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AI-Driven Alzheimer’s Detection Performance Analysis of Pretrained CNN Models on MRI Data
Varun Patel. International Journal for Research in Applied Science and Engineering Technology, 2025-04-08
Topic: Amyloid, tau and blood-test diagnosis
Alzheimer's disease (AD) is a memory and cognitive function neurodegenerative disease. Early diagnosis is important for appropriate treatment, but conventional diagnosing techniques are not very effective. In this paper, automatic detection of Alzheimer's disease from MRI scans using deep learning techniques is discussed. We trained and compared six pre-trained Convolutional Neural Network (CNN) models—VGG19, ResNet101, EfficientNetB3, MobileNetV2, InceptionV3, and DenseNet121—to differentiate MRI scans as Alzheimer and Non-Alzheimer. In experiments, InceptionV3 is the optimal model for classification of Alzheimer's disease and all others are inferior with an accuracy of 99.2%. Confusion matrices, classification reports, and accuracy metrics were utilized to test performance. We also created a web-based real-time MRI classification tool with a user-friendly interface for clinicians. This work showcases the potential of deep learning in medical imaging and the detection of early disease, and opens the door to AI-augmented improvement in Alzheimer's diagnosis
Cite this study APA, Vancouver, BibTeX · download .bib or .ris
APA 7th
Patel, V. (2025). AI-Driven Alzheimer’s Detection Performance Analysis of Pretrained CNN Models on MRI Data. International Journal for Research in Applied Science and Engineering Technology. https://doi.org/10.22214/ijraset.2025.68354
Vancouver
Patel V. AI-Driven Alzheimer’s Detection Performance Analysis of Pretrained CNN Models on MRI Data. International Journal for Research in Applied Science and Engineering Technology. 2025. doi:10.22214/ijraset.2025.68354.
BibTeX
@article{patel2025-90032e72,
author = {Patel, Varun},
title = {{AI-Driven Alzheimer’s Detection Performance Analysis of Pretrained CNN Models on MRI Data}},
journal = {International Journal for Research in Applied Science and Engineering Technology},
year = {2025},
doi = {10.22214/ijraset.2025.68354},
url = {https://doi.org/10.22214/ijraset.2025.68354}
}
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. Check the citation against the original before you use it.
Key findings
- We trained and compared six pre-trained Convolutional Neural Network (CNN) models—VGG19, ResNet101, EfficientNetB3, MobileNetV2, InceptionV3, and DenseNet121—to differentiate MRI scans as Alzheimer and Non-Alzheimer.
- In experiments, InceptionV3 is the optimal model for classification of Alzheimer's disease and all others are inferior with an accuracy of 99.2%.
- Confusion matrices, classification reports, and accuracy metrics were utilized to test performance.
- We also created a web-based real-time MRI classification tool with a user-friendly interface for clinicians.
- This work showcases the potential of deep learning in medical imaging and the detection of early disease, and opens the door to AI-augmented improvement in Alzheimer's diagnosis
Why it matters
This study compared six pre-trained deep learning models for detecting Alzheimer's disease from MRI scans, with one model reaching 99.2% accuracy, and also created a web tool for clinicians. It is a detection method only and does not test any treatment, cure, or prevention.
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Study details
- Effect size99.2%
- Evidence strengthLow
How this study scored 31/100
Published in a peer-reviewed journal. Scored zero for study design, sample size, studied in people and randomised / blinded because the record does not state it. We have no data on senior author's track record and institution's track record, so those were left out: it earned 29 of the 93 points we could judge it on, which is 31 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (International Journal for Research in Applied Science and Engineering Technology) |
| Journal's citation record | 0 / 4 | International Journal for Research in Applied Science and Engineering Technology: journal h-index 42 (OpenAlex, 2026-10-29) |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 4 / 5 | 2025 — within 3 year(s) of the newest study here |
| Sample size | 0 / 4 | Participant count not stated — scores zero (not stated in the record — scored 0) |
| Effect reported | 2 / 3 | Effect reported as a number, without an interval or test |
| Studied in people | 0 / 3 | Not stated whether this was studied in people — scores zero (not stated in the record — scored 0) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | 1 / 7 | Cited 1 times (OpenAlex, 2026-10-10) |
| Citations per year | 0 / 5 | 0.3 citations a year over 3 year(s) since 2025 |
| Impact for its field and year | 1 / 6 | Cited 0.6× the average for papers of its field and year (OpenAlex FWCI) |
| Cited by studies here | 0 / 6 | No other study in this library cites it |
| Still being cited | 0 / 4 | Cited 1 times in 2024–2026 (2026 still in progress; OpenAlex) |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | 0 / 3 | OpenAlex lists 0 institution(s) in 0 countries — scores zero (affiliation lists can be incomplete) |
| Indexed in PubMed | 1 / 2 | Not in PubMed, but has a DOI |
| Free to read | 2 / 2 | Free to read |
| Points | 29 / 93 | Scored on 18 of 20 parts. We have no data for the rest, so they are left out: 29 of the 93 points we could judge it on is 31 out of 100. |
| Total | 31 / 100 | — |
What each of these 20 components measures, and what this score is not →
Read the original
- DOI: 10.22214/ijraset.2025.68354
- Original source →
- Free full text: International Journal for Research in Applied Science and Engineering Technology →
Full text: free to read — OpenAlex lists this copy as free to read: the link above (checked 6 Feb 1020).
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