The National Alzheimer's Coordinating Center (NACC) Database: The Uniform Data Set

Topic: Amyloid, tau and blood-test diagnosis

The National Alzheimer's Coordinating Center (NACC) is responsible for developing and maintaining a database of participant information collected from the 29 Alzheimer's Disease Centers (ADCs) funded by the National Institute on Aging (NIA). The NIA appointed the ADC Clinical Task Force to determine and define an expanded, standardized clinical data set, called the Uniform Data Set (UDS). The goal of the UDS is to provide ADC researchers a standard set of assessment procedures, collected longitudinally, to better characterize ADC participants with mild Alzheimer disease and mild cognitive impairment in comparison with nondemented controls. NACC implemented the UDS (September 2005) by developing data collection forms for initial and follow-up visits based on Clinical Task Force definitions, a relational database, and a data submission system accessible by all ADCs. The NIA requires ADCs to submit UDS data to NACC for all their Clinical Core participants. Thus, the NACC web site (https://www.alz.washington.edu) was enhanced to provide efficient and secure access data submission and retrieval systems.

Why it matters

Describes the Uniform Data Set, a standard set of assessments collected over time from participants at the 29 Alzheimer's Disease Centers funded by the National Institute on Aging. It is meant to help compare people with mild Alzheimer's and mild cognitive impairment with people without dementia.

Read the original

• DOI: 10.1097/wad.0b013e318142774e
• PubMed: 17804958
• Original source →

May need a subscription OpenAlex found no free copy of the full text (checked 6 Feb 1020), so the publisher may charge for it. The PubMed abstract is free.

@article{beekly2007-17804958,
  author  = {Beekly, Duane L. and Ramos, Erin M. and Lee, William W. and Deitrich, Woodrow D. and Jacka, Mary E. and Wu, Joylee and Hubbard, Janene L. and Koepsell, Thomas D. and Morris, John C. and Kukull, Walter A.},
  title   = {{The National Alzheimer's Coordinating Center (NACC) Database: The Uniform Data Set}},
  journal = {Alzheimer Disease \& Associated Disorders},
  year    = {2007},
  doi     = {10.1097/wad.0b013e318142774e},
  pmid    = {17804958},
  url     = {https://doi.org/10.1097/wad.0b013e318142774e}
}

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