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Newest in this topic

  1. Alcohol use disorder accelerates age-related cognitive decline 2026-09-23
  2. A longitudinal study of age-related traits and cognitive function: The Collaborative Amish Aging and Memory Project (CAAMP) 2026-09-20
  3. Associations of menopause hormone therapy with late-life cognition and brain health vary by formulation and APOEε4 presence 2026-09-20

Studies

1,138 studies carry this tag.

Date range

1986 to 2026

Top journals

  • Alzheimer s & Dementia 42
  • Neurology 41
  • Journal of the American Geriatrics Society 36
  • Journal of Alzheimer's disease : JAD 33
  • Nutrients 23

437 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Cognitive deficits in people who have recovered from COVID-19

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. EClinicalMedicine 2021-07-23 How common it is

    People who had recovered from COVID-19, including those no longer reporting symptoms, exhibited significant cognitive deficits versus controls when controlling for age, gender, education level, income, racial-ethnic group, pre-existing medical disorders, tiredness, depression and anxiety.

  2. Post-infection cognitive impairments in a cohort of elderly patients with COVID-19

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Molecular neurodegeneration 2021-07-19 Clinical safety

    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with an increased risk of long-term cognitive decline in elderly population.

  3. A Critical Review of the Study of Neuroprotective Diets to Reduce Cognitive Decline

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Nutrients 2021-06-30 Prevention trials

    Alzheimer's disease (AD) and other dementias are now the seventh leading cause of death in the world and are projected to affect 115.4 million people by 2050.

  4. A double-blind randomized controlled trial combining cognitive training (CoRe) and neurostimulation (tDCS) in the early stages of cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 76 out of 100. Aging clinical and experimental research 2021-06-22 Prevention trials

    Combined multi-domain interventions may contribute to preventing or delaying disease progression.

  5. Nineteen cross-sectional studies that investigated 19.734 community-dwelling and institutionalized older adults free of disability and dementia were included.

  6. We aimed to evaluate the feasibility of multidomain intervention (MI) tailored to the Korean context.

  7. Association of late-life depression with cognitive impairment: evidence from a cross-sectional study among older adults in India

    ✓ Peer-reviewed alzhub usefulness score 63 out of 100. BMC geriatrics 2021-06-15 Disparities

    Depression is linked to an increased risk of cognitive decline and dementia; therefore, failing to diagnose and treat LLD in later life may have significant health implications.

  8. The role of the medial prefrontal cortex in cognition, ageing and dementia

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Brain communications 2021-06-11 Disparities

    Although, anatomical disparities of the rodent medial prefrontal cortex compared to the primate homologue are apparent, current rodent models have effectively implicated the medial prefrontal cortex as a neural substrate of cognitive decline within ageing and dementia.

  9. A Fay-Herriot Model for Estimating Subjective Cognitive Decline among Military Veterans

    ✓ Peer-reviewed alzhub usefulness score 34 out of 100. The Journal of Prevention of Alzheimer s Disease 2021-05-31 Risk factors

    Direct survey-weighted rates were correlated with model-predicted rates in 43 counties (Pearson r = 0.32).

  10. Effects of Aerobic Exercise Training on Systemic Biomarkers and Cognition in Late Middle-Aged Adults at Risk for Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Frontiers in endocrinology 2021-05-20 Prevention and risk

    Increasing evidence indicates that physical activity and exercise training may delay or prevent the onset of Alzheimer's disease (AD).

  11. MIND diet and cognitive performance in older adults: a systematic review

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Critical reviews in food science and nutrition 2021-05-14 Prevention trials

    Cognitive decline is a rapidly increasing public health concern.

  12. Digital Biomarkers of Cognitive Frailty: The Value of Detailed Gait Assessment Beyond Gait Speed

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Gerontology 2021-05-10 Digital health tools

    Dual-task gait and other detailed gait metrics provide value for identifying CF above gait speed alone.

  13. Effect of Cognitive Training in Fully Immersive Virtual Reality on Visuospatial Function and Frontal-Occipital Functional Connectivity in Predementia: Randomized Controlled Trial

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Journal of medical Internet research 2021-05-06 Prevention trials

    However, the results of recent studies using semi-immersive virtual reality (VR)-assisted cognitive training are inconsistent.

  14. A Systematic Review and Meta-Analysis of Cognitive Training in Adults with Major Depressive Disorder

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Neuropsychology review 2021-04-28 Prevention trials

    Major Depressive Disorder (MDD) is common and disabling, and is linked to functional impairment and increased mortality.

  15. A Scoping Review of Cognitive Training in Neurodegenerative Diseases via Computerized and Virtual Reality Tools: What We Know So Far

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Brain sciences 2021-04-21 Prevention trials

    Most prevalent neurodegenerative diseases such as Alzheimer's disease, frontotemporal dementia, Parkinson's disease and multiple sclerosis are heterogeneous in their clinical profiles and underlying pathophysiology, although they typically share the presence of cognitive impairment that worsens significantly during the course of the disease.

  16. Association of Neighborhood Context, Cognitive Decline, and Cortical Change in an Unimpaired Cohort

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Neurology 2021-04-14 Brain scans and imaging

    In this longitudinal study of cognitively unimpaired adults, living in the most highly disadvantaged neighborhoods was associated with accelerated degeneration in Alzheimer signature regions and cognitive decline.

  17. Prevention of cognitive decline in subjective cognitive decline APOE ε4 carriers after EGCG and a multimodal intervention (PENSA): Study design

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. Alzheimer's & dementia (New York, N. Y.) 2021-03-31 Treatments

    The use of new technologies (i.e., mobile ecological momentary assessments [EMAs], activity tracker) in the PENSA study allows the collection of continuous data on lifestyle behaviors (diet and physical activity) and mood, enabling a personalized design as well as an intensive follow-up of participants.

  18. Mitigating the negative impacts of aging on cognitive function; modifiable factors associated with increasing cognitive reserve

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. The European journal of neuroscience 2021-03-26 Prevention trials

    Research suggests that social, physical, and cognitively challenging activities during lifetime, could mitigate the negative effects of aging on cognitive function.

  19. Α Virtual Reality App for Physical and Cognitive Training of Older People With Mild Cognitive Impairment: Mixed Methods Feasibility Study

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. JMIR serious games 2021-03-24 Prevention trials

    However, to replace existing nonpharmaceutical treatment training protocols, VR platforms need significant improvement if they are to appeal to older people with symptoms of cognitive decline and meet their specific needs.

  20. Efficacy of Multidomain Intervention Against Physio-cognitive Decline Syndrome: A Cluster-randomized Trial

    ✓ Peer-reviewed alzhub usefulness score 79 out of 100. Archives of gerontology and geriatrics 2021-03-13 Prevention trials

    Backgrounds To investigate the efficacy of a community group-based intervention among community-dwelling older adults with physio-cognitive decline syndrome (PCDS).

  21. Sex differences and the role of education in cognitive ageing: analysis of two UK-based prospective cohort studies

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. The Lancet. Public health 2021-02-01 Disparities

    Our findings suggest that decreasing disparities between sexes in education, due to secular increases in educational opportunities, could attenuate sex differences in dementia risk and cognitive decline in the future.

  22. Sex Differences in Cognitive Decline Among US Adults

    ✓ Peer-reviewed alzhub usefulness score 75 out of 100. JAMA network open 2021-02-01 Getting a diagnosis

    Among 34 349 participants, 26 088 who self-reported Black or White race, were free of stroke and dementia, and had covariate data at or before the first cognitive assessment were included for analysis.

  23. Past, Present, and Future of Non-invasive Brain Stimulation Approaches to Treat Cognitive Impairment in Neurodegenerative Diseases: Time for a Comprehensive Critical Review

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Frontiers in aging neuroscience 2021-01-20 Prevention trials

    We here review evidence gathered for nearly a decade on non-invasive brain stimulation (NIBS), a less known therapeutic strategy aiming to limit cognitive decline associated with neurodegenerative conditions.

  24. Impact of Combined Photo-Biomodulation and Aerobic Exercise on Cognitive Function and Quality-of-Life in Elderly Alzheimer Patients with Anemia: A Randomized Clinical Trial

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. International journal of general medicine 2021-01-14 Treatments

    Clinical trial registration www.

  25. Alzheimer's dementia (AD) is the sixth leading cause of death in the U.S., with an estimated $305 billion cost of care in 2020.

  26. Unhealthy foods may attenuate the beneficial relation of a Mediterranean diet to cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2021-01-07 Prevention trials

    This prospective study found that high consumption of Western diet components attenuates benefits of the MedDiet on cognition.

  27. Acceptance and Usability of Immersive Virtual Reality in Older Adults with Objective and Subjective Cognitive Decline

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Journal of Alzheimer's disease : JAD 2021-01-01 Prevention trials

    Immersive VR was acceptable and enjoyable for older adults in both groups.

  28. Cognitive Effects of Aerobic Exercise in Alzheimer's Disease: A Pilot Randomized Controlled Trial

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Journal of Alzheimer's disease : JAD 2021-01-01 Cognitive tests and assessment

    Aerobic exercise has shown inconsistent cognitive effects in older adults with Alzheimer's disease (AD) dementia.

  29. Interactions Between Age, Sex, Menopause, and Brain Structure at Midlife: A UK Biobank Study

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. The Journal of clinical endocrinology and metabolism 2021-01-01 Long-term cohort studies

    Age and female sex are risk factors for dementia, and menopause is associated with cognitive dysfunction.

  30. Mind Diet Adherence and Cognitive Performance in the Framingham Heart Study

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Journal of Alzheimer's disease : JAD 2021-01-01 Long-term cohort studies

    Adherence to the Mediterranean-DASH for Neurodegenerative Delay (MIND) diet has previously been associated with cognitive decline and dementia.

  31. MIND Diet, Common Brain Pathologies, and Cognition in Community-Dwelling Older Adults

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. Journal of Alzheimer's disease : JAD 2021-01-01 Prevention trials

    MIND diet is associated with better cognitive functioning independently of common brain pathology, suggesting that the MIND diet may contribute to cognitive resilience in the elderly.

  32. Multidomain Intervention for Reversal of Cognitive Frailty, Towards a Personalized Approach (AGELESS Trial): Study Design

    ✓ Peer-reviewed alzhub usefulness score 79 out of 100. Journal of Alzheimer's disease : JAD 2021-01-01 Prevention trials

    This project will be part of the World-Wide FINGERS (Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability) Network, of which common identifiable data will be shared and harmonized among the consortia.

  33. Nutrition to Prevent or Treat Cognitive Impairment in Older Adults: A GRADE Recommendation

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. The journal of prevention of Alzheimer's disease 2021-01-01 Prevention trials

    Aging is associated with cognitive declines leading to mild cognitive impairments or Alzheimer disease.

  34. Physio-Cognitive Decline Syndrome as the Phenotype and Treatment Target of Unhealthy Aging

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. The journal of nutrition, health & aging 2021-01-01 Prevention trials

    In this era of unprecedented longevity, healthy aging is an important public health priority.

  35. Promoting Successful Cognitive Aging: A Ten-Year Update

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. Journal of Alzheimer's disease : JAD 2021-01-01 Prevention and risk

    A decade has passed since we published a comprehensive review in this journal addressing the topic of promoting successful cognitive aging, making this a good time to take stock of the field.

  36. The Effect of Baseline Performance and Age on Cognitive Training Improvements in Older Adults: A Qualitative Review

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. The journal of prevention of Alzheimer's disease 2021-01-01 Prevention trials

    However, individuals participating in training regimens differ greatly with respect to their outcomes, demonstrating the importance of considering individual differences, in particular age and baseline performance in a cognitive domain, when evaluating the effectiveness of cognitive training.

  37. Trajectories of Cognitive and Motor Function Between Ages 45 and 90 Years: A Population-Based Study

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. The journals of gerontology. Series A, Biological sciences and medical sciences 2021-01-01 Long-term cohort studies

    Between 1997 and 2016, we repeatedly assessed cognitive function with 5 tests in 9514 participants aged 45-90 years from the population-based Rotterdam Study.

  38. In mild cognitive impairment (MCI) due to Alzheimer disease (AD), also known as prodromal AD, there is evidence for a pathologic shortage of uridine, choline, and docosahexaenoic acid [DHA]), which are key nutrients needed by the brain.

  39. Balance and gait performance in older adults with early-stage cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 46 out of 100. European journal of physical and rehabilitation medicine 2020-12-01 Digital health tools

    It is a piece of evidence that cognitive dysfunction, even in early stage of memory decline, may have some bad impact on balance and gait regardless of the effect of musculoskeletal problems.

  40. Neighborhood disadvantage is associated with accelerated cortical thinning and cognitive decline in cognitively unimpaired adults

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Alzheimer s & Dementia 2020-12-01 Risk factors

    Exposure to high neighborhood‐level socioeconomic disadvantage is associated with negative health outcomes.

  41. Combined physical and cognitive training for older adults with and without cognitive impairment: A systematic review and network meta-analysis of randomized controlled trials

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Ageing research reviews 2020-11-26 Prevention trials

    Combining physical exercise with cognitive training is a popular intervention in dementia prevention trials and guidelines.

  42. A critical review of the epidemiological evidence of effects of air pollution on dementia, cognitive function and cognitive decline in adult population

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. The Science of the total environment 2020-11-25 Caregiving

    Cognitive decline and dementia incidence have also been consistently associated with exposure to air pollution.

  43. Kidney Function and Cognitive Decline in Older Adults: Examining the Role of Neurodegeneration

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Journal of the American Geriatrics Society 2020-11-20 Treatments

    Median (IQR) eGFR was 73(60-84) mL/min/1.73 m 2 .

  44. Association of Delirium With Long-term Cognitive Decline: A Meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 76 out of 100. JAMA neurology 2020-11-01 Risk factors

    Of 1583 articles, data subjected from the 24 studies (including 3562 patients who experienced delirium and 6987 controls who did not) were included in a random-effects meta-analysis for pooled effect estimates and random-effects meta-regressions to identify sources of study variance.

  45. Intervention participants with MCI self-reported, or demonstrated, improved functioning across a range of cognitive (global cognitive function, executive function, processing speed, memory, attention, mood, emotion, motivation, brain cortex, orientation), and physical (gait, balance, mobility) outcomes.

  46. Effect of 1 Year of Qigong Exercise on Cognitive Function Among Older Chinese Adults at Risk of Cognitive Decline: A Cluster Randomized Controlled Trial

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Frontiers in psychology 2020-10-30 Treatments

    Twenty-five of 33 (75.8%) participants in the qigong group and 26 of 33 (78.8%) participants in the control group completed the 1-year exercise programs.

  47. A ketogenic drink improves cognition in mild cognitive impairment: Results of a 6-month RCT

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2020-10-26 Mild cognitive impairment

    This kMCT drink improved cognitive outcomes in MCI, at least in part by increasing blood ketone level.

  48. A total of 887 (69.5%) participants reported incident difficulty in at least one IADL task category.

  49. The Impact of COVID-19 Infection and Enforced Prolonged Social Isolation on Neuropsychiatric Symptoms in Older Adults With and Without Dementia: A Review

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Frontiers in psychiatry 2020-10-22 Clinical safety

    Fifteen articles were included: 8 focussed on the psychiatric symptoms caused by the COVID-19 infection and 7 investigated the impact of social isolation on older adults' neuropsychiatric symptoms.

  50. The Effect of Adherence to the Mediterranean Diet on Late-Life Cognitive Disorders: A Systematic Review

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Journal of the American Medical Directors Association 2020-10-01 Prevention trials

    The review's analysis confirmed that adherence to the MedDiet is associated with some improvement in cognitive health.

From across this tag

10 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 10. The same 10 appear here every time.

All topic tags with their study counts