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Newest in this topic

  1. Pathway-specific polygenic risk scores reveal underlying mechanisms of cerebral small vessel disease 2026-09-14
  2. Cerebral Small Vessel Disease and Risk of Cardiovascular Events and All-Cause Mortality: The Framingham Heart Study 2026-09-07
  3. Regional Distribution of Mineralized Blood Vessels in Alzheimer Disease and Clinicopathological Associations: A Multicenter Autopsy Study 2026-09-01

Studies

903 studies carry this tag.

Date range

1975 to 2026

Top journals

  • Neurology 93
  • Stroke 61
  • Alzheimer s & Dementia 31
  • Brain : a journal of neurology 20
  • Annals of neurology 19

342 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Neurons in the white matter of the adult human neocortex

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Frontiers in neuroanatomy 2009-06-09 Brain scans and imaging

    The white matter (WM) of the adult human neocortex contains the so-called "interstitial neurons".

  2. Beta-amyloid, blood vessels, and brain function

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Stroke 2009-05-14 Brain tissue and pathology

    Cerebrovascular disease and Alzheimer disease are common diseases of aging and frequently coexist in the same brain.

  3. Silent ischemic infarcts are associated with hemorrhage burden in cerebral amyloid angiopathy

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Neurology 2009-04-01 Brain scans and imaging

    MRI evidence of small subacute infarcts is present in a substantial proportion of living patients with advanced cerebral amyloid angiopathy (CAA).

  4. Carotid artery atherosclerosis, MRI indices of brain ischemia, aging, and cognitive impairment: the Framingham study

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Stroke 2009-03-05 Hippocampus size on brain scans

    Carotid atherosclerosis markers were associated with MRI indices of brain ischemia and aging and with cognitive impairment in a community-based sample of middle-aged adults.

  5. Our data suggest that vascular abnormalities, independently of blood pressure levels, may play a role in the setting of subjective memory complaints as well as of WMH in elderly hypertensive patients.

  6. Microvasculature changes and cerebral amyloid angiopathy in Alzheimer's disease and their potential impact on therapy

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Acta neuropathologica 2009-02-22 Brain tissue and pathology

    The introduction of immunotherapy and its ultimate success will require re-evaluation of the pathogenesis of Alzheimer's disease particularly with regard to the role of the ageing microvasculature and the effects of APOE genotype.

  7. Cerebral microbleeds: a guide to detection and interpretation

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. The Lancet. Neurology 2009-02-01 How common it is

    Cerebral microbleeds (CMBs) are increasingly recognised neuroimaging findings in individuals with cerebrovascular disease and dementia, and in normal ageing.

  8. Regional white matter integrity differentiates between vascular dementia and Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. Stroke 2009-01-22 Brain scans and imaging

    FA reduction in forceps minor was the most significant area of difference between AD and VaD.

  9. Structural neuroimaging in Altheimer's disease: do white matter hyperintensities matter?

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Dialogues in clinical neuroscience 2009-01-01 Brain scans and imaging

    The targeted brain dysfunction that accompanies aging can have a devastating effect on cognitive and intellectual abilities.

  10. MRI biomarkers of vascular damage and atrophy predicting mortality in a memory clinic population

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Stroke 2008-12-24 Brain scans and imaging

    Simple MRI biomarkers, in addition to their diagnostic use, have a prognostic value with respect to mortality in a memory clinic population.

  11. Glyconanoparticles allow pre-symptomatic in vivo imaging of brain disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2008-12-23 Vascular contributions

    Initial recruitment of leukocytes in inflammation associated with diseases such as multiple sclerosis (MS), ischemic stroke, and HIV-related dementia, takes place across intact, but activated brain endothelium.

  12. Understanding white matter disease: imaging-pathological correlations in vascular cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Stroke 2008-12-08 Biomarkers

    Most strokes are covert and observed incidentally on brain scans, but their presence increases risk of overt stroke and dementia.

  13. Docosahexaenoic acid and the aging brain

    ✓ Peer-reviewed alzhub usefulness score 42 out of 100. The Journal of nutrition 2008-12-01 Risk genes beyond APOE

    The dietary essential PUFA docosahexaenoic acid [DHA; 22:6(n-3)] is a critical contributor to cell structure and function in the nervous system, and deficits in DHA abundance are associated with cognitive decline during aging and in neurodegenerative disease.

  14. Presence of electroencephalogram burst suppression in sedated, critically ill patients is associated with increased mortality

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Critical care medicine 2008-12-01 Clinical safety

    The presence of burst suppression, which was unexpectedly high in this medical intensive care unit population, was an independent predictor of increased risk of death at 6 months.

  15. Cerebral white matter: neuroanatomy, clinical neurology, and neurobehavioral correlates

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Annals of the New York Academy of Sciences 2008-10-01 Getting a diagnosis

    Lesions of the cerebral white matter (WM) result in focal neurobehavioral syndromes, neuropsychiatric phenomena, and dementia.

  16. Periventricular white matter hyperintensities increase the likelihood of progression from amnestic mild cognitive impairment to dementia

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Journal of neurology 2008-09-25 Brain scans and imaging

    55 of the 152 (36.2 %) aMCI subjects progressed to AD.

  17. Immobility-related complications are very common in the first year after a severely disabling stroke.

  18. MRI correlates of neurofibrillary tangle pathology at autopsy: a voxel-based morphometry study

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Neurology 2008-09-01 Brain scans and imaging

    Patterns of gray matter loss are associated with neurofibrillary tangle (NFT) pathology, specifically with NFT burden at Braak stages III and IV and with Braak stage itself at higher stages.

  19. Exposure to antipsychotics and risk of stroke: self controlled case series study

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. BMJ (Clinical research ed.) 2008-08-28 Vascular contributions

    All antipsychotics are associated with an increased risk of stroke, and the risk might be higher in patients receiving atypical antipsychotics than those receiving typical antipsychotics.

  20. Do in vivo experimental models reflect human cerebral small vessel disease? A systematic review

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008-08-13 Vascular contributions

    Cerebral small vessel disease (SVD) is a major cause of stroke and dementia.

  21. Brain morphology in older African Americans, Caribbean Hispanics, and whites from northern Manhattan

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Archives of neurology 2008-08-01 Caregiving

    Older age and vascular disease, particularly among African Americans, are associated with increased brain atrophy and WMH burden.

  22. Atrial fibrillation in stroke-free patients is associated with memory impairment and hippocampal atrophy

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. European heart journal 2008-07-29 Risk factors

    AF contributes to stroke and secondary cognitive decline.

  23. Sulcal morphology changes and their relationship with cortical thickness and gyral white matter volume in mild cognitive impairment and Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. NeuroImage 2008-07-22 Mild cognitive impairment

    We investigated the changes of sulcal shape (average mean curvature in folded regions and sulcal depth) in mild cognitive impairment (MCI) and Alzheimer's disease (AD) using quantitative surface-based methods in a large sample of magnetic resonance imaging data.

  24. Progression of cerebral small vessel disease in relation to risk factors and cognitive consequences: Rotterdam Scan study

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Stroke 2008-07-17 Vascular contributions

    Higher age, female sex, cigarette smoking, elevated blood pressure, and baseline lesion load were associated with small vessel disease progression.

  25. Impact of white matter hyperintensity volume progression on rate of cognitive and motor decline

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Neurology 2008-07-01 Caregiving

    Increased total and periventricular (PV) white matter hyperintensity (WMH) burden and progression of PV WMH burden are associated with decreased gait performance over time, while progression of subcortical WMH volume is associated with memory decline in cognitively intact elderly.

  26. The cost of cerebral ischaemia

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Neuropharmacology 2008-06-05 Vascular contributions

    Cerebral ischaemia is a major cause of disability and death globally and has a profoundly negative impact on the individuals it affects, those that care for them and society as a whole.

  27. Hypertension and cerebrovascular dysfunction

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Cell metabolism 2008-06-01 Risk factors

    Essential hypertension has devastating effects on the brain, being the major cause of stroke and a leading cause of dementia.

  28. Microbleed topography, leukoaraiosis, and cognition in probable Alzheimer disease from the Sunnybrook dementia study

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Archives of neurology 2008-06-01 Vascular contributions

    Occipital predominance of microbleeds with corresponding parietooccipital leukoaraiosis has not been well described in prior imaging studies of AD.

  29. Prevalence of idiopathic normal-pressure hydrocephalus in the elderly population of a Japanese rural community

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Neurologia medico-chirurgica 2008-05-01 Disparities

    The prevalence of idiopathic normal-pressure hydrocephalus (NPH) in a community was investigated by retrospective analysis of data from a previous community-based study of 170 randomly selected elderly residents aged 65 years or older.

  30. Vascular subcortical hyperintensities predict conversion to vascular and mixed dementia in MCI patients

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Stroke 2008-04-24 Brain scans and imaging

    The risk of vascular or mixed dementia, but not of other types of dementia, was significantly increased in MCI patients with a large amount of subcortical hyperintensities at baseline.

  31. Unrecognized myocardial infarction in relation to risk of dementia and cerebral small vessel disease

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Stroke 2008-03-06 Long-term cohort studies

    Men, but not women, with unrecognized myocardial infarction (MI) have an increased risk of cardiac events and stroke compared with those without MI or with recognized MI.

  32. Vascular cognitive impairment: current concepts and clinical developments

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. The Lancet. Neurology 2008-03-01 Vascular contributions

    Vascular cognitive impairment (VCI) comprises a range of cognitive disorders related to cerebral vessel disease and has generally replaced the term multi-infarct dementia.

  33. Abnormal regional cerebral blood flow in cognitively normal elderly subjects with hypertension

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Stroke 2008-01-03 Brain scans and imaging

    Cognitively normal subjects with HTN (n=19) had decreased rCBF in the putamen, globus pallidus, bilaterally, and in the left hippocampus compared with normotensives (n=22).

  34. Brain volume decline in aging: evidence for a relation between socioeconomic status, preclinical Alzheimer disease, and reserve

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Archives of neurology 2008-01-01 Brain scans and imaging

    Cross-sectional and longitudinal observation.

  35. Diffusion tensor imaging (DTI)-based white matter mapping in brain research: a review

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of molecular neuroscience : MN 2008-01-01 Vascular contributions

    Diffusion tensor imaging (DTI) has become one of the most popular MRI techniques in brain research, as well as in clinical practice.

  36. Magnetic resonance imaging white matter hyperintensities and brain volume in the prediction of mild cognitive impairment and dementia

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. Archives of neurology 2008-01-01 Brain scans and imaging

    High WMH was a predictor of progression from normal to MCI (adjusted hazard ratio [HR], 3.30; 95% confidence interval [CI], 1.33-8.17; P= .01) but not conversion from MCI to all-cause dementia.

  37. The clinical diagnostic utility of transcranial magnetic stimulation: report of an IFCN committee

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2007-12-11 Vascular contributions

    The review focuses on the clinical diagnostic utility of transcranial magnetic stimulation (TMS).

  38. Incidence and prognosis of transient neurological attacks

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. JAMA 2007-12-01 Long-term cohort studies

    Transient neurological attacks (TNAs) are attacks with temporary ( Objective To study the incidence and prognosis of focal TNAs (or TIAs), nonfocal TNAs, and mixed TNAs.

  39. Gait variability is associated with subclinical brain vascular abnormalities in high-functioning older adults

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Neuroepidemiology 2007-11-27 Caregiving

    In this group of older adults free from neurodegenerative diseases, a greater variability of step length was associated with greater burden of subclinical brain vascular abnormalities as defined by MRI.

  40. Phase lag index: assessment of functional connectivity from multi channel EEG and MEG with diminished bias from common sources

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Human brain mapping 2007-11-01 Brain scans and imaging

    The PLI performed at least as well as the PC in detecting true changes in synchronization in model and real data but, at the same token and like-wise the IC, it was much less affected by the influence of common sources and active reference electrodes.

  41. Chronic kidney disease is associated with white matter hyperintensity volume: the Northern Manhattan Study (NOMAS)

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Stroke 2007-10-25 Prevention and risk

    The association between moderate-severe chronic kidney disease and white matter hyperintensity volume highlights the growing importance of kidney disease as a possible determinant of cerebrovascular disease and/or as a marker of microangiopathy.

  42. The hemo-neural hypothesis: on the role of blood flow in information processing

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of neurophysiology 2007-10-03 Vascular contributions

    Brain vasculature is a complex and interconnected network under tight regulatory control that exists in intimate communication with neurons and glia.

  43. Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. BMC medical genetics 2007-09-19 Vascular contributions

    Our results suggest that genes associated with clinical neurological disease also have detectable effects on subclinical phenotypes.

  44. Blood-brain barrier: ageing and microvascular disease--systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Neurobiology of aging 2007-09-14 Lewy body dementia

    Cerebral "microvascular" disease occurs in lacunar stroke, leukoaraiosis, vascular dementia and Alzheimer's disease.

  45. Silent brain infarcts: a systematic review

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. The Lancet. Neurology 2007-07-01 Vascular contributions

    As the availability and quality of imaging techniques improve, doctors are identifying more patients with no history of transient ischaemic attack or stroke in whom imaging shows brain infarcts.

  46. Association of ambulatory blood pressure with ischemic brain injury

    ✓ Peer-reviewed alzhub usefulness score 42 out of 100. Hypertension (Dallas, Tex. : 1979) 2007-04-02 Disparities

    Cerebral white matter hyperintensities on brain MRI (leukoaraiosis) are associated with increased risk of stroke and dementia.

  47. Cognitive disorders in acute stroke: prevalence and clinical determinants

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Cerebrovascular diseases (Basel, Switzerland) 2007-04-02 Vascular contributions

    Cognitive impairment is common in the first weeks after stroke, with executive and perceptual disorders being the most frequent.

  48. Course of cerebral amyloid angiopathy-related inflammation

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. Neurology 2007-04-01 Genetics

    Baseline MRI scans were characterized by asymmetric T2-hyperintense lesions extending to the subcortical white matter and occasionally the overlying gray matter, with signal properties suggesting vasogenic edema.

  49. Inflammatory biomarkers are associated with total brain volume: the Framingham Heart Study

    ✓ Peer-reviewed alzhub usefulness score 56 out of 100. Neurology 2007-03-01 Brain scans and imaging

    Systemic inflammation is associated with ischemia and Alzheimer disease (AD).

  50. Aging effects on cerebral blood and cerebrospinal fluid flows

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007-02-21 Vascular contributions

    Phase-contrast magnetic resonance imaging (PC-MRI) is a noninvasive reliable technique, which enables quantification of cerebrospinal fluid (CSF) and total cerebral blood flows (tCBF).

From across this tag

9 of the 902 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 9. The same 9 appear here every time.

All topic tags with their study counts