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Newest in this topic

  1. Alcohol use disorder accelerates age-related cognitive decline 2026-09-23
  2. A longitudinal study of age-related traits and cognitive function: The Collaborative Amish Aging and Memory Project (CAAMP) 2026-09-20
  3. Associations of menopause hormone therapy with late-life cognition and brain health vary by formulation and APOEε4 presence 2026-09-20

Studies

1,138 studies carry this tag.

Date range

1986 to 2026

Top journals

  • Alzheimer s & Dementia 42
  • Neurology 41
  • Journal of the American Geriatrics Society 36
  • Journal of Alzheimer's disease : JAD 33
  • Nutrients 23

437 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Excessive sleepiness is predictive of cognitive decline in the elderly

    ✓ Peer-reviewed alzhub usefulness score 68 out of 100. Sleep 2012-09-01 Cognitive tests and assessment

    Study objectives To examine the association of sleep complaints reported at baseline (insomnia complaints and excessive daytime sleepiness (EDS)) and medication, with cognitive decline in community-dwelling elderly.

  2. A lower number of teeth are positively related to swallowing dysfunction, whereas denture wearing contributes to recovery of swallowing function.

  3. Glucose metabolism, gray matter structure, and memory decline in subjective memory impairment

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Neurology 2012-08-22 Brain scans and imaging

    The cross-sectional difference in 2 independent neuroimaging modalities indicates early AD pathology in SMI.

  4. Online games training aging brains: limited transfer to cognitive control functions

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Frontiers in human neuroscience 2012-08-17 Prevention trials

    The prevalence of age-related cognitive decline will increase due to graying of the global population.

  5. The impact of inflammation on cognitive function in older adults: implications for healthcare practice and research

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 2012-08-01 Prevention and risk

    Accumulating evidence suggests that levels of inflammation, an immune response, increase with age throughout the body and the brain.

  6. Postural stability and history of falls in cognitively able older adults: the Canton Ticino study

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Gait & posture 2012-07-24 Clinical safety

    Falls are common events in the elderly and represent the main risk factor for fractures and other injuries.

  7. Yogic meditation reverses NF-κB and IRF-related transcriptome dynamics in leukocytes of family dementia caregivers in a randomized controlled trial

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Psychoneuroendocrinology 2012-07-15 Caregiving

    In response to KKM treatment, 68 genes were found to be differentially expressed (19 up-regulated, 49 down-regulated) after adjusting for potentially confounded differences in sex, illness burden, and BMI.

  8. Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. Frontiers in neuroendocrinology 2012-07-11 Brain scans and imaging

    Increasingly vitamin D deficiency is being associated with a number of psychiatric conditions.

  9. Dietary patterns: a novel approach to examine the link between nutrition and cognitive function in older individuals

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Nutrition research reviews 2012-07-04 Prevention trials

    Cognitive decline may lead to dementia whose most frequent cause is Alzheimer's disease (AD).

  10. Fruit, vegetables and prevention of cognitive decline or dementia: a systematic review of cohort studies

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. The journal of nutrition, health & aging 2012-07-01 Prevention and risk

    Nine studies with a total of 44,004 participants met the inclusion criteria.

  11. P3‐314: Pictorial education of safe medication for the elderly with cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 27 out of 100. Alzheimer s & Dementia 2012-07-01 Health systems and care delivery

    Medication-related health problems in the Korean elderly have been increasing very rapidly in Korea with the population of the aged increased.

  12. The Mediterranean diet is not related to cognitive change in a large prospective investigation: the PATH Through Life study

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2012-07-01 Prevention trials

    In this large longitudinal investigation of generally healthy individuals Mediterranean diet was not found to be protective of cognitive decline.

  13. Executive function and falls in older adults: new findings from a five-year prospective study link fall risk to cognition

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. PloS one 2012-06-29 Risk factors

    Survival analyses indicated that subjects with the lowest EF scores were more likely to fall sooner and more likely to experience multiple falls during the 66 months of follow-up (p Conclusions/significance These findings demonstrate that among community-living older adults, the risk of future falls was predicted by performance on EF and attention tests conducted 5 years earlier.

  14. Mediterranean diet and cognitive decline in women with cardiovascular disease or risk factors

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Journal of the Academy of Nutrition and Dietetics 2012-06-01 Prevention trials

    In women at higher risk of cognitive decline due to vascular disease or risk factors, adherence to a Mediterranean-style diet was not associated with subsequent 5-year cognitive change.

  15. A 1-year randomized controlled trial comparing mind body exercise (Tai Chi) with stretching and toning exercise on cognitive function in older Chinese adults at risk of cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Journal of the American Medical Directors Association 2012-05-11 Prevention and risk

    Regular exercise, especially mind-body exercise with integrated cognitive and motor coordination, may help with preservation of global ability in elders at risk of cognitive decline; however, logistics to promote long-term practice and optimize adherence needs to be revisited.

  16. Sports concussions and aging: a neuroimaging investigation

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Cerebral cortex (New York, N.Y. : 1991) 2012-05-10 Hippocampus size on brain scans

    Recent epidemiological and experimental studies suggest a link between cognitive decline in late adulthood and sports concussions sustained in early adulthood.

  17. Indicators of Childhood Quality of Education in Relation to Cognitive Function in Older Adulthood

    ✓ Peer-reviewed alzhub usefulness score 49 out of 100. The Journals of Gerontology Series A 2012-04-30 Risk factors

    Higher student-teacher ratio was associated with worse cognitive function and greater school year length was associated with better cognitive function.

  18. Effectiveness of cognitive training in Chinese older people with subjective cognitive complaints: a randomized placebo-controlled trial

    ✓ Peer-reviewed alzhub usefulness score 74 out of 100. International journal of geriatric psychiatry 2012-04-23 Prevention trials

    Cognitive training was effective in enhancing the overall cognitive functioning of less educated older adults with subjective memory complaints.

  19. Positive effects of computer-based cognitive training in adults with mild cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Neuropsychologia 2012-04-21 Prevention trials

    Considering the high risk for individuals with amnestic Mild Cognitive Impairment (A-MCI) to progress towards Alzheimer's disease (AD), we investigated the efficacy of a non-pharmacological intervention, that is, cognitive training that could reduce cognitive difficulties and delay the cognitive decline.

  20. Total daily physical activity and the risk of AD and cognitive decline in older adults

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Neurology 2012-04-18 Genetics

    A higher level of total daily physical activity is associated with a reduced risk of AD.

  21. A berry thought-provoking idea: the potential role of plant polyphenols in the treatment of age-related cognitive disorders

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The British journal of nutrition 2012-04-05 Prevention trials

    Today, tens of millions of elderly individuals worldwide suffer from dementia.

  22. Disturbed sleep patterns in elders with mild cognitive impairment: the role of memory decline and ApoE ε4 genotype

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Current Alzheimer research 2012-03-01 Genetics

    Sleep disturbances are prevalent in patients with Alzheimer' disease (AD), being one of the most troubling symptoms during the progression of disease.

  23. Increased risk of cognitive and functional decline in patients with atrial fibrillation: results of the ONTARGET and TRANSCEND studies

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2012-02-27 Cognitive tests and assessment

    The role of atrial fibrillation in cognitive impairment and dementia, independent of stroke, is uncertain.

  24. The role of cognitive impairment in fall risk among older adults: a systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Age and ageing 2012-02-27 Getting a diagnosis

    Our objective was to evaluate the epidemiological evidence linking cognitive impairment and fall risk.

  25. Performance on the shopping task significantly differentiated patients and healthy controls for several variables and, in particular, for total time.

  26. Cognitive stimulation to improve cognitive functioning in people with dementia

    ✓ Peer-reviewed alzhub usefulness score 75 out of 100. The Cochrane database of systematic reviews 2012-02-15 Caregiving

    RO emphasised the engagement of nursing assistants in a hopeful, therapeutic process but became associated with a rigid, confrontational approach to people with dementia, leading to its use becoming less and less common.

  27. Effects of ω-3 fatty acids on cognitive performance: a meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Neurobiology of aging 2012-02-03 Cognitive tests and assessment

    Higher intake of omega-3 fatty acids (n-3 FAs) is associated with a reduced risk of Alzheimer's disease (AD) and milder forms of cognitive impairment (e.g. cognitive impairment no dementia [CIND]); however, findings from interventional trials are inconsistent.

  28. Exergaming and older adult cognition: a cluster randomized clinical trial

    ✓ Peer-reviewed alzhub usefulness score 70 out of 100. American journal of preventive medicine 2012-02-01 Prevention and risk

    Cybercycling older adults achieved better cognitive function than traditional exercisers, for the same effort, suggesting that simultaneous cognitive and physical exercise has greater potential for preventing cognitive decline.

  29. Changes in brain volume and cognition in a randomized trial of exercise and social interaction in a community-based sample of non-demented Chinese elders

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Journal of Alzheimer's disease : JAD 2012-01-01 Prevention and risk

    Physical exercise has been shown to increase brain volume and improve cognition in randomized trials of non-demented elderly.

  30. Polyphenol-rich foods in the Mediterranean diet are associated with better cognitive function in elderly subjects at high cardiovascular risk

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Journal of Alzheimer's disease : JAD 2012-01-01 Prevention trials

    Brain oxidative processes play a major role in age-related cognitive decline, thus consumption of antioxidant-rich foods might help preserve cognition.

  31. Chronic kidney disease, cognitive decline, and incident dementia: the 3C Study

    ✓ Peer-reviewed alzhub usefulness score 65 out of 100. Neurology 2011-11-23 Cognitive tests and assessment

    This study is based on a population-based cohort of 7,839 subjects over 65 years with 7 years of follow-up.

  32. The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort

    ✓ Peer-reviewed alzhub usefulness score 51 out of 100. The American journal of clinical nutrition 2011-11-09 Brain scans and imaging

    Loss of cholinergic neurons is associated with impaired cognitive function, particularly memory loss and Alzheimer disease (AD).

  33. Longitudinal structure-function correlates in elderly reveal MTL dysfunction with cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Cerebral cortex (New York, N.Y. : 1991) 2011-11-07 Hippocampus size on brain scans

    By integrating behavioral measures and imaging data, previous investigations have explored the relationship between biological markers of aging and cognitive functions.

  34. Multistrategic memory training with the metamemory concept in healthy older adults

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Psychiatry investigation 2011-11-03 Prevention trials

    This study shows that multistrategic memory training with the metamemory concept may improve memory ability and other cognitive functions which are not trained and that these improvements may be achieved by pure cognitive training effects.

  35. Most older patients surviving AMI have measurable CIND.

  36. Hearing loss and cognition in the Baltimore Longitudinal Study of Aging

    ✓ Peer-reviewed alzhub usefulness score 61 out of 100. Neuropsychology 2011-11-01 How common it is

    Hearing loss is independently associated with lower scores on tests of memory and executive function.

  37. Late-life social activity and cognitive decline in old age

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. Journal of the International Neuropsychological Society : JINS 2011-11-01 Brain tissue and pathology

    We examined the association of social activity with cognitive decline in 1138 persons without dementia at baseline with a mean age of 79.6 (SD = 7.5) who were followed for up to 12 years (mean = 5.2; SD = 2.8).

  38. Video-telemedicine in a memory disorders clinic: evaluation and management of rural elders with cognitive impairment

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Telemedicine journal and e-health : the official journal of the American Telemedicine Association 2011-10-24 Disparities

    VTM is emerging as an effective way to provide consultation and care to rural residents who may not have access to specialty services and can be integrated into current clinical settings.

  39. Slower gait, slower information processing and smaller prefrontal area in older adults

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Age and ageing 2011-09-28 Vascular contributions

    We conclude that smaller PFAv may contribute to slower gait through slower information processing.

  40. Cognitive and memory training in adults at risk of dementia: a systematic review

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. BMC geriatrics 2011-09-25 Mild cognitive impairment

    Previous conclusions of a lack of efficacy for cognitive training in MCI may have been influenced by not clearly defining the intervention.

  41. Depressive symptoms may increase the risk of progressing from mild cognitive impairment (MCI) to dementia.

  42. Advanced glycation end product level, diabetes, and accelerated cognitive aging

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Neurology 2011-09-07 Disease mechanisms

    High peripheral AGE level is associated with greater cognitive decline in older adults with and without diabetes.

  43. Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. Mayo Clinic proceedings 2011-09-01 Prevention and risk

    A rapidly growing literature strongly suggests that exercise, specifically aerobic exercise, may attenuate cognitive impairment and reduce dementia risk.

  44. Relation of left ventricular ejection fraction to cognitive aging (from the Framingham Heart Study)

    ✓ Peer-reviewed alzhub usefulness score 54 out of 100. The American journal of cardiology 2011-08-30 Brain scans and imaging

    Heart failure is a risk factor for Alzheimer's disease and cerebrovascular disease.

  45. Ecology of the aging human brain

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Archives of neurology 2011-08-01 Caregiving

    These data show an individually varying complex convergence of subclinical diseases in the brain of older CN adults.

  46. Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial

    ✓ Peer-reviewed alzhub usefulness score 69 out of 100. International journal of geriatric psychiatry 2011-07-21 Risk factors

    The mean plasma total homocysteine was 30% lower in those treated with B vitamins relative to placebo.

  47. Is high homocysteine level a risk factor for cognitive decline in elderly? A systematic review, meta-analysis, and meta-regression

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2011-07-01 Treatments

    Individuals with AD and VaD have higher Hct levels than controls; however, a causal relationship between high-Hct level and risk of developing dementia is not supported.

  48. Longitudinal change of biomarkers in cognitive decline

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. Archives of neurology 2011-06-13 Hippocampus size on brain scans

    Trajectories of Aβ42 level in CSF, FDG uptake, and hippocampal volume vary across different cognitive stages.

  49. New insights: dose-response relationship between psychotropic drugs and falls: a study in nursing home residents with dementia

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of clinical pharmacology 2011-05-31 Clinical safety

    The contribution of specific psychotropic drugs to fall risk in patients with dementia has not been quantified precisely until now.

  50. Good levels of participation, adherence, and retention appear to be achievable for participants through age 85 years.

From across this tag

8 of the 1,130 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 8. The same 8 appear here every time.

All topic tags with their study counts