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52/100

✓ Peer-reviewed alzhub usefulness score 52 out of 100. Treatments

Topic: Drug trials: efficacy and safety

Overall, 304 patients receiving cholinesterase inhibitors/memantine also received anticholinergics. Of these patients, 64.1% were given high-potency anticholinergic medications, and 35.9% received medium-potency medications. Indications for the use of anticholinergic medication were urological (17.8%), gastrointestinal excluding nausea (32.6%), nausea (10.2%), psychiatric (7.9%), and other (31.6%). Asian patients received the combination of cholinesterase inhibitors/memantine and anticholinergics less frequently than Native Hawaiian or Caucasian patients (8.4% vs 12.2% and 13.3%, respectively; χ2 = 16.04, degrees of freedom = 2, P < 0.0003). Simultaneous prescribing of cholinesterase inhibitors, memantine, and anticholinergic medications was significantly less common than in previous studies, with some ethnic variability. The less frequent occurrence of concurrent medications in the Asian population may be because of variations in the rate of indications or in tolerability for anticholinergic medications among the population.

Key findings

Overall, 304 patients receiving cholinesterase inhibitors/memantine also received anticholinergics.
Of these patients, 64.1% were given high-potency anticholinergic medications, and 35.9% received medium-potency medications.
Indications for the use of anticholinergic medication were urological (17.8%), gastrointestinal excluding nausea (32.6%), nausea (10.2%), psychiatric (7.9%), and other (31.6%).
Asian patients received the combination of cholinesterase inhibitors/memantine and anticholinergics less frequently than Native Hawaiian or Caucasian patients (8.4% vs 12.2% and 13.3%, respectively; χ2 = 16.04, degrees of freedom = 2, P < 0.0003).
Simultaneous prescribing of cholinesterase inhibitors, memantine, and anticholinergic medications was significantly less common than in previous studies, with some ethnic variability.

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Study details

Participants304
Effect size64.1%; 35.9%; 17.8%
Evidence strengthLow

How this study scored 52/100

Published in a peer-reviewed journal. Scored zero for study design and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multi-centre collaboration and free to read, so those were left out: it earned 29 of the 56 points we could judge it on, which is 52 out of 100.

Component	Points	Why
Journal tier	7 / 10	Tier 3 — peer-reviewed journal (Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society)
Journal's citation record	— / 4	No journal record from OpenAlex — left out of this score
Study design	0 / 12	No study design recorded — scores zero, not guessed (not stated in the record — scored 0)
Strength of evidence	1 / 5	Rated “low” in our summary
Peer-review validation	10 / 10	Peer-reviewed. Published as an article in a named peer-reviewed journal.
How recent	2 / 5	2017 — within 10 year(s) of the newest study here
Sample size	2 / 4	304 participants
Effect reported	2 / 3	Effect reported as a number, without an interval or test
Studied in people	3 / 3	Studied in people (participant count stated)
Randomised / blinded	0 / 2	No randomisation or blinding stated — scores zero (not stated in the record — scored 0)
Times cited	— / 7	No citation count (not found in OpenAlex) — left out of this score
Citations per year	— / 5	No citation count or no year — left out of this score
Impact for its field and year	— / 6	No field-weighted citation impact (OpenAlex has none yet) — left out of this score
Cited by studies here	— / 6	Not yet checked against this library's citation graph — left out of this score
Still being cited	— / 4	No yearly citation counts — left out of this score
Senior author's track record	— / 4	Senior author's record not available — left out of this score
Institution's track record	— / 3	No institution listed in OpenAlex — left out of this score
Multi-centre collaboration	— / 3	Institutions not listed — left out of this score
Indexed in PubMed	2 / 2	Indexed in PubMed (PMID 28387023)
Free to read	— / 2	Access not recorded — left out of this score
Points	29 / 56	Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 29 of the 56 points we could judge it on is 52 out of 100.
Total	52 / 100	—

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Cite this study APA, Vancouver, BibTeX · download .bib or .ris

Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 7 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.

APA 7th

Schultz, B. R., Takeshita, J., Goebert, D., Takeshita, S., Lu, B. Y., Guilloux, A., et al. (2017). Simultaneous usage of dementia medications and anticholinergics among Asians and Pacific Islanders. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. https://doi.org/10.1111/psyg.12267

Vancouver

Schultz BR, Takeshita J, Goebert D, Takeshita S, Lu BY, Guilloux A, et al. Simultaneous usage of dementia medications and anticholinergics among Asians and Pacific Islanders. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. 2017. doi:10.1111/psyg.12267. PMID: 28387023.

BibTeX

@article{schultz2017-28387023,
  author  = {Schultz, Brian R and Takeshita, Junji and Goebert, Deborah and Takeshita, Steven and Lu, Brett Y and Guilloux, Alexandre and Higa, Joy},
  title   = {{Simultaneous usage of dementia medications and anticholinergics among Asians and Pacific Islanders}},
  journal = {Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society},
  year    = {2017},
  doi     = {10.1111/psyg.12267},
  pmid    = {28387023},
  url     = {https://doi.org/10.1111/psyg.12267}
}

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