hip fracture even after adjusting for prefracture frailty.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Marcantonio, E. R., Flacker, J. M., Michaels, M., & Resnick, N. M. (2000). Delirium is independently associated with poor functional recovery after hip fracture. Journal of the American Geriatrics Society. https://doi.org/10.1111/j.1532-5415.2000.tb04718.x
Vancouver
Marcantonio ER, Flacker JM, Michaels M, Resnick NM. Delirium is independently associated with poor functional recovery after hip fracture. Journal of the American Geriatrics Society. 2000. doi:10.1111/j.1532-5415.2000.tb04718.x. PMID: 10855596.
BibTeX
@article{marcantonio2000-10855596,
author = {Marcantonio, E. R. and Flacker, J. M. and Michaels, M. and Resnick, N. M.},
title = {{Delirium is independently associated with poor functional recovery after hip fracture}},
journal = {Journal of the American Geriatrics Society},
year = {2000},
doi = {10.1111/j.1532-5415.2000.tb04718.x},
pmid = {10855596},
url = {https://doi.org/10.1111/j.1532-5415.2000.tb04718.x}
}
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Key findings
- Results Delirium occurred in 52/126 (41%) of patients, and persisted in 20/52 (39%) at hospital discharge, 15/52 (32%) at 1 month, and 3/52 (6%) at 6 months.
- However, after adjusting for these factors, delirium was still significantly associated with outcomes indicative of poor functional recovery 1 month after hip fracture: ADL decline (odds ratio (OR) = 2.6; 95% confidence interval (95% CI), 1.1- 6.1), decline in ambulation (OR = 2.6; 95% CI, 1.03-6.5), and death or new nursing home placement (OR = 3.0; 95% CI, 1.1-8.4).
- Conclusions Delirium is common, persistent, and independently associated with poor functional recovery 1 month after hip fracture even after adjusting for prefracture frailty.
Why it matters
In this cohort of hip fracture patients, delirium was common and often persisted, and it was linked to worse functional recovery one month later even after accounting for prefracture frailty. This concerns recovery after a fracture, not the treatment, cure or prevention of Alzheimer's disease.
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Study details
- Study designcohort study
- Effect sizeOR = 2.6; OR = 3.0
- Evidence strengthModerate
How this study scored 63/100
Published in a peer-reviewed journal, and it is a cohort study following people over time. Scored zero for sample size, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Journal of the American Geriatrics Society) |
| Journal's citation record | 3 / 4 | Journal of the American Geriatrics Society: journal h-index 344 (OpenAlex, 2026-10-29) |
| Study design | 7 / 12 | A cohort study following people over time |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2000 — older than 20 years, still counted |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 3 / 3 | Effect reported with a statistic (interval, p-value, ratio or similar) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 6 / 7 | Cited 684 times (OpenAlex, 2026-10-10) |
| Citations per year | 4 / 5 | 24.4 citations a year over 28 year(s) since 2000 |
| Impact for its field and year | 4 / 6 | Cited 12.3× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 3 / 6 | Cited by 14 other studies in this library |
| Still being cited | 2 / 4 | Cited 39 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Neil M. Resnick: h-index 62 (OpenAlex, whole career) |
| Institution's track record | 3 / 3 | Harvard University: institution h-index 3,235 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 4 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 10855596) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 63 / 100 | — |
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