27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Exposure to metals is ubiquitous and emission sources include gasoline, diesel, smoke from wildfires, contaminated soil, water and food, medical implants, waste recycling facilities, subway exposures, and occupational environments. 1 key finding →
Design: longitudinal study Evidence: moderate
Full summary, score breakdown and related studies → Original source
Green spaces generally showed an inverse association with EOD risk that was almost linear for AD and inverted U-shaped for non-AD. 5 key findings →
Design: case-control study Evidence: moderate
Full summary, score breakdown and related studies → Original source
The univariable regression models revealed a higher likelihood of dementia diagnosis in patients with dysphagia (odds ratio = 1.493, 95% confidence interval = 1.000-2.228). 5 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
In 2017, the Lancet Commission on Dementia Prevention, Intervention, and Care included air pollution in its list of potential risk factors for dementia; in 2018, the Lancet Commission on Pollution concluded that the evidence for a causal relationship between fine particulate matter (PM) and dementia is encouraging. 1 key finding →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
The risk of dementia and Alzheimer's disease in Latin America and the Caribbean (LAC) rises with increasing age and polluted air. 2 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
The association of pesticide exposure with Parkinson's disease suggests a causative role. 5 key findings →
Design: case-control study Evidence: moderate
Full summary, score breakdown and related studies → Original source
Long-term exposures to air pollution and traffic noise were positively associated with MCI, mainly with the amnestic subtype. 4 key findings →
Design: cross-sectional Participants: 309 Evidence: low
Full summary, score breakdown and related studies → Original source
Epidemiological evidence of an association between Alzheimer's disease (AD) and the most frequently studied occupational exposures--pesticides, solvents, electromagnetic fields (EMF), lead and aluminium--is inconsistent. 1 key finding →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
The built environment has direct and indirect effects on mental health. 1 key finding →
Design: longitudinal study Evidence: high
Full summary, score breakdown and related studies → Original source
At baseline, 99 participants (10.1%) had covert brain infarcts and 91 (9.3%) had extensive periventricular white matter hyperintensities (WMHs). 5 key findings →
Participants: 976 Evidence: low
Full summary, score breakdown and related studies → Original source
Ambient 2-year averaged exposure of PM2.5 was associated with changes of neuroinflammatory markers, that is, CSF sTREM2 (β = -0.116, p = 0.0002). 5 key findings →
Participants: 1,131 Evidence: low
Full summary, score breakdown and related studies → Original source
Among 218 participants with 469 AF episodes we observed higher odds of AF following higher 24-hour mean levels of PM10 and O3, reaching statistical significance for PM10 levels averaged over the previous 12-24-hours [OR 1.10 (95%CI 1.01-1.19) per IQR of PM10 (7.8 µg/m3)]. 3 key findings →
Participants: 218 Evidence: low
Full summary, score breakdown and related studies → Original source
In this study, 1 282 032 participants ranging from 19 to 452 735 were included in 30 articles published from 2010 to 2022. 5 key findings →
Participants: 32 Evidence: low
Full summary, score breakdown and related studies → Original source
Increases in ambient PM2.5 concentrations were not consistently associated with increased hospital admissions rates. 3 key findings →
Participants: 63,287 Evidence: low
Full summary, score breakdown and related studies → Original source
Among the air toxics, higher 1,3-butadiene levels we estimated a hazard ratio of 1.12 (95 % CI: 1.00, 1.25) for incident dementia/CIND per IQR increase in 1,3-butadiene exposures. 5 key findings →
Participants: 1,612 Evidence: low
Full summary, score breakdown and related studies → Original source
Alzheimer's disease and related dementias lack effective treatment or cures and are major public health challenges. 2 key findings →
Design: longitudinal study Evidence: moderate
Full summary, score breakdown and related studies → Original source
During the study period, there were 1175 DDE hospital admissions. 1 key finding →
Design: longitudinal study Evidence: moderate
Full summary, score breakdown and related studies → Original source
The associations of particulate matter (PM) pollution with the morbidity of overall and subtypes of mental disorders (MDs), as well as the corresponding morbidity burden, remain understudied, especially in developing countries. 5 key findings →
Participants: 10,947 Evidence: low
Full summary, score breakdown and related studies → Original source
A discussion with theoretical and possible future research directions is provided and it is clear that the need is not only of longitudinal population studies and of better knowledge of epigenetics markers but, especially, of environmental policy interventions based on the green economy. 3 key findings →
Design: longitudinal study Evidence: moderate
Full summary, score breakdown and related studies → Original source
Between 1961 and 1971, military herbicides were used by the United States and allied forces for military purposes. 3 key findings →
Participants: 111,726 Evidence: low
Full summary, score breakdown and related studies → Original source
The authors investigated the hypothesis that exposure to pesticides could be related to central nervous system disorders in a prospective cohort study of 1,507 French elderly (1992-1998). 1 key finding →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
The results of this large retrospective, population-based study indicate that exposure to NO2 and CO is associated with an increased risk of dementia in the Taiwanese population. 3 key findings →
Participants: 29,547 Evidence: low
Full summary, score breakdown and related studies → Original source
Temperature extremes and variability both associated with stroke incidence and severity, migraine headaches, hospitalization in patients with dementia, and multiple sclerosis exacerbations. 3 key findings →
Participants: 364 Evidence: low
Full summary, score breakdown and related studies → Original source
Over 13 years, 65 336 patients with FCMD were identified, with 2584 developing dementia and 10 664 dying. 4 key findings →
Participants: 149 Evidence: low
Full summary, score breakdown and related studies → Original source
We found a significant correlation of CSF α-syn level with PM2.5 in urban participants. 4 key findings →
Participants: 933 Evidence: low
Full summary, score breakdown and related studies → Original source
10 of the 237 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →