27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
The average age for patient was 78.13 ± 10.25 and for caregivers was 54.64 ± 13.22 years. 5 key findings →
Design: cross-sectional Participants: 108 Evidence: low
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Dementia significantly impacts cognitive, behavioral, and functional abilities, creating challenges for both individuals and caregivers. 1 key finding →
Evidence: low
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Six key themes emerged: (1) challenges in daily care; (2) strain from behavioral and sleep disruptions; (3) difficulties in seeking help; (4) personal sacrifices of caregivers; (5) emotional burdens associated with caregiving, including comorbidity concerns of PwD; (6) limited dementia knowledge and essential caregiving skills. 3 key findings →
Evidence: low
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People with dementia (PWD) are frequently exposed to polypharmacy and potentially inappropriate medication use, in which the risks of medication use outweigh the benefits or the medication is not aligned with treatment goals. 5 key findings →
Evidence: low
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The Shifting Expectations narrative indicated that PwD's needs shifted to co-constructed needs with their family as PwD's independence declined. 5 key findings →
Evidence: low
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With the rising number of dementia cases, supporting family caregivers to maintain their well-being is crucial. 4 key findings →
Evidence: low
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Website goals were: providing ACP information and facilitating ACP conversations. 5 key findings →
Participants: 17 Evidence: low
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BackgroundClinician communication at the time of a dementia diagnosis often inadequately addresses patient and caregiver needs. 5 key findings →
Participants: 21 Evidence: low
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Dementia’s escalating incidence, coupled with its economic burden, highlights the need for architectural designs and forms that benefit people living with dementia. 5 key findings →
Evidence: low
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Addressing disparities related to Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD) is a priority for policymakers, practitioners, and researchers. 5 key findings →
Evidence: low
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Although the ASPR and ASIR remained stable or decreased globally, they both greatly increased in East Asia (ASPR: EAPC = 0.43; 95% CI 0.35, 0.51; ASIR: EAPC = 0.40; 95% CI 0.33, 0.47). 5 key findings →
Evidence: low
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In 2021, the age-standardised rates for ADOD were 694.01 (95% uncertainty intervals [UIs]: 602.88 to 794.08) for prevalence, 119.76 (95% UI: 104.96 to 135.89) for incidence, and 481.70 (95% UI: 228.79 to 1,023.96) for disability-adjusted life years (DALYs). 5 key findings →
Evidence: moderate
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Shorter telomeres were linked to stress, poor sleep, inflammation, and cardiometabolic markers. 5 key findings →
Evidence: high
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Mild cognitive impairment (MCI) represents a heterogeneous state between normal aging and dementia, with varied transition pathways. 3 key findings →
Participants: 272 Evidence: low
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Blood-based biomarkers hold significant promise for the early detection and diagnosis of Alzheimer’s disease (AD) and other dementias. 5 key findings →
Evidence: low
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Targeted interventions, as enhanced training and improved support systems, are essential to address these disparities and better support GPs. 2 key findings →
Design: cross-sectional Participants: 789 Evidence: low
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There were 558 respondents from residential aged care, community/primary care and hospital settings across all Australian states and territories. 5 key findings →
Evidence: low
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• This analysis consists of 567 participants revealed that vitamin B12 deficiency, not folate or vitamin B1 deficiency was associated with hippocampal atrophy detected by MRI-VSRAD analysis. • Vitamin B12 deficiency was associated with hyperhomocysteinemia. • Clear correlations were observed between hippocampal atrophy and vitamin B12 value. 4 key findings →
Participants: 323 Evidence: low
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BackgroundDementia is recognized as one of the prevalent neurocognitive disorders among older adults in Saudi Arabia, yet research efforts on its prevalence remains limited and fragmented, making it difficult to gain a full understanding of its epidemiology. 1 key finding →
Evidence: moderate
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EDDA achieved an area under the receiver-operating characteristic curve (AUROC) of 0.85 in the test set and 0.93 in the validation set. 5 key findings →
Evidence: low
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Recent advances in dementia research have expanded our understanding of modifiable risk factors, with air pollution being a well-established contributor. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
= 1), and three caregivers. Five key themes were identified, including ease of use, wearability, usefulness, transparency, and behavioral intention. 5 key findings →
Evidence: moderate
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The Extra Trees model achieved up to 99% accuracy for personalized wristband data, while the multilayer perceptron model performed best in general models with 98% accuracy. 5 key findings →
Evidence: low
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The presented results suggest the suitability of ecological handwriting analysis for the all-around monitoring of MCI, from early screening to disease progression evaluation. 4 key findings →
Participants: 57 Evidence: low
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HEK293, Neuro2a and SH-SY5Y expressing increased levels of α-synuclein were treated with sonicated α-synuclein pre-formed fibrils, to model seeded aggregation. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →