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optical-coherence
18 studies tagged optical-coherence, dated 2010-02-01 to 2024-12-27. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Diagnosis of cognitive impairment and dementia: blood plasma and optical coherence tomography 2024-12-27
- Optical coherence tomography as retinal imaging biomarker of neuroinflammation/neurodegeneration in systemic disorders in adults and children 2022-04-15
- Demonstration of age-related blood-brain barrier disruption and cerebromicrovascular rarefaction in mice by longitudinal intravital two-photon microscopy and optical coherence tomography 2021-02-05
Studies
18 studies carry this tag.
Date range
2010 to 2024
Top journals
- Journal of Alzheimer's disease : JAD 2
- The British journal of ophthalmology 2
- Acta ophthalmologica 1
- Alzheimer's & dementia (Amsterdam, Netherlands) 1
- American journal of physiology. Heart and circulatory physiology 1
16 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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69/100
After adjusting for retinal scan signal strength, neurofilament light chain showed a stronger negative association with retinal nerve fibre layer thickness [standardized beta estimate ( β ) = -0.184] and ganglion cell-inner plexiform layer thickness ( β = -0.139) compared to phosphorylated tau181, which exhibited weaker associations with ganglion cell-inner plexiform layer ( β = -0.091) and retinal nerve fibre layer ( β = -0.059).
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The retina and the optic nerve are considered extensions of the central nervous system (CNS) and thus can serve as the window for evaluation of CNS disorders.
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Age-related blood-brain barrier (BBB) disruption and cerebromicrovascular rarefaction contribute importantly to the pathogenesis of both vascular cognitive impairment and dementia (VCID) and Alzheimer's disease (AD).
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The superficial vascular density in the AD and MCI patient groups was significantly lower than that in the HC group.
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Optical coherence tomography angiography (OCT-A) has emerged as a novel, fast, safe and non-invasive imaging technique of analyzing the retinal and choroidal microvasculature in vivo.
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Our findings demonstrated the macular microvascular attenuation in MCI and AD patients.
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AD and POAG are neurodegenerative diseases associated with apoptosis of nerve cells and impairment of microvasculature.
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Retinal vessel density was higher in individuals with preclinical AD.
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Parkinson's patients show significant thinning of the inner retinal layers, resembling changes found in glaucoma and other neurodegenerative diseases like Alzheimer's. Study of different cell layers in-vivo is possible by moving from time-to spectral domain OCT.
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45/100
Patients with AD showed a reduced flow density in the radial peripapillary capillaries layer and in the superficial retinal OCT angiogram when compared with healthy controls.
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Many neurodegenerative disorders, such as Parkinson's disease (PD) and Alzheimer's disease (AD), are characterized by loss of retinal ganglion cells (RGCs) as part of the neurodegenerative process.
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Neurodegenerative diseases present a current challenge for accurate diagnosis and for providing precise prognostic information.
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In recent years, ophthalmology has experienced significant developments with respect to imaging modalities.
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OCT measurement of RNFL thickness appears diagnostically useful in discriminating between AD, or MCI, and HC.
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Neurodegeneration in dementia is mainly evaluated by assessing cerebral atrophy, while retinal neurodegeneration can be quantified in vivo using optical coherence tomography (OCT).
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Patients with AD had chorioretinal structural alterations.
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Compared with healthy subjects, patients with AD showed a significant reduction in choroidal thickness.
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This review summarizes the mechanisms and recent developments of optical coherence tomography and its practical uses in neurology.