27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
The analytical sample comprised 1481 NCI (76.7% female) and 515 MCI (69.7% female) participants. 5 key findings →
Design: longitudinal study Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
This multimodal intervention program demonstrated no effectiveness in mitigating cognitive decline. 4 key findings →
Design: randomized controlled trial Evidence: high
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Non-modifiable (age, apolipoprotein E (APOE) ɛ4 genotype and sex) and modifiable risk factors (co-morbidities at baseline, such as hypertension and cardiovascular disease, BMI, and sleep duration) were analyzed with mixed-effects models, adjusted for age and sex, to predict longitudinal measurements of WMH, Aβ and tau. 5 key findings →
Design: longitudinal study Participants: 494 Evidence: moderate
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Population-based clinic-pathological studies have established that the most common pathological substrate of dementia in community-dwelling elderly people is mixed, especially Alzheimer's disease (AD) and cerebrovascular ischemic disease (CVID), rather than pure AD. 2 key findings →
Design: longitudinal study Evidence: moderate
Full summary, score breakdown and related studies → Original source
Increasing oily fish intake has been proposed as a strategy for Alzheimer's disease (AD) prevention, but evidence for long-term benefit remains limited. 2 key findings →
Design: cohort Participants: 2,012 Evidence: null result
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Relationship between alcohol drinking and incident dementia remained uncertain. 2 key findings →
Design: cohort Participants: 296,715 Evidence: early
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Deterioration of the hippocampus occurs in elderly individuals with and without dementia, yet individual variation exists in the degree and rate of hippocampal decay. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Alzheimer's disease (AD) is the most common type of dementia and typically manifests through a progressive loss of episodic memory and cognitive function, subsequently causing language and visuospatial skills deficiencies, which are often accompanied by behavioral disorders such as apathy, aggressiveness and depression. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
Building infrastructures for international collaborations is necessary for managing the worldwide public health problem of AD and dementia. 1 key finding →
Evidence: low
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The increase in life expectancy has resulted in a high occurrence of dementia and Alzheimer's disease (AD). 5 key findings →
Evidence: high
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There is increasing evidence that hypertension may contribute to the development of dementia. 1 key finding →
Participants: 2,015 Evidence: moderate
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Dementia, a major cause of disability and institutionalization in older people, poses a serious threat to public health and to the social and economic development of modern society. 2 key findings →
Evidence: high
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Physical activity and exercise can improve cognitive function and reduce the risk for dementia. 4 key findings →
Design: cross-sectional Evidence: low
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Of the 799 participants (mean [SD] age, 46.2 [11.6] years; 424 women [53.1%]) randomized, 641 completed the 12-month follow-up and were included in the intention-to-treat analysis: 341 (n = 4 mosques) in the intervention group and 300 (n = 4 mosques) in the control group. 5 key findings →
Participants: 799 Evidence: high
Full summary, score breakdown and related studies → Original source Free full text
Hearing aid use was associated with a modestly lower risk of probable dementia overall (Hazard Ratios, HR, 0.91), but the association was confined to participants reporting improvements in hearing (HR 0.86), with no apparent benefit among those reporting poor improvement in hearing (HR 0.98). 2 key findings →
Design: longitudinal study Participants: 61,089 Evidence: moderate
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Consensus was achieved on 28 statements. 1 key finding →
Evidence: low
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Social isolation and loneliness have emerged as significant and modifiable risk factors for dementia, especially in older adults. 2 key findings →
Design: meta-analysis Evidence: high
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Over 13.45 years, 992 all-cause dementia cases were recorded. 5 key findings →
Design: cohort study Participants: 118,963 Evidence: moderate
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Alzheimer's disease (AD) lesions are characterized by the presence of numerous inflammatory proteins.
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Olive oil (OO) is the most representative food of the traditional Mediterranean Diet (MedDiet). 3 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source
Hypertension is associated with impaired cognition, and when combined with MCI, it may lead to a poor prognosis. 1 key finding →
Evidence: high
Full summary, score breakdown and related studies → Original source
In the US Medicare programme more than 75 000 percutaneous endoscopic gastrostomy tubes were placed during 1991, most of them in patients with head and neck cancer or neurogenic dysphagia due to dementia or stroke. 5 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source
These results may lead to a new avenue of inquiry in the prevention of Alzheimer's disease. 3 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
Racial disparities in dementia may be reduced by prevention and management of disease and promoting educational attainment among blacks and Hispanics. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source Free full text
The potential adverse effects of prophylactic bilateral oophorectomy on heart health, neurological health, bone health and quality of life should be carefully weighed against its potential benefits for cancer risk reduction in women at average risk of ovarian cancer. 3 key findings →
Design: cohort study Evidence: moderate
Full summary, score breakdown and related studies → Original source Free full text
10 of the 859 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →