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white-matter
905 studies tagged white-matter, dated 1975-09-01 to 2026-09-14. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Pathway-specific polygenic risk scores reveal underlying mechanisms of cerebral small vessel disease 2026-09-14
- Cerebral Small Vessel Disease and Risk of Cardiovascular Events and All-Cause Mortality: The Framingham Heart Study 2026-09-07
- Regional Distribution of Mineralized Blood Vessels in Alzheimer Disease and Clinicopathological Associations: A Multicenter Autopsy Study 2026-09-01
Studies
905 studies carry this tag.
Date range
1975 to 2026
Top journals
- Neurology 93
- Stroke 61
- Alzheimer s & Dementia 31
- Brain : a journal of neurology 20
- Annals of neurology 19
342 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Phase-contrast magnetic resonance imaging (PC-MRI) is a noninvasive reliable technique, which enables quantification of cerebrospinal fluid (CSF) and total cerebral blood flows (tCBF).
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Chronic cerebral hypoperfusion has been associated with cognitive decline in aging and Alzheimer's disease.
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An inflammatory process in the central nervous system (CNS) is believed to play an important role in the pathway leading to neuronal cell death in a number of neurodegenerative diseases including Parkinson's disease, Alzheimer's disease, prion diseases, multiple sclerosis and HIV-dementia.
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43/100
In chronic liver failure, manganese accumulation is responsible for the pallidal MRI T1 hyperintensity.
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Thirty percent of the cases had significant cerebrovascular parenchymal pathology scores (CVDPS), 54% had significant AD pathology, and 18% had HS.
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Differences in white matter hyperintensities (WMH) associated with increasing cognitive impairment appear related to both extent and spatial location.
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41/100
White matter hyperintensities (WMH), commonly found on T2-weighted FLAIR brain MR images in the elderly, are associated with a number of neuropsychiatric disorders, including vascular dementia, Alzheimer's disease, and late-life depression.
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Type 2 diabetes is associated with cognitive dysfunction and increases the risk of dementia in the elderly.
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Stroke is an important risk factor for dementia, but the exact mechanisms involved in cognitive decline remain unclear.
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The development of common standards represents a first step in a process of use, validation and refinement.
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High white matter grade (WMG) on magnetic resonance imaging (MRI) is a risk factor for dementia, stroke and disability.
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Data on behavioral changes after thalamic lesion are sparse and largely based on isolated reports of patients with thalamic strokes.
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The complement system provides an innate defence mechanism against pathogenic microorganisms.
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50/100
The NBV significantly correlated with all clinical scores (Rankin, NIH Stroke Scale, Barthel, structured interview for the diagnosis of Alzheimer dementia and multi-infarct dementia, Mattis dementia rating scale) at both time points independently of age and sex.
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Cardiovascular and cerebrovascular disorders are the main cause of death and permanent disability worldwide.
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Depressive symptoms were associated with increased risk of MCI, and this association was independent of underlying vascular disease.
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Our findings show an association between low circulating levels of one of the most important components of the human antioxidant system and the presence of frailty.
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Quantitative magnetic resonance imaging and neuropsychological evaluations were performed in 1820 dementia- and stroke-free participants from the Framingham Offspring Cohort.
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Cerebral microbleeds might indicate a higher risk of future intracerebral hemorrhage and may be a marker of cerebral small-vessel disease and cerebral amyloid angiopathy.
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IL-6 levels were negatively associated with performance on the MMSE in this multiethnic cohort.
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The direct visualization of retinal vessels provides a unique opportunity to study cerebral small vessel disease, because these vessels share many features.
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The presence of either severe WMH or MTA was associated with a modest but non-significant increase in frequency of mild cognitive deficits (severe WMH: odds ratio (OR) = 1.9 (95% confidence interval (CI), 1.0 to 3.7); MTA present: OR = 1.5 (95% CI, 0.8 to 2.8)).
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We investigated whether the cerebrospinal fluid (CSF) biomarkers beta-amyloid 1-42 (Abeta1-42), total tau (t-tau) protein and tau protein phosphorylated at threonine 181 (p-tau181) could discriminate Alzheimer's disease (AD) from vascular dementia (VD) patients.
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The new MRI rating scale for WMH in cholinergic pathways is reliable and shows stronger correlations with cognitive performance than a general WMH rating scale in AD with WMH.
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We found WMH and lacunes to be independently associated with general cognitive function in a sample of independently living elderly.
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Inflammatory processes may be involved in the pathogenesis of cerebral small-vessel disease, in particular, the development of white matter lesions.
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A profile of equal impairment on tests of executive control and memory along with radiologic evidence involving about one-fourth of the cerebral white matter as measured by the Leukoaraiosis Scale may be sufficient for a diagnosis of subcortical vascular dementia.
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With increasing emphasis on early diagnosis of Alzheimer disease (AD), clinical research has focused on the identification of risk factors that may be modified at a preclinical and early clinical stage of dementing disorders.
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Cerebral small-vessel disease is common in older people and may contribute to the development of dementia.
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Cerebral blood flow (CBF) velocity is decreased in patients with Alzheimer's disease.
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Neuroinflammation has an established link with AIDS-related dementia but has not been investigated in the post-highly active anti-retroviral therapy (HAART) era.
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Evidence suggests that a high concentration of C-reactive protein (CRP) is a cardiovascular risk factor and an important correlate of cognitive disorders and depression.
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These cross-sectional data provide evidence that tHcy is a risk factor for white matter damage.
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Microglial cells represent the immune system of the mammalian brain and therefore are critically involved in various injuries and diseases.
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Subclinical structural brain abnormalities in high-functioning older adults can increase the risk of developing physical disabilities and declining in motor performance.
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Older adults with dementia who take atypical antipsychotics have a similar risk of ischaemic stroke to those taking typical antipsychotics.
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50/100
Blood pressure and indicators of small-vessel disease in the brain may be associated with atrophy of structures affected by Alzheimer pathology.
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Age-related white matter changes (ARWMC) on brain MRI have been associated with cognitive, motor, mood and urinary disturbances.
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The mechanisms underlying blood-brain barrier (BBB) compromise in human immunodeficiency virus (HIV) infection and the ways in which BBB compromise might impair neurocognitive function remain poorly understood.
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In contrast to observations in individuals not treated with CART, we found no relationship between CSF markers and neurological status in this CART-using cohort with advanced HIV/AIDS.
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Mid-life stroke risk factors have been related to late-life cognitive impairment.
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These findings support the hypothesis that the metabolic syndrome contributes to cognitive impairment in elders, but primarily in those with high level of inflammation.
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Vascular cognitive impairment (VCI) was proposed as an umbrella term to include subjects affected with any degree of cognitive impairment resulting from cerebrovascular disease (CVD), ranging from mild cognitive impairment (MCI) to vascular dementia.
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The MRC Cognitive Function and Ageing Study (CFAS) is a prospective longitudinal study of a population-based cohort of elderly people in six UK sites, evaluated using psychometric instruments and questionnaires to elucidate physical and mental health.
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Cerebral white matter lesions are frequently observed on magnetic resonance imaging (MRI) scans in elderly people and are associated with stroke and dementia.
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We review accumulating evidence that cerebrovascular amyloid deposition (cerebral amyloid angiopathy [CAA]) is an independent risk factor for cognitive dysfunction.
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A substantial proportion of stroke survivors have very poor HRQoL.
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Unesterified cholesterol is an essential structural component of the plasma membrane of every cell.
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The frontal lobes are most severely affected by SIVD.
From across this tag
9 of the 904 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.
- Effects of diabetes on microglial physiology: a systematic review of in vitro, preclinical and clinical studies
- Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease
- Diffusion kurtosis imaging (gen)omics unravels mechanisms of cerebral small vessel disease
- Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration
- Cerebrospinal fluid YKL‐40 relates to white matter hyperintensity progression in females but not males over a 6‐year period
- Pathogenesis of cerebral microbleeds: In vivo imaging of amyloid and subcortical ischemic small vessel disease in 226 individuals with cognitive impairment
- Neurons in the white matter of the adult human neocortex
- Sevoflurane and Isoflurane induce structural changes in brain vascular endothelial cells and increase blood-brain barrier permeability: Possible link to postoperative delirium and cognitive decline
- Hypoxic-ischemic brain lesions found in asphyxiating neonates