27,380 Alzheimer's and dementia studies in plain English, each scored out of 100.
Neurodegenerative proteinopathies are defined by distinct proteins whose folding, trafficking and clearance depend on shared proteostasis machinery. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Across cellular and animal Aβ injury models, BML-288 attenuated oxidative and inflammatory disturbances, modulated apoptosis-related protein expression, and improved cognitive outcomes. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Apigenin is an abundant, bioactive phytochemical with reported therapeutic potential and neuroprotective effects in a variety of age-related disease models. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Alzheimer's disease (AD) is a neurologic condition that is categorized by a progressive loss of neurons with time. 1 key finding →
Evidence: low
Full summary, score breakdown and related studies → Original source
Environmental microplastics and nanoplastics (MNPs) are emerging contaminants that accumulate in human tissues, including the brain, yet their mechanistic impact on the nervous system remains poorly understood. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Alzheimer’s disease (AD) is characterised by aberrant amyloid beta and tau aggregation, neuroinflammation, demyelination and neurodegeneration, which have been linked to changes in cell-specific gene expression signatures. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Forty-eight studies from ten Southeast Asian countries were reviewed. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
People from UK South Asian communities experience barriers to accessing dementia care. 1 key finding →
Participants: 14 Evidence: low
Full summary, score breakdown and related studies → Original source
Although dementias primarily affect memory, they also disrupt our closest social relationships, resulting in elevated caregiver burden and worse patient outcomes. 2 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
GRACE has demonstrated clinical and cost-effectiveness in trial settings, providing a strong foundation for wider implementation. 2 key findings →
Participants: 19 Evidence: low
Full summary, score breakdown and related studies → Original source
The conventional model (M2) concordance index (C-index) was 0.680, but fell to 0.649 when missingness indicators were removed. 4 key findings →
Participants: 1,643 Evidence: low
Full summary, score breakdown and related studies → Original source
M2 C-index 0.682, M3 0.692, M4 0.687. Adding the dyadic mean yielded an estimated ΔC of 0.010 (95% CI -0.003 to 0.024). 4 key findings →
Participants: 1,762 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Three interrelated themes emerged: relational foundations of caregiving, multidimensional struggles of caregiving, and benefits of caregiving. 5 key findings →
Evidence: moderate
Full summary, score breakdown and related studies → Original source
Our results showed that caregiving burden was negatively associated with the sense of ability.. 3 key findings →
Design: cross-sectional Participants: 355 Evidence: low
Full summary, score breakdown and related studies → Original source
This interdisciplinary, prototype-centered AI education program was associated with significant short-term improvements in students’ perceived AI knowledge, digital mental health readiness, interdisciplinary collaboration, innovation capacity, STEM career readiness, and solution-design ability. 4 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Caregiver narratives were predominantly negative (89.3% of posts; mean valence - 0.46), with interpretable structure. 2 key findings →
Design: longitudinal study Participants: 7,198 Evidence: moderate
Full summary, score breakdown and related studies → Original source
The culturally adapted CSP enhanced self-efficacy among Chinese Australian carers of people with dementia, but not carer burden, quality of life and approach to dementia care. 3 key findings →
Participants: 48 Evidence: low
Full summary, score breakdown and related studies → Original source
Four main themes emerged from the data: 1) the unseen challenges of caregiving; 2) knowledge and experiences lead to stronger self-confidence; 3) the power of peer influence on caregiving; and 4) pursuing better support for carers. 5 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Although caregivers demonstrated resilience and adaptive coping, YOD caregiving in Singapore remained constrained by limited access to visible, tailored, and age-appropriate support. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
Caregiving for older adults with dementia in Northern Ethiopia is a totalizing and demanding experience that profoundly affects caregivers’ lives. 2 key findings →
Participants: 25 Evidence: low
Full summary, score breakdown and related studies → Original source
Family physicians' empathy levels were independently associated with general, supportive, and accepting attitudes toward people with dementia, but not with exclusionary attitudes. 5 key findings →
Design: cross-sectional Participants: 412 Evidence: low
Full summary, score breakdown and related studies → Original source
Internet use for health information was significantly associated with Alzheimer’s disease diagnosis. 3 key findings →
Evidence: low
Full summary, score breakdown and related studies → Original source
The prognostic significance of psychosis in dementia differs by symptom profile. 4 key findings →
Participants: 21,108 Evidence: moderate
Full summary, score breakdown and related studies → Original source
Functional decline, as assessed by CGA, was more prominent in patients undergoing hemodialysis than in those not undergoing hemodialysis. 3 key findings →
Participants: 328 Evidence: low
Full summary, score breakdown and related studies → Original source
Recent mechanistic evidence identifies lithium deficiency as a driver of Alzheimer’s disease and related dementias (ADRD) pathogenesis. 4 key findings →
Evidence: high
Full summary, score breakdown and related studies → Original source
Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read
This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.
Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.
Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.
We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.
The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.
See the whole rubric drawn out → — four charts covering all 27,380 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.
This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 27,380 records, built mostly from automated pulls of Europe PMC (60.6% of the library) and OpenAlex (18.6%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.
1,032 records (3.8% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.
See the full, machine-readable breakdown of this library's coverage →