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Brain Health PRO: Evaluating a Web‐Based Multidomain Intervention to Improve Dementia Literacy and Self‐Efficacy
Sylvie Belleville, Nicole D. Anderson, John R. Best, Paul W. H. Brewster, January Durant, Mohamed Abdelhafid Kadri, Andrew Lim, Jody‐Lynn Lupo et al.. Alzheimer s & Dementia, 2025-12-01
Topic: Risk, prevention and care in population studies
A covariate-adjusted linear mixed model for the intention-to-treat sample (N = 353; mean age = 69.7) revealed a significant positive change in dementia literacy at 6 months (standardized change = 0.246; p = 0.012) and a significant improvement in self-efficacy at 12 months (standardized change = 0.157; p = 0.008). However, no significant change was observed in attitudes toward dementia. Brain Health Pro offers a personalized and accessible approach that can increase individuals' knowledge about dementia risk while enhancing their general self-efficacy. These dimensions are critical determinants of health. Improving them may foster long-lasting lifestyle changes to support sustained cognitive health.
Key findings
- A covariate-adjusted linear mixed model for the intention-to-treat sample (N = 353; mean age = 69.7) revealed a significant positive change in dementia literacy at 6 months (standardized change = 0.246; p = 0.012) and a significant improvement in self-efficacy at 12 months (standardized change = 0.157; p = 0.008).
- However, no significant change was observed in attitudes toward dementia.
- Brain Health Pro offers a personalized and accessible approach that can increase individuals' knowledge about dementia risk while enhancing their general self-efficacy.
- These dimensions are critical determinants of health.
- Improving them may foster long-lasting lifestyle changes to support sustained cognitive health.
Why it matters
In this longitudinal study of 353 people, the web-based multidomain intervention Brain Health Pro produced a significant positive change in dementia literacy at 6 months and in self-efficacy at 12 months, but no significant change in attitudes toward dementia. The authors say improving these dimensions may foster long-lasting lifestyle changes to support sustained cognitive health, but the study did not measure cognitive decline or dementia outcomes.
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Study details
- Study designlongitudinal study
- Participants353
- Evidence strengthModerate
How this study scored 49/100
Published in a peer-reviewed journal, and it is a longitudinal study following the same people over time. Scored zero for effect reported and randomised / blinded because the record does not state it. We have no data on senior author's track record, so that was left out: it earned 47 of the 96 points we could judge it on, which is 49 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Alzheimer s & Dementia) |
| Journal's citation record | 2 / 4 | Alzheimer s & Dementia: journal h-index 228 (OpenAlex, 2026-10-29) |
| Study design | 7 / 12 | A longitudinal study following the same people over time |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 2 / 4 | 353 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 0 / 7 | Cited 0 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.0 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 0 / 6 | Cited 0.0× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 0 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | — / 4 | OpenAlex's profile for last-listed author CCNA‐CAN‐THUMBS UP Study Group holds only 4 work(s), too few to judge a track record — left out of this score |
| Institution's track record | 2 / 3 | University of California San Diego: institution h-index 1,852 (OpenAlex) |
| Multi-centre collaboration | 3 / 3 | OpenAlex lists 12 institution(s) in 2 countries |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 41433832) |
| Free to read | 2 / 2 | Free to read |
| Points | 47 / 96 | Scored on 19 of 20 parts. We have no data for the rest, so they are left out: 47 of the 96 points we could judge it on is 49 out of 100. |
| Total | 49 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1002/alz70860_103191
- PubMed: 41433832
- Original source →
- Free full text: Alzheimer s & Dementia →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record's author list ends in “et al.”, so not every author is named. Check the citation against the original before you use it.
APA 7th
Belleville, S., Anderson, N. D., Best, J. R., Brewster, P. W. H., Durant, J., Kadri, M. A., et al. (2025). Brain Health PRO: Evaluating a Web‐Based Multidomain Intervention to Improve Dementia Literacy and Self‐Efficacy. Alzheimer s & Dementia. https://doi.org/10.1002/alz70860_103191
Vancouver
Belleville S, Anderson ND, Best JR, Brewster PWH, Durant J, Kadri MA, et al. Brain Health PRO: Evaluating a Web‐Based Multidomain Intervention to Improve Dementia Literacy and Self‐Efficacy. Alzheimer s & Dementia. 2025. doi:10.1002/alz70860_103191. PMID: 41433832.
BibTeX
@article{belleville2025-41433832,
author = {Belleville, Sylvie and Anderson, Nicole D. and Best, John R. and Brewster, Paul W. H. and Durant, January and Kadri, Mohamed Abdelhafid and Lim, Andrew and Lupo, Jody‐Lynn and others},
title = {{Brain Health PRO: Evaluating a Web‐Based Multidomain Intervention to Improve Dementia Literacy and Self‐Efficacy}},
journal = {Alzheimer s \& Dementia},
year = {2025},
doi = {10.1002/alz70860_103191},
pmid = {41433832},
url = {https://doi.org/10.1002/alz70860_103191}
}