30,580 Alzheimer's and dementia studies in plain English, each scored out of 100.
Delirium is an important independent prognostic determinant of hospital outcomes including new nursing home placement, death or new nursing home placement, and functional decline-even after controlling for age, gender, dementia, illness severity, and functional status. 3 key findings →
Design: cohort study Participants: 727 Evidence: moderate
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We developed machine learning prediction models for post-operative delirium that performed better than chance and are comparable with traditional stepwise logistic regression. 1 key finding →
Design: cohort study Participants: 134 Evidence: moderate
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The heterogeneous patterns and severity of conditions produce distinctive cumulative effects for each individual.5 Multimorbidity is associated with many adverse consequences, including death, disability, institutionalization, greater use of healthcare resources, poorer quality of life, and higher rates of adverse effects of treatment or interventions.1 Comprehensive strategies for healthcare delivery that are not disease specific, as well as interventions that target geriatric syndromes common in older adults with multimorbidity, show promise for this population,5-9 although the best approaches to decision-making and clinical management of older adults with multimorbidity remain unclear. 5 key findings →
Design: systematic review Evidence: high
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Among 2556 patients (mean age 79 ± 9 years; 56% women), delirium occurred in 957 (37%). 5 key findings →
Design: cohort study Participants: 2,556 Evidence: moderate
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For the last 17 years, an increase of mortality for patients with hip fracture and a higher mortality rate in men than in women were observed. 5 key findings →
Design: cohort study Participants: 3,992 Evidence: moderate
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If recent mortality trends continue, 160,000 more people in England and Wales will need palliative care by 2040. 2 key findings →
Participants: 469,305 Evidence: low
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Two longitudinal studies with different populations demonstrated that loneliness was a risk factor for the development of the pain, depression, and fatigue symptom cluster over time. 4 key findings →
Design: longitudinal study Participants: 115 Evidence: moderate
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Fifty-one studies from 16 States of India were included as 56 datasets, which estimated the prevalence of depression among Indian elderly population as 34.4% (95% CI: 29.3-39.7). 1 key finding →
Design: systematic review Evidence: high
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Clinicians treating people with a hip fracture should be vigilant towards post-operative delirium if their patients are older, have pre-existing cognitive impairment and poorer overall general health. 4 key findings →
Participants: 6,704 Evidence: low
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Among elderly people hospitalization of a spouse is associated with an increased risk of death, and the effect of the illness of a spouse varies among diagnoses. 4 key findings →
Participants: 518,240 Evidence: low
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Chronic kidney disease (CKD) is associated with poor outcomes, perhaps due to a high burden of comorbidity. 3 key findings →
Design: cohort study Participants: 530,771 Evidence: moderate
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Complexity at multiple levels needs to be understood and overcome to develop effective treatments and preventions for cognitive decline and AD dementia. 1 key finding →
Design: cohort study Evidence: moderate
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Severe psoriasis is associated with an increased risk of death from a variety of causes, with cardiovascular death being the most common aetiology. 4 key findings →
Design: cohort study Participants: 3,603 Evidence: moderate
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UK care home residents are often poorly served by existing healthcare arrangements. 4 key findings →
Design: cohort study Participants: 323 Evidence: moderate
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Critical outcomes were rate of falls (number of falls per unit time) and number of fallers (risk of experiencing one or more falls). 5 key findings →
Participants: 104 Evidence: high
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In those aged 65 years or older, delirium was overall associated (all p<0·001, age and sex adjusted) with dementia ( adj OR 3·63 [95% CI 2·65–4·98]), pre-admission dependency (2·63 [2·02–3·43]), comorbidity burden (1·04 [1·02–1·05]), and frailty (moderate vs low risk 3·62 [2·70–4·85] and high vs low risk 11·85 [7·24–19·42]), with stronger associations in patients without comorbid dementia than in those with comorbid dementia. 4 key findings →
Design: longitudinal study Participants: 290 Evidence: moderate
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The global burden associated with physical inactivity is substantial. 5 key findings →
Evidence: low
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The prevalence of geriatric ACHD is substantial, although severe lesions remain uncommon. 1 key finding →
Design: cohort study Participants: 3,239 Evidence: moderate
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At the beginning of June 2020, there were nearly 7 million reported cases of coronavirus disease 2019 (COVID-19) worldwide and over 400,000 deaths in people with COVID-19. 1 key finding →
Design: cohort study Evidence: moderate
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Delirium is a frequent complication in older ICU patients and often persists beyond their ICU stay. 3 key findings →
Design: cohort study Participants: 45 Evidence: moderate
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Understanding the mental health consequences of child maltreatment at different life stages is important in accurately quantifying the burden of maltreatment. 4 key findings →
Design: cohort study Participants: 56,082 Evidence: moderate
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A total of 1780 major operations (representing 9 556 171 survey-weighted operations nationally) were identified from 1477 community-living participants; mean (SD) age was 79.5 (7.0) years, with 56% being female. 5 key findings →
Design: cohort study Participants: 1,780 Evidence: moderate
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From 1996 through 2008, 5.55% of hospitalized patients resided in a nursing home 6 months later compared with 0.54% of nonhospitalized control patients. 5 key findings →
Design: retrospective cohort Participants: 762,243 Evidence: moderate
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Over a maximum follow-up of 26 years, the median time to event was 1·2 years (IQR 0·2-3·3) in the delirium group and 1·3 years (0·3-3·6) in the control group. 5 key findings →
Design: cohort study Participants: 909 Evidence: moderate
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Out of 929 patients, 184 (20%) experienced POD. 5 key findings →
Design: cohort study Participants: 929 Evidence: moderate
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Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled.
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 30,580 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 30,580 records, built mostly from automated pulls of Europe PMC (64.7% of the library) and OpenAlex (16.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,037 records (3.4% of the library) are not peer-reviewed — 964 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →
Newest studies, as a dated timeline → Atom feed Where this research is being discussed: events