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clinical-utility
8 studies tagged clinical-utility, dated 2018-03-20 to 2026-08-28. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Real-world long-term continuation of lecanemab therapy and the clinical utility of phosphorylated tau 181 2026-08-28
- Clinical utility of plasma p-tau217 in identifying abnormal brain amyloid burden in an Asian cohort with high prevalence of concomitant cerebrovascular disease 2025-01-14
- Clinical Utility of an Alzheimer's Disease Blood Test Among Cognitively Impaired Patients: Results from the Quality Improvement PrecivityAD2 (QUIP II) Clinician Survey Study 2025-01-13
Studies
8 studies carry this tag.
Date range
2018 to 2026
Top journals
- Alzheimer's & dementia (Amsterdam, Netherlands) 1
- Alzheimer's & dementia : the journal of the Alzheimer's Association 1
- Alzheimer's research & therapy 1
- Annals of clinical and translational neurology 1
- Diagnostics (Basel, Switzerland) 1
8 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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This real-world study evaluated the long-term feasibility of lecanemab treatment in 117 patients with early Alzheimer's disease at Kanazawa University Hospital.
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Risk stratification for PET Aβ+ based on a plasma p-tau217 assay demonstrated potential diagnostic and prognostic utility in an Asian cohort with concomitant CeVD.
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Patients had a median age of 74, 53% were female, and 28% were traditionally under-represented in Black, Hispanic, and Asian groups.
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High-throughput plasma Aβ42/40 LC-MS/MS assays can help identify patients with low likelihood of AD pathology, which can reduce PET evaluations, allowing for cost savings.
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The study team reported a significant change in diagnoses and patient medication when tau PET was added to an already extensive diagnostic workup that included cerebrospinal fluid AD biomarkers.
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ABtest-MS accurately identified brain amyloid deposition in a population of CU individuals, supporting its implementation in AD secondary prevention trials to reduce recruitment time and costs.
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CSF biomarkers measured with the LUMIPULSE system showed good agreement with amyloid PET imaging.
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There were significant global differences in Aβ1-42, T-tau, T-tau/Aβ1-42 ratio, P-tau-181, NFL, AβX-42, AβX-42/X-40 ratio, APPα, and APPβ between groups.