Participants with more FTUs were found to have a slower biological ageing process. 5 key findings →
Participants: 22,900 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Participants with more FTUs were found to have a slower biological ageing process. 5 key findings →
Participants: 22,900 Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Vaccination is increasingly acknowledged as an effective preventive measure not only against specific infections, but also for the prevention of cardiovascular disease in high-risk patients. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
A total of 260 AD deaths occurred during a median follow-up of 9.8 years. 5 key findings →
Participants: 27,773 Evidence: low
Full summary, score breakdown and related studies → Original source
Arterial stiffness is a growing epidemic associated with increased risk of cardiovascular events, dementia, and death. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Full text may need a subscription
With the aging of the population, the burden of Alzheimer's disease (AD) is rapidly expanding. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Vascular dementia is the second most common type of dementia. 2 key findings →
Evidence: low
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The global burden of ischaemic strokes is almost 4-fold greater than haemorrhagic strokes. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Dementia and gait impairments often coexist in older adults and patients with neurodegenerative disease. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Identification of modifiable risk factors provides a crucial approach to the prevention of dementia. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Caffeine stimulates central nervous system on a short term. 3 key findings →
Participants: 1,409 Evidence: low
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It is broadly acknowledged that the onset of dementia in Alzheimer's disease (AD) may be modifiable by the management of risk factors. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
As the number of elderly persons in our country increases, more attention is being given to geriatric healthcare needs and successful ageing is becoming an important topic in medical literature. 2 key findings →
Design: longitudinal study Evidence: moderate
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The incidence and prevalence of dementia are expected to increase several-fold in the coming decades. 3 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
Dietary habits and vascular risk factors promote both Alzheimer's disease and cognitive impairment caused by vascular factors 1-3 . 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Executive function was associated with falls and gait speed slowing in older adults. 4 key findings →
Evidence: low
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The association between moderate-severe chronic kidney disease and white matter hyperintensity volume highlights the growing importance of kidney disease as a possible determinant of cerebrovascular disease and/or as a marker of microangiopathy. 5 key findings →
Participants: 615 Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Since 1989, four Canadian Consensus Conferences on the Diagnosis and Treatment of Dementia (CCCDTD) have provided evidence-based dementia guidelines for Canadian clinicians and researchers. 1 key finding →
Evidence: low
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We review the epidemiologic data that led to the recommendation to use diastolic hypertension and proteinuria as diagnostic criteria, as their combined presence was associated with an increased risk of fetal death and the birth of small-for-gestational-age neonates. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
These findings support the view that chronic financial pressures associated with low income exert a weathering effect that results in premature aging. 4 key findings →
Design: longitudinal study Evidence: moderate
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Developing a single-domain assay to identify individuals at high risk of future events is a priority for multi-disease and mortality prevention. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
We investigated the prevalence of dementia and mild cognitive impairment (MCI) and the factors associate with risk of dementia from a representative nationwide sample of Korean elders. 8,199 randomly-sampled Koreans aged 65 years or older were invited to participate in the Phase I screening assessment using Mini-Mental State Examination by door-to-door home visit, and 6,141 subjects (response rate = 74.9%) responded. 2 key findings →
Participants: 6,141 Evidence: low
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Of 3424 articles on potentially modifiable risk factors for dementia, 1719 met our inclusion criteria; 60 were deemed to be of good or fair quality. 2 key findings →
Design: cohort study Evidence: moderate
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At the baseline evaluation, 256 (62%) of 414 subjects were designated normal; 109 (26%). 2 key findings →
Design: cohort study Participants: 414 Evidence: moderate
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The increasing number of older adults has seen a corresponding growth in those affected by neurovascular diseases, including stroke and dementia. 1 key finding →
Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
To provide better prevention and treatment, we need to understand the environmental and genetic risks of Alzheimer's disease (AD). 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →