27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Depressive and anxiety symptoms were more pronounced among caregivers with longer caregiving duration (p = 0.01; p = 0.001) and those living with the care recipient (p = 0.04; p = 0.02). 4 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
The study evaluated 1,457 PD patients (1,050 primary; 407 secondary) alongside 2,100 matched non-PD controls. 5 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
Our findings provide evidence that age-related changes in the gut microbiota, particularly reductions in Bifidobacterium , partially mediate cognitive decline in older adults. 5 key findings →
Design: cross-sectional Participants: 578 Evidence: low
Full summary, score breakdown and related studies → Original source
Vascular risk factors were associated with CSVD burden and progression, and WMH and PVS progression were further associated with cortical atrophy and cognitive decline, underscoring the interconnected contributions of vascular risk, CSVD, and neurodegeneration to cognitive aging and dementia risk. 5 key findings →
Design: cross-sectional Participants: 289 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Our results showed that caregiving burden was negatively associated with the sense of ability.. 3 key findings →
Design: cross-sectional Participants: 355 Evidence: low
Full summary, score breakdown and related studies → Original source
Family physicians' empathy levels were independently associated with general, supportive, and accepting attitudes toward people with dementia, but not with exclusionary attitudes. 5 key findings →
Design: cross-sectional Participants: 412 Evidence: low
Full summary, score breakdown and related studies → Original source
Data collection started on June 3, 2026, and is planned to close on June 30, 2026. 2 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
Polypharmacy and PIMs are highly prevalent in end-of-life elderly cancer patients. 3 key findings →
Design: cross-sectional Participants: 183 Evidence: low
Full summary, score breakdown and related studies → Original source
This nationwide study provides epidemiological data on dementia and MCI among adults aged ≥ 60 years across all 12 administrative regions of Morocco. 1 key finding →
Design: cross-sectional Participants: 1,662 Evidence: low
Full summary, score breakdown and related studies → Original source
This study reports the prevalence of CF among elderly hypertensive residents of a community in Inner Mongolia. 5 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
This study demonstrated MMSE scores can be systematically extracted and curated from the VA EHR. 3 key findings →
Design: cross-sectional Participants: 49,555 Evidence: moderate
Full summary, score breakdown and related studies → Original source
We found opposite effects of age on FMAR at both short and long time scales, respectively (ßAge=0.014, 95% C.I. [0.009,0.019] and ßAge=-0.015, 95% C.I. [-0.026,-0.005]), as well as differences between women and men at long time scales (ßSexMen=+0.028, 95% C.I. [0.012,0.044]). 5 key findings →
Design: cross-sectional Evidence: moderate
Full summary, score breakdown and related studies → Original source
Higher prevalence was observed in the ID group relative to the general population for epilepsy, young-onset ADRD, and their comorbidity. 5 key findings →
Design: cross-sectional Participants: 847,430 Evidence: low
Full summary, score breakdown and related studies → Original source
Sociodemographic and clinical variables routinely recorded in PC EHRs may contribute to dementia identification. 3 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
Dementia public stigma was associated with education, dementia knowledge, media exposure, chronic diseases, and contact experience with people living with dementia. 5 key findings →
Design: cross-sectional Participants: 3,055 Evidence: low
Full summary, score breakdown and related studies → Original source
Medication adherence in older adults was strongly influenced by cognitive impairment, gender, health literacy and cohabitation. 4 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
Our findings suggest that serum brain-derived p-tau 217 and SV2A are more specific diagnostic biomarkers for reflecting brain damage and may not be disturbed by peripheral damage for AD patients. 5 key findings →
Design: cross-sectional Participants: 1,198 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Functional–behavioral subtypes can be identified in hospitalized AD patients, supporting multidimensional risk stratification and individualized care planning. 2 key findings →
Design: cross-sectional Participants: 118 Evidence: low
Full summary, score breakdown and related studies → Original source
Nurses showed moderate knowledge and positive attitudes, with knowledge closely linked to attitudes. 3 key findings →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
Wearable devices may facilitate the measurement and treatment of specific BPSD, as well as reduce caregiver burden. 2 key findings →
Design: cross-sectional Participants: 20 Evidence: moderate
Full summary, score breakdown and related studies → Original source
We examined whether natural language processing and acoustic analysis of spoken biographical recall could identify lexical and temporal speech features associated with language and memory performance in TLE. 5 key findings →
Design: cross-sectional Evidence: moderate
Full summary, score breakdown and related studies → Original source
Amyloid-β deposition begins in the earliest preclinical stages of Alzheimer's disease, long before cognitive decline is detectable by standard clinical assessments, which are often limited by ceiling effects and create a need for non-invasive, scalable markers. 1 key finding →
Design: cross-sectional Evidence: low
Full summary, score breakdown and related studies → Original source
In cognitively unimpaired older adults, associations between sleep disturbances and psycho-affective symptoms differ according to Aβ status. 2 key findings →
Design: cross-sectional Participants: 131 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Dementia is a major global health challenge; however, current diagnostic approaches often rely on invasive or costly procedures. 3 key findings →
Design: cross-sectional Participants: 88 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Only the reliability half of that contrast is individually significant. 2 key findings →
Design: cross-sectional Evidence: moderate
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →