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Perspectives in dementia risk reduction – food for thought
Jill Rasmussen. Neurodegenerative Disease Management, 2026-05-11
Topic: Risk, prevention and care in population studies
Diet and specific nutritional factors, alone and in combination with other lifestyle approaches, have an important role in decreasing the risk for dementia. Protective factors for dementia risk reduction are important in early as well as late adult life, since pathological processes underlying dementia begin years before clinical symptoms appear. Decreased levels of nutrients, such as B vitamins and omega-3 fatty acids, exacerbate pathological processes contributing to cognitive impairment. Initial work using specific diets, including the MIND diet (which combines elements of the Mediterranean and DASH diets), has shown potential to reduce the risk of cognitive decline and/or improve cognitive function, but further research is required. Although the benefits of single-agent nutrient supplementation are unclear, the LipiDiDiet trial has indicated that multinutrient supplementation with Fortasyn Connect may have the potential to improve cognitive function and decrease disease progression in individuals with prodromal Alzheimer's disease. The worldwide FINGER studies are assessing the potential benefits of multidomain lifestyle-based interventions in the prevention of cognitive decline, including dietary interventions. Evidence for the importance of nutrition in combination with lifestyle approaches in maintaining a healthy brain indicates that public health policy must consider nutrition and diet when targeting dementia risk reduction and healthy aging.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Rasmussen, J. (2026). Perspectives in dementia risk reduction – food for thought. Neurodegenerative Disease Management. https://doi.org/10.1080/17582024.2026.2669599
Vancouver
Rasmussen J. Perspectives in dementia risk reduction – food for thought. Neurodegenerative Disease Management. 2026. doi:10.1080/17582024.2026.2669599. PMID: 42112907.
BibTeX
@article{rasmussen2026-42112907,
author = {Rasmussen, Jill},
title = {{Perspectives in dementia risk reduction – food for thought}},
journal = {Neurodegenerative Disease Management},
year = {2026},
doi = {10.1080/17582024.2026.2669599},
pmid = {42112907},
url = {https://doi.org/10.1080/17582024.2026.2669599}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
Key findings
- Although the benefits of single-agent nutrient supplementation are unclear, the LipiDiDiet trial has indicated that multinutrient supplementation with Fortasyn Connect may have the potential to improve cognitive function and decrease disease progression in individuals with prodromal Alzheimer's disease.
- Evidence for the importance of nutrition in combination with lifestyle approaches in maintaining a healthy brain indicates that public health policy must consider nutrition and diet when targeting dementia risk reduction and healthy aging.
Why it matters
This review says diet and nutrition may help lower dementia risk, but it notes that more research is needed and that the benefits of single-nutrient supplements are unclear. It reports that the LipiDiDiet trial suggested a multinutrient supplement may improve cognitive function and slow progression in people with prodromal Alzheimer's disease.
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Study details
- Evidence strengthLow
How this study scored 33/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it. We have no data on institution's track record, so that was left out: it earned 32 of the 97 points we could judge it on, which is 33 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Neurodegenerative Disease Management) |
| Journal's citation record | 0 / 4 | Neurodegenerative Disease Management: journal h-index 47 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 5 / 5 | 2026 — within 1 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 1 / 7 | Cited 1 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.5 citations a year over 2 year(s) since 2026 |
| Impact for its field and year | 3 / 6 | Cited 4.7× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 1 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 1 / 4 | Last-listed author Jill Rasmussen: h-index 10 (OpenAlex, whole career) |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | 0 / 3 | OpenAlex lists 0 institution(s) in 0 countries — scores zero (affiliation lists can be incomplete) |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 42112907) |
| Free to read | 2 / 2 | Free to read |
| Points | 32 / 97 | Scored on 19 of 20 parts. We have no data for the rest, so they are left out: 32 of the 97 points we could judge it on is 33 out of 100. |
| Total | 33 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.1080/17582024.2026.2669599
- PubMed: 42112907
- Original source →
- Free full text: Neurodegenerative Disease Management →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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