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Home › Research › Topics › roles

roles

8 studies tagged roles, dated 2003-04-01 to 2024-01-01. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease 2024-01-01
  2. Roles of TREM2 in the Pathological Mechanism and the Therapeutic Strategies of Alzheimer's Disease 2024-01-01
  3. Characteristics of plaque lipid-associated macrophages and their possible roles in the pathogenesis of atherosclerosis 2022-08-03

Studies

8 studies carry this tag.

Date range

2003 to 2024

Top journals

  • Current opinion in lipidology 1
  • Frontiers in cellular neuroscience 1
  • International journal of geriatric psychiatry 1
  • Neurochemical research 1
  • Physiological reviews 1

8 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Physiological reviews 2024-01-01 Genetics

    Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms, among which oxidative stress (OS) appears as a major determinant.

  2. Roles of TREM2 in the Pathological Mechanism and the Therapeutic Strategies of Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. The journal of prevention of Alzheimer's disease 2024-01-01 TREM2 and immune genetics

    Alzheimer's disease (AD) is an age-related degenerative disease, which is characteristic by the deposition of senile plaques (SP) outside the cells, the neurofibrillary tangles (NFTs) inside the neurons, and the loss of synapse and neurons.

  3. Characteristics of plaque lipid-associated macrophages and their possible roles in the pathogenesis of atherosclerosis

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Current opinion in lipidology 2022-08-03 TREM2 and immune genetics

    Recent findings from single-cell transcriptomic studies prompted us to revisit the role of plaque foamy macrophages in the pathogenesis of atherosclerosis.

  4. Possible Neuropathology of Sleep Disturbance Linking to Alzheimer's Disease: Astrocytic and Microglial Roles

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Frontiers in cellular neuroscience 2022-06-09 TREM2 and immune genetics

    Sleep disturbances not only deteriorate Alzheimer's disease (AD) progress by affecting cognitive states but also accelerate the neuropathological changes of AD.

  5. Mechanistic insights into the deleterious roles of Nasu-Hakola disease associated TREM2 variants

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Scientific reports 2020-02-27 TREM2 and immune genetics

    Recently, the critical roles played by genetic variants of TREM2 (Triggering Receptor Expressed on Myeloid cells 2) in Alzheimer's disease have been aggressively highlighted.

  6. Roles of serum fibrinogen α chain-derived peptides in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. International journal of geriatric psychiatry 2013-11-05 Biomarkers

    The profile of 10 FIBA-derived peptides combined with age would be a candidate biomarker for AD, which facilitates screening of the disease.

  7. Evolution in health and medicine Sackler colloquium: Evolution of the human lifespan and diseases of aging: roles of infection, inflammation, and nutrition

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2009-12-04 Genetics

    Humans have evolved much longer lifespans than the great apes, which rarely exceed 50 years.

  8. Cholinesterases: new roles in brain function and in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurochemical research 2003-04-01 Tau biomarkers

    The most important therapeutic effect of cholinesterase inhibitors (ChEI) on approximately 50% of Alzheimer's disease (AD) patients is to stabilize cognitive function at a steady level during a 1-year period of treatment as compared to placebo.

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