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Research

31,380 Alzheimer's and dementia studies in plain English, each scored out of 100.

Find studies

Showing 126–150 of 424 studies in Getting a diagnosis · tagged Diagnosis (page 6 of 17) · 31,380 in the whole library · How the 0–100 score works

Download bibliography of these 424 studies, in this order: BibTeX (.bib) · RIS (.ris)

Browse by subject, author or institution

Each number is how many studies that link shows, with your other filters kept.

Other subjects

Authors

Names as each record prints them; the same person can appear under two spellings.

Institutions

From OpenAlex; 16,851 studies have no institution on record and are not counted here.

What “Getting a diagnosis” covers

Getting a diagnosis — How Alzheimer's is identified, how accurate the tests are, and how early it can be caught.

A note on reading research. One study is rarely the final word.

We try to note the size of a study, whether it was in humans or animals, and how early-stage the finding is. If a summary here doesn't make that clear, treat it with extra caution and check the original source.

Clinico-neuropathological correlation of Alzheimer's disease in a community-based case series

✓ Peer-reviewed alzhub usefulness score 57 out of 100. Journal of the American Geriatrics Society 1999-05-01

This study of a large series of community-based incident dementia cases provides a way of judging the adequacy of currently available clinical diagnostic criteria. 2 key findings →

Participants: 134 Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Language, literacy, and sensory impairments and missing cognitive test scores in the Harmonized Cognitive Assessment Protocol of the China Health and Retirement Longitudinal Study

✓ Peer-reviewed alzhub usefulness score 57 out of 100. Aging Clinical and Experimental Research 2025-05-12

We observed high levels of missing data in most cognitive test items - on average 13% and as high as 65%. 5 key findings →

Design: longitudinal study Participants: 9,755 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Discrepancies in assessing intellectual disability levels in adults with Down syndrome: Implications for dementia diagnosis

✓ Peer-reviewed alzhub usefulness score 57 out of 100. Alzheimer s & Dementia 2025-06-01

Inter-rater agreement for ID level classification was 95% within sites but 60% between sites. 5 key findings →

Design: cohort study Participants: 673 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): report of the NINDS-SPSP international workshop

✓ Peer-reviewed alzhub usefulness score 57 out of 100. Neurology 1996-07-01

To improve the specificity and sensitivity of the clinical diagnosis of progressive supranuclear palsy (PSP, Steele-Richardson-Olszewski syndrome), the National Institute of Neurological Disorders and Stroke (NINDS) and the Society for PSP, Inc. (SPSP) sponsored an international workshop to develop an accurate and universally accepted set of criteria for this disorder.

Full summary, score breakdown and related studies → Original source Full text may need a subscription

The neuropathological diagnosis of Alzheimer's disease

✓ Peer-reviewed alzhub usefulness score 56 out of 100. Molecular neurodegeneration 2019-08-02

Alzheimer's disease is a progressive neurodegenerative disease most often associated with memory deficits and cognitive decline, although less common clinical presentations are increasingly recognized. 2 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Six-item screener to identify cognitive impairment among potential subjects for clinical research

✓ Peer-reviewed alzhub usefulness score 56 out of 100. Medical care 2002-09-01

The six-item screener is a brief and reliable instrument for identifying subjects with cognitive impairment and its diagnostic properties are comparable to the full MMSE. 1 key finding →

Evidence: moderate

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease

✓ Peer-reviewed alzhub usefulness score 56 out of 100. Archives of neurology 2001-11-01

An international group of clinical and basic scientists participated in the Frontotemporal Dementia and Pick's Disease Criteria Conference at the National Institutes of Health in Bethesda, Md, on July 7, 2000, to reassess clinical and neuropathological criteria for the diagnosis of frontotemporal dementia (FTD). 4 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

The prevalence of dementia and Alzheimer's disease in Shanghai, China: impact of age, gender, and education

✓ Peer-reviewed alzhub usefulness score 56 out of 100. Annals of neurology 1990-04-01

We report the prevalence rates for dementia and Alzheimer's disease (AD) obtained from a probability sample survey of 5,055 noninstitutionalized older persons in Shanghai, China. 2 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

The diagnostic challenge of psychiatric symptoms in neurodegenerative disease: rates of and risk factors for prior psychiatric diagnosis in patients with early neurodegenerative disease

✓ Peer-reviewed alzhub usefulness score 56 out of 100. The Journal of clinical psychiatry 2011-02-01

Depression was the most common psychiatric diagnosis in all groups. 2 key findings →

Participants: 69 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Plasma Exosomal miRNAs in Persons with and without Alzheimer Disease: Altered Expression and Prospects for Biomarkers

✓ Peer-reviewed alzhub usefulness score 56 out of 100. PloS one 2015-10-01

To assess the value of exosomal miRNAs as biomarkers for Alzheimer disease (AD), the expression of microRNAs was measured in a plasma fraction enriched in exosomes by differential centrifugation, using Illumina deep sequencing. 4 key findings →

Participants: 35 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

The frontotemporal dementia-motor neuron disease continuum

✓ Peer-reviewed alzhub usefulness score 56 out of 100. Lancet (London, England) 2016-03-14

Early reports of cognitive and behavioural deficits in motor neuron disease might have been overlooked initially, but the concept of a frontotemporal dementia-motor neuron disease continuum has emerged during the past decade. 5 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Vitamin D deficiency is associated with low mood and worse cognitive performance in older adults

✓ Peer-reviewed alzhub usefulness score 56 out of 100. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2006-12-01

In a cross-section of older adults, vitamin D deficiency was associated with low mood and with impairment on two of four measures of cognitive performance. 4 key findings →

Design: cross-sectional Participants: 80 Evidence: moderate

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Eye‐Tracking‐Based Cognitive Assessment Predicts the Risk of Memory Decline: A Community‐Based Cohort Study

✓ Peer-reviewed alzhub usefulness score 56 out of 100. Geriatrics and gerontology international/Geriatrics & gerontology international 2026-03-01

Approximately half (54.5%, 35/55) of participants showed a decline in RBMT scores during the 2-year follow-up and were defined as the memory decline group. 4 key findings →

Design: longitudinal study Participants: 55 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Clinical practice guidelines on addressing cognitive impairment in treatable dementias

✓ Peer-reviewed alzhub usefulness score 56 out of 100. Indian Journal of Psychiatry 2025-01-01

This is because of the ambiguity surrounding the terminology used to characterize reversible dementia—the variation in the population being studied, or the existence of subclinical instances that are difficult to diagnose.[3] By and large however, the proportion of reversible dementias compared to the irreversible dementias is very low. 5 key findings →

Design: meta-analysis Evidence: high

Full summary, score breakdown and related studies → Original source Free full text

Contextualization of Harmonized Cognitive Assessment Protocol (HCAP) in an aging population in rural low‐resource settings in Africa: Experiences and strategies adopted to optimize effective adaption of cognitive tests in Kenya

✓ Peer-reviewed alzhub usefulness score 56 out of 100. Alzheimer s & Dementia 2025-08-01

The rural setting presented unique challenges including: low literacy rates (60.1% of participants had no schooling), diverse language use (primarily Giriama and Swahili), limited infrastructure (e.g., 44.8% of households had electricity), restrictive cultural norms that influenced data collection (e.g., in-home interviews were often conducted outdoors with destructions). 5 key findings →

Design: longitudinal study Participants: 202 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Speech‐based digital cognitive assessment for clinical trials: Detecting cognitive impairment stages and AD biomarker relations across European cohorts

✓ Peer-reviewed alzhub usefulness score 56 out of 100. Alzheimer s & Dementia 2026-05-01

SB-C significantly differentiated cognitively unimpaired and impaired groups (P < 0.001), correlated with standard cognitive measures, and showed moderate-to-high area under the curve (0.56-0.82) for classifying biomarker positivity, with strongest results in BioFINDER-Primary Care. 2 key findings →

Design: longitudinal study Participants: 736 Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop

✓ Peer-reviewed alzhub usefulness score 55 out of 100. Neurology 1996-11-01

We identified optimal staining methods for each of these and devised a protocol for the evaluation of cortical LB frequency based on a brain sampling procedure consistent with CERAD. 5 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

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Where “Free full text” comes from

Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read

How the 0–100 score works — and why some entries are capped

This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.

  • Journal tier up to 10 pts
  • Journal's citation record up to 4 pts
  • Study design up to 12 pts
  • Strength of evidence up to 5 pts
  • Peer-review validation up to 10 pts
  • How recent up to 5 pts
  • Sample size up to 4 pts
  • Effect reported up to 3 pts
  • Studied in people up to 3 pts
  • Randomized / blinded up to 2 pts
  • Times cited up to 7 pts
  • Citations per year up to 5 pts
  • Impact for its field and year up to 6 pts
  • Cited by studies here up to 6 pts
  • Still being cited up to 4 pts
  • Senior author's track record up to 4 pts
  • Institution's track record up to 3 pts
  • Multicenter collaboration up to 3 pts
  • Indexed in PubMed up to 2 pts
  • Free to read up to 2 pts

Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.

Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.

We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.

The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.

See the whole rubric drawn out → — four charts covering all 31,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.

What this library is — and isn't

This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 31,380 records, built mostly from automated pulls of Europe PMC (65.6% of the library) and OpenAlex (16.2%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.

1,048 records (3.3% of the library) are not peer-reviewed — 973 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.

See the full, machine-readable breakdown of this library's coverage →

Newest studies, as a dated timeline →    Atom feed    Where this research is being discussed: events