chromosome

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

1. 43/100

   Immune cells lacking Y chromosome show dysregulation of autosomal gene expression

   ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Cellular and molecular life sciences : CMLS · 2021-04-10 · Genetics

   Epidemiological investigations show that mosaic loss of chromosome Y (LOY) in leukocytes is associated with earlier mortality and morbidity from many diseases in men.

   • Genetics
   • Brain Biology
2. 38/100

   Mosaic loss of human Y chromosome: what, how and why

   ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Human genetics · 2020-02-04 · Genetics

   Y chromosome (ChrY), the male-specific sex chromosome, has been considered as a genetic wasteland.

   • Genetics
3. 57/100

   Longitudinal changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men varies profoundly between individuals

   ✓ Peer-reviewed alzhub usefulness score 57 out of 100. European journal of human genetics : EJHG · 2019-10-25 · Genetics

   Mosaic loss of chromosome Y (LOY) is the most common somatic genetic aberration and is associated with increased risk for all-cause mortality, various forms of cancer and Alzheimer's disease, as well as other common human diseases.

   • Genetics
4. 47/100

   Y chromosome mosaicism is associated with age-related macular degeneration

   ✓ Peer-reviewed alzhub usefulness score 47 out of 100. European journal of human genetics : EJHG · 2018-08-29 · Genetics

   Age-related macular degeneration (AMD) is the leading cause of blindness in industrialised countries, and thereby a major individual but also a socio-economic burden.

   • Genetics
5. 40/100

   Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13.2-21.3

   ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Brain : a journal of neurology · 2006-02-22 · Risk genes beyond APOE

   Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are both relentlessly progressive and ultimately fatal neurological disorders.

   • Genetics
   • Other Dementias
6. 41/100

   Susceptibility locus for Alzheimer's disease on chromosome 10

   ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Science (New York, N.Y.) · 2000-12-01 · Genetics

   The apolipoprotein E (APOE) gene is the only genetic risk factor that has so far been linked to risk for late-onset Alzheimer's disease (LOAD).

   • Genetics
7. 41/100

   Mapping of a gene for Parkinson's disease to chromosome 4q21-q23

   ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Science (New York, N.Y.) · 1996-11-01 · Risk genes beyond APOE

   Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease, affecting approximately 1 percent of the population over age 50.

   • Genetics
   • Other Dementias
8. 40/100

   Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14

   ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Nature genetics · 1992-12-01 · Risk genes beyond APOE

   Familial Alzheimer's disease (FAD) has been shown to be genetically heterogeneous, with a very small proportion of early onset pedigrees being associated with mutations in the amyloid precursor protein (APP) gene on chromosome 21, and some late onset pedigrees showing associations with markers on chromosome 19.

   • Genetics

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