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Newest in this topic

  1. Diagnosis of cognitive impairment and dementia: blood plasma and optical coherence tomography 2024-12-27
  2. Optical coherence tomography as retinal imaging biomarker of neuroinflammation/neurodegeneration in systemic disorders in adults and children 2022-04-15
  3. Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by longitudinal intravital two-photon microscopy and optical coherence tomography 2021-02-05

Studies

18 studies carry this tag.

Date range

2010 to 2024

Top journals

  • Journal of Alzheimer's disease : JAD 2
  • The British journal of ophthalmology 2
  • Acta ophthalmologica 1
  • Alzheimer's & dementia (Amsterdam, Netherlands) 1
  • American journal of physiology. Heart and circulatory physiology 1

16 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Diagnosis of cognitive impairment and dementia: blood plasma and optical coherence tomography

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. Brain communications 2024-12-27 Biomarkers

    After adjusting for retinal scan signal strength, neurofilament light chain showed a stronger negative association with retinal nerve fibre layer thickness [standardized beta estimate ( β ) = -0.184] and ganglion cell-inner plexiform layer thickness ( β = -0.139) compared to phosphorylated tau181, which exhibited weaker associations with ganglion cell-inner plexiform layer ( β = -0.091) and retinal nerve fibre layer ( β = -0.059).

  2. Optical coherence tomography as retinal imaging biomarker of neuroinflammation/neurodegeneration in systemic disorders in adults and children

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Eye (London, England) 2022-04-15 Brain scans and imaging

    The retina and the optic nerve are considered extensions of the central nervous system (CNS) and thus can serve as the window for evaluation of CNS disorders.

  3. Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by longitudinal intravital two-photon microscopy and optical coherence tomography

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. American journal of physiology. Heart and circulatory physiology 2021-02-05 Brain scans and imaging

    Age-related blood-brain barrier (BBB) disruption and cerebromicrovascular rarefaction contribute importantly to the pathogenesis of both vascular cognitive impairment and dementia (VCID) and Alzheimer's disease (AD).

  4. Decreased Retinal Vascular Density in Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI): An Optical Coherence Tomography Angiography (OCTA) Study

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Frontiers in aging neuroscience 2021-01-15 Brain scans and imaging

    The superficial vascular density in the AD and MCI patient groups was significantly lower than that in the HC group.

  5. Optical Coherence Tomography Angiography in Neurodegenerative Diseases: A Review

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Eye and brain 2020-07-14 Brain scans and imaging

    Optical coherence tomography angiography (OCT-A) has emerged as a novel, fast, safe and non-invasive imaging technique of analyzing the retinal and choroidal microvasculature in vivo.

  6. Retinal microvascular attenuation in mental cognitive impairment and Alzheimer's disease by optical coherence tomography angiography

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Acta ophthalmologica 2020-03-09 Brain scans and imaging

    Our findings demonstrated the macular microvascular attenuation in MCI and AD patients.

  7. Comparison of Retinal Microvasculature in Patients With Alzheimer's Disease and Primary Open-Angle Glaucoma by Optical Coherence Tomography Angiography

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Investigative ophthalmology & visual science 2019-08-01 Brain scans and imaging

    AD and POAG are neurodegenerative diseases associated with apoptosis of nerve cells and impairment of microvasculature.

  8. Optical coherence tomography angiography in preclinical Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. The British journal of ophthalmology 2019-05-22 Brain scans and imaging

    Retinal vessel density was higher in individuals with preclinical AD.

  9. Retinal layers in Parkinson's disease: A meta-analysis of spectral-domain optical coherence tomography studies

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Parkinsonism & related disorders 2019-04-30 Brain scans and imaging

    Parkinson's patients show significant thinning of the inner retinal layers, resembling changes found in glaucoma and other neurodegenerative diseases like Alzheimer's. Study of different cell layers in-vivo is possible by moving from time-to spectral domain OCT.

  10. Evaluation of Ocular Perfusion in Alzheimer's Disease Using Optical Coherence Tomography Angiography

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of Alzheimer's disease : JAD 2018-01-01 Brain scans and imaging

    Patients with AD showed a reduced flow density in the radial peripapillary capillaries layer and in the superficial retinal OCT angiogram when compared with healthy controls.

  11. Patterns of Retinal Ganglion Cell Damage in Neurodegenerative Disorders: Parvocellular vs Magnocellular Degeneration in Optical Coherence Tomography Studies

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Frontiers in neurology 2017-12-22 Brain scans and imaging

    Many neurodegenerative disorders, such as Parkinson's disease (PD) and Alzheimer's disease (AD), are characterized by loss of retinal ganglion cells (RGCs) as part of the neurodegenerative process.

  12. Optical Coherence Tomography as a Biomarker for Diagnosis, Progression, and Prognosis of Neurodegenerative Diseases

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Journal of ophthalmology 2016-10-20 Brain scans and imaging

    Neurodegenerative diseases present a current challenge for accurate diagnosis and for providing precise prognostic information.

  13. Optical coherence tomography angiography: an overview of the technology and an assessment of applications for clinical research

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. The British journal of ophthalmology 2016-10-04 Brain scans and imaging

    In recent years, ophthalmology has experienced significant developments with respect to imaging modalities.

  14. A systematic review and meta-analysis of retinal nerve fiber layer change in dementia, using optical coherence tomography

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Alzheimer's & dementia (Amsterdam, Netherlands) 2015-04-23 Brain scans and imaging

    OCT measurement of RNFL thickness appears diagnostically useful in discriminating between AD, or MCI, and HC.

  15. Retinal neurodegeneration on optical coherence tomography and cerebral atrophy

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Neuroscience letters 2014-10-19 Brain scans and imaging

    Neurodegeneration in dementia is mainly evaluated by assessing cerebral atrophy, while retinal neurodegeneration can be quantified in vivo using optical coherence tomography (OCT).

  16. Evaluation of the chorioretinal thickness changes in Alzheimer's disease using spectral-domain optical coherence tomography

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Clinical & experimental ophthalmology 2014-08-15 Brain scans and imaging

    Patients with AD had chorioretinal structural alterations.

  17. Choroidal thinning as a new finding in Alzheimer's disease: evidence from enhanced depth imaging spectral domain optical coherence tomography

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Journal of Alzheimer's disease : JAD 2014-01-01 Brain scans and imaging

    Compared with healthy subjects, patients with AD showed a significant reduction in choroidal thickness.

  18. Optical coherence tomography of the retina: applications in neurology

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Current opinion in neurology 2010-02-01 Brain scans and imaging

    This review summarizes the mechanisms and recent developments of optical coherence tomography and its practical uses in neurology.

All topic tags with their study counts