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Home › Research › Topics › microglial

microglial

4 studies tagged microglial, dated 2018-02-26 to 2023-05-10. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Neuroinflammation in Alzheimer's disease: microglial signature and their relevance to disease 2023-05-10
  2. Microglial efferocytosis: Diving into the Alzheimer's disease gene pool 2022-11-01
  3. 25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner 2020-06-17

Studies

4 studies carry this tag.

Date range

2018 to 2023

Top journals

  • Genome medicine 1
  • Inflammation and regeneration 1
  • Journal of neuroinflammation 1
  • Neuron 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Neuroinflammation in Alzheimer's disease: microglial signature and their relevance to disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Inflammation and regeneration 2023-05-10 Genetics

    Alzheimer's disease (AD) is the most common form of dementia, pathologically characterized by senile plaques and neurofibrillary tangles (NFTs), resulting in neurodegeneration.

  2. Microglial efferocytosis: Diving into the Alzheimer's disease gene pool

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Neuron 2022-11-01 Genetics

    Genome-wide association studies and functional genomics studies have linked specific cell types, genes, and pathways to Alzheimer's disease (AD) risk.

  3. 25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of neuroinflammation 2020-06-17 Genetics

    25-HC may function as a microglial-secreted inflammatory mediator in the brain, promoting IL-1β-mediated neuroinflammation in an apoE isoform-dependent manner (E4>>E2/E3) and thus may be an important mediator of neuroinflammation in AD.

  4. Genetic risk for Alzheimer's disease is concentrated in specific macrophage and microglial transcriptional networks

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Genome medicine 2018-02-26 Genetics

    AD risk single nucleotide polymorphisms (SNPs) are preferentially located at sites of open chromatin in immune cells, particularly monocytes (z score = 4.43; corrected P = 5.88 × 10 - 3 ).

All topic tags with their study counts