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Home › Research › Topics › alterations

alterations

7 studies tagged alterations, dated 1996-11-01 to 2023-01-05. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Clinical performance of an antibody-free assay for plasma Aβ42/Aβ40 to detect early alterations of Alzheimer's disease in individuals with subjective cognitive decline 2023-01-05
  2. Amelioration of cognitive impairments in APPswe/PS1dE9 mice is associated with metabolites alteration induced by total salvianolic acid 2017-03-30
  3. Identification of age- and disease-related alterations in circulating miRNAs in a mouse model of Alzheimer's disease 2015-02-19

Studies

7 studies carry this tag.

Date range

1996 to 2023

Top journals

  • Stroke 2
  • Alzheimer's research & therapy 1
  • Frontiers in cellular neuroscience 1
  • Hippocampus 1
  • Journal of the neurological sciences 1

6 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Clinical performance of an antibody-free assay for plasma Aβ42/Aβ40 to detect early alterations of Alzheimer's disease in individuals with subjective cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Alzheimer's research & therapy 2023-01-05 Biomarkers

    This study suggests that plasma Aβ42/Aβ40, as determined by this MS-based assay, has potential value as an accurate and cost-effective tool to identify individuals in the earliest stages of AD, supporting its implementation in clinical trials, preventative strategies and clinical practice.

  2. Amelioration of cognitive impairments in APPswe/PS1dE9 mice is associated with metabolites alteration induced by total salvianolic acid

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. PloS one 2017-03-30 Biomarkers

    TSA induced a remarkable amelioration of learning and memory impairments in APPswe/PS1dE9 mice through the regulation of Aβ42, Aβ40, carbohydrate and vitamin metabolites in the hippocampus and LDL-C and CHOL in the plasma.

  3. Identification of age- and disease-related alterations in circulating miRNAs in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Frontiers in cellular neuroscience 2015-02-19 Biomarkers

    Alzheimer's disease (AD) is a neurodegenerative disorder characterized clinically by the progressive decline of memory and cognition.

  4. Effect of hesperidin on neurobehavioral, neuroinflammation, oxidative stress and lipid alteration in intracerebroventricular streptozotocin induced cognitive impairment in mice

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of the neurological sciences 2014-11-06 Biomarkers

    Recent attention is given to the influence of dietary supplementation on health and mental well-being.

  5. Neuronal and glial alterations, increased anxiety, and cognitive impairment before hippocampal amyloid deposition in PDAPP mice, model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Hippocampus 2013-11-12 Biomarkers

    In the context of Alzheimer's disease (AD), hippocampal alterations have been well described in advanced stages of the pathology, when amyloid deposition, inflammation and glial activation occur, but less attention has been directed to studying early brain and behavioral changes.

  6. Alterations in glia and axons in the brains of Binswanger's disease patients

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Stroke 1997-07-01 Biomarkers

    The pathological alterations in Binswanger's diseased brains include regressive changes in the astroglia and activation of the microglia with a decrease in the oligodendroglia, which were associated with the degradation of both myelin and axonal components.

  7. Alterations of the blood-brain barrier and glial cells in white-matter lesions in cerebrovascular and Alzheimer's disease patients

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Stroke 1996-11-01 Biomarkers

    Dysfunction of the blood-brain barrier is more prominent in white-matter lesions seen in ischemic CVD than in AD and may have a role in the pathogenesis of cerebrovascular white-matter lesions.

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