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Cognitive impairment improves the predictive validity of the phenotype of frailty for adverse health outcomes: the three-city study
Avila-Funes JA, Amieva H, Barberger-Gateau P, Le Goff M, Raoux N, Ritchie K, Carrière I, Tavernier B et al.. Journal of the American Geriatrics Society, 2009-02-22
Topic: Risk, prevention and care in population studies
Objectives To determine whether adding cognitive impairment to frailty improves its predictive validity for adverse health outcomes. Participants Six thousand thirty community-dwelling persons aged 65 to 95. Measurements Frailty was defined as having at least three of the following criteria: weight loss, weakness, exhaustion, slowness, and low physical activity.
Key findings
- Participants Six thousand thirty community-dwelling persons aged 65 to 95.
- Measurements Frailty was defined as having at least three of the following criteria: weight loss, weakness, exhaustion, slowness, and low physical activity.
- Subjects meeting one or two criteria were prefrail and those meeting none as nonfrail.
- The lowest quartile in the Mini-Mental State Examination (MMSE) and the Isaacs Set Test (IST) was used to identify subjects with cognitive impairment.
Why it matters
This study examined whether adding cognitive impairment to a frailty definition improves prediction of adverse health outcomes in community-dwelling older persons. It concerns risk prediction, not treating, curing, or preventing Alzheimer's disease.
Study details
- Study designlongitudinal study
- Evidence strengthModerate
How this study scored 58/100
Published in a peer-reviewed journal, and it is a longitudinal study following the same people over time. Scored zero for sample size, effect reported, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Journal of the American Geriatrics Society) |
| Journal's citation record | 3 / 4 | Journal of the American Geriatrics Society: journal h-index 344 (OpenAlex, 2026-10-29) |
| Study design | 7 / 12 | A longitudinal study following the same people over time |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2009 — within 20 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 6 / 7 | Cited 519 times (OpenAlex, 2026-10-10) |
| Citations per year | 4 / 5 | 27.3 citations a year over 19 year(s) since 2009 |
| Impact for its field and year | 4 / 6 | Cited 16.0× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 2 / 6 | Cited by 6 other studies in this library |
| Still being cited | 2 / 4 | Cited 43 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 3 / 4 | Last-listed author Jean‐François Dartigues: h-index 87 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | Inserm: institution h-index 1,988 (OpenAlex) |
| Multi-centre collaboration | 2 / 3 | OpenAlex lists 4 institution(s) in 2 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 19245415) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 58 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
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Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Avila-Funes, J. A., Amieva, H., Barberger-Gateau, P., Le Goff, M., Raoux, N., Ritchie, K., et al. (2009). Cognitive impairment improves the predictive validity of the phenotype of frailty for adverse health outcomes: the three-city study. Journal of the American Geriatrics Society. https://doi.org/10.1111/j.1532-5415.2008.02136.x
Vancouver
Avila-Funes JA, Amieva H, Barberger-Gateau P, Le Goff M, Raoux N, Ritchie K, et al. Cognitive impairment improves the predictive validity of the phenotype of frailty for adverse health outcomes: the three-city study. Journal of the American Geriatrics Society. 2009. doi:10.1111/j.1532-5415.2008.02136.x. PMID: 19245415.
BibTeX
@article{avilafunes2009-19245415,
author = {Avila-Funes, J. A. and Amieva, H. and Barberger-Gateau, P. and Le Goff, M. and Raoux, N. and Ritchie, K. and Carrière, I. and Tavernier, B. and others},
title = {{Cognitive impairment improves the predictive validity of the phenotype of frailty for adverse health outcomes: the three-city study}},
journal = {Journal of the American Geriatrics Society},
year = {2009},
doi = {10.1111/j.1532-5415.2008.02136.x},
pmid = {19245415},
url = {https://doi.org/10.1111/j.1532-5415.2008.02136.x}
}
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