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Medical comorbidity in schizophrenia
Jeste DV, Gladsjo JA, Lindamer LA, Lacro JP.. Schizophrenia bulletin, 1996-01-01
Topic: Risk, prevention and care in population studies
The extent and consequences of medical comorbidity in patients with schizophrenia are generally underrecognized. Patients with comorbid conditions are usually excluded from research studies, although they probably represent the majority of individuals with schizophrenia. Elderly patients are especially likely to have comorbid disorders.
Key findings
- Patients with comorbid conditions are usually excluded from research studies, although they probably represent the majority of individuals with schizophrenia.
- Elderly patients are especially likely to have comorbid disorders.
- In this article, we review selected literature on medical comorbidity in schizophrenia, including physical illnesses, substance use, cognitive impairment, sensory deficits, and iatrogenic comorbidity.
- Data from the University of California, San Diego Clinical Research Center on late-life psychosis are also presented.
Why it matters
This review discusses medical comorbidity in schizophrenia, including physical illnesses, substance use, cognitive impairment, sensory deficits and iatrogenic comorbidity. It concerns schizophrenia and does not show any treatment, cure or prevention for Alzheimer's disease.
Study details
- Evidence strengthLow
How this study scored 42/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, effect reported, studied in people and randomised / blinded because the record does not state it.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Schizophrenia bulletin) |
| Journal's citation record | 3 / 4 | Schizophrenia Bulletin: journal h-index 298 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 1996 — older than 20 years, still counted |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 6 / 7 | Cited 626 times (OpenAlex, 2026-10-10) |
| Citations per year | 3 / 5 | 19.6 citations a year over 32 year(s) since 1996 |
| Impact for its field and year | 3 / 6 | Cited 6.6× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 1 / 4 | Cited 14 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | 2 / 4 | Last-listed author Jonathan P. Lacro: h-index 23 (OpenAlex, whole career) |
| Institution's track record | 2 / 3 | University of California San Diego: institution h-index 1,852 (OpenAlex) |
| Multi-centre collaboration | 1 / 3 | OpenAlex lists 2 institution(s) in 1 country |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 8873293) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Total | 42 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
May need a subscription OpenAlex found no free copy of the full text (checked 6 Feb 1020), so the publisher may charge for it. The PubMed abstract is free.
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
APA 7th
Jeste, D. V., Gladsjo, J. A., Lindamer, L. A., & Lacro, J. P. (1996). Medical comorbidity in schizophrenia. Schizophrenia bulletin. https://doi.org/10.1093/schbul/22.3.413
Vancouver
Jeste DV, Gladsjo JA, Lindamer LA, Lacro JP. Medical comorbidity in schizophrenia. Schizophrenia bulletin. 1996. doi:10.1093/schbul/22.3.413. PMID: 8873293.
BibTeX
@article{jeste1996-8873293,
author = {Jeste, D. V. and Gladsjo, J. A. and Lindamer, L. A. and Lacro, J. P.},
title = {{Medical comorbidity in schizophrenia}},
journal = {Schizophrenia bulletin},
year = {1996},
doi = {10.1093/schbul/22.3.413},
pmid = {8873293},
url = {https://doi.org/10.1093/schbul/22.3.413}
}
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