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Newest in this topic

  1. The role of age on tau PET uptake and gray matter atrophy in atypical Alzheimer's disease 2019-03-08
  2. The design and progress of a multidomain lifestyle intervention to improve brain health in middle-aged persons to reduce later Alzheimer's disease risk: The Gray Matters randomized trial 2015-05-16
  3. Frontobasal gray matter loss is associated with the TREM2 p.R47H variant 2014-06-17

Studies

9 studies carry this tag.

Date range

1989 to 2019

Top journals

  • Neurobiology of aging 2
  • Alzheimer's & dementia (New York, N. Y.) 1
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 1
  • Human brain mapping 1
  • NeuroImage 1

8 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. The role of age on tau PET uptake and gray matter atrophy in atypical Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2019-03-08 Brain scans and imaging

    Age is an important determinant of severity of cortical tau uptake in atypical AD, with young participants more likely to show widespread and severe cortical tau uptake.

  2. The design and progress of a multidomain lifestyle intervention to improve brain health in middle-aged persons to reduce later Alzheimer's disease risk: The Gray Matters randomized trial

    ✓ Peer-reviewed alzhub usefulness score 84 out of 100. Alzheimer's & dementia (New York, N. Y.) 2015-05-16 Cognitive tests and assessment

    Participants were empowered, learning that lifestyle might impact AD risk, exhibiting positive behavioral changes thus far.

  3. Frontobasal gray matter loss is associated with the TREM2 p.R47H variant

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Neurobiology of aging 2014-06-17 TREM2 and immune genetics

    A rare heterozygous TREM2 variant p.R47H (rs75932628) has been associated with an increased risk for Alzheimer's disease (AD).

  4. Covarying alterations in Aβ deposition, glucose metabolism, and gray matter volume in cognitively normal elderly

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Human brain mapping 2012-09-11 Brain scans and imaging

    β-Amyloid (Aβ), a feature of Alzheimer's disease (AD) pathology, may precede reduced glucose metabolism and gray matter (GM) volume and cognitive decline in patients with AD.

  5. White matter damage in Alzheimer disease and its relationship to gray matter atrophy

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Radiology 2010-12-21 Brain scans and imaging

    In AD, the observed patterns of WM abnormalities may reflect the advanced phase of a secondary degenerative process and an association, especially in the early phases of the disease, with primary WM tract damage over and above GM abnormalities.

  6. Relationships between hippocampal atrophy, white matter disruption, and gray matter hypometabolism in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2008-06-01 Brain scans and imaging

    In early Alzheimer's disease (AD), the hippocampal region is the area most severely affected by cellular and structural alterations, yet glucose hypometabolism predominates in the posterior association cortex and posterior cingulate gyrus.

  7. Voxel-based mapping of brain gray matter volume and glucose metabolism profiles in normal aging

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of aging 2007-07-13 Brain scans and imaging

    With age, the brain undergoes both structural and functional alterations, probably resulting in reported cognitive declines.

  8. A comprehensive study of gray matter loss in patients with Alzheimer's disease using optimized voxel-based morphometry

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. NeuroImage 2003-04-01 Tau biomarkers

    Voxel-based morphometry (VBM) has already been applied to MRI scans of patients with Alzheimer's disease (AD).

  9. Astrocytes in Alzheimer's disease gray matter express alpha 1-antichymotrypsin mRNA

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The American journal of pathology 1989-11-01 Biomarkers

    The serine protease inhibitor alpha 1-antichymotrypsin (ACT) has been shown to be tightly associated with the amyloid found in plaque cores and blood vessels in the brains of patients with Alzheimer's disease (AD).

All topic tags with their study counts