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Research

28,580 Alzheimer's and dementia studies in plain English, each scored out of 100.

Find studies

Showing 1,676–1,700 of 15,839 studies scoring 30–49 out of 100 (page 68 of 634) · 28,580 in the whole library · How the 0–100 score works

Download bibliography of the first 500 of these studies, in this order: BibTeX (.bib) · RIS (.ris)

Browse by subject, author or institution

Each number is how many studies that link shows, with your other filters kept.

Subjects

Authors

Names as each record prints them; the same person can appear under two spellings.

Institutions

From OpenAlex; 14,058 studies have no institution on record and are not counted here.

A note on reading research. One study is rarely the final word.

We try to note the size of a study, whether it was in humans or animals, and how early-stage the finding is. If a summary here doesn't make that clear, treat it with extra caution and check the original source.

Perceived Stress and Cognitive Decline in Different Cognitive Domains in a Cohort of Older African Americans

✓ Peer-reviewed alzhub usefulness score 47 out of 100. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2016-10-11

Research indicates that stress is linked to cognitive dysfunction. 2 key findings →

Participants: 467 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Exploring sex differences in the relationship between depressive symptoms and dementia incidence: prospective results from the PAQUID Study

✓ Peer-reviewed alzhub usefulness score 47 out of 100. Journal of the American Geriatrics Society 2003-08-01

Ninety-seven men (incidence rate: 14.4/1,000) and 183 women (Incidence rate: 19.0/1,000) developed dementia during 8 years of follow-up. 3 key findings →

Evidence: moderate

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Reducing antipsychotic drug use in nursing homes. A controlled trial of provider education

✓ Peer-reviewed alzhub usefulness score 47 out of 100. Archives of internal medicine 1993-03-01

This suggests that for many antipsychotic drug users benefits may be marginal and that programs to reduce such drug use among the 250,000 US nursing home residents receiving these drugs should have high priority. 2 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Rural-urban differences in diagnostic incidence and prevalence of Alzheimer's disease and related dementias

✓ Peer-reviewed alzhub usefulness score 47 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2021-03-04

These data suggest that older adults in rural communities may be underdiagnosed with ADRD, and/or diagnosed at later stages of dementia. 3 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Physical aggression in dementia patients and its relationship to depression

✓ Peer-reviewed alzhub usefulness score 47 out of 100. The American journal of psychiatry 1999-01-01

A substantial minority of patients with dementia exhibit physically aggressive behavior, and this aggression is strongly linked with the presence of depressive symptoms. 2 key findings →

Participants: 541 Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Endogenous sex hormone levels and risk of cognitive decline in an older biracial cohort

✓ Peer-reviewed alzhub usefulness score 47 out of 100. Neurobiology of aging 2006-11-09

Older women with low estradiol levels were more likely to experience decline in global cognitive function and verbal memory, and a similar trend was observed for verbal memory in men. 4 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Development and evaluation of a decision aid on mammography screening for women 75 years and older

✓ Peer-reviewed alzhub usefulness score 47 out of 100. JAMA internal medicine 2014-03-01

The median age of participants was 79 years, 69% (31 of 45) were of non-Hispanic white race/ethnicity, and 60% (27 of 45) had attended at least some college. 2 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

When home caregiving ends: a longitudinal study of outcomes for caregivers of relatives with dementia

✓ Peer-reviewed alzhub usefulness score 47 out of 100. Journal of the American Geriatrics Society 1995-01-01

Caregivers most frequently cite deteriorating patient conditions as the main causes of ending home care. 2 key findings →

Design: longitudinal study Evidence: moderate

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Does the Clock Drawing Test predict cognitive decline in older persons independent of the Mini-Mental State Examination? The FINE Study Group. Finland, Italy, The Netherlands Elderly

✓ Peer-reviewed alzhub usefulness score 47 out of 100. Journal of the American Geriatrics Society 1996-11-01

A preplanned analysis of data collected during the second (1991) and the third (1995) follow-up of the Italian rural cohorts of the FINE Study (Finland, Italy, the Netherlands Elderly). 1 key finding →

Participants: 247 Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Early parental death and remarriage of widowed parents as risk factors for Alzheimer disease: the Cache County study

✓ Peer-reviewed alzhub usefulness score 47 out of 100. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2011-09-01

Parental death during childhood is associated with higher prevalence of AD, with different critical periods for father's versus mother's death, with strength of these associations attenuated by remarriage of the widowed parent. 5 key findings →

Participants: 4,108 Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Parkinson's disease: a review

✓ Peer-reviewed alzhub usefulness score 47 out of 100. Frontiers in bioscience (Scholar edition) 2014-01-01

Parkinson's Disease is the second most common progressive neurodegenerative disorder affecting older American adults and is predicted to increase in prevalence as the United States population ages. 3 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

Obese-type gut microbiota induce neurobehavioral changes in the absence of obesity

✓ Peer-reviewed alzhub usefulness score 47 out of 100. Biological psychiatry 2014-07-18

These data reinforce the link between gut dysbiosis and neurologic dysfunction and suggest that dietary and/or pharmacologic manipulation of gut microbiota could attenuate the neurologic complications of obesity. 4 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Biomagnification of cyanobacterial neurotoxins and neurodegenerative disease among the Chamorro people of Guam

✓ Peer-reviewed alzhub usefulness score 47 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2003-11-01

We here report biomagnification (the increasing accumulation of bioactive, often deleterious molecules through higher trophic levels of a food chain) of the neurotoxic nonprotein amino acid beta-methylamino-l-alanine (BMAA) in the Guam ecosystem. 5 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Disease-related microglia heterogeneity in the hippocampus of Alzheimer's disease, dementia with Lewy bodies, and hippocampal sclerosis of aging

✓ Peer-reviewed alzhub usefulness score 47 out of 100. Acta neuropathologica communications 2015-05-23

We conclude that variations in morphologies among microglial cells, and cells of macrophage lineage, can help guide future work connecting neuroinflammatory mechanisms with specific neurodegenerative disease subtypes. 3 key findings →

Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

Data mining methods in the prediction of Dementia: A real-data comparison of the accuracy, sensitivity and specificity of linear discriminant analysis, logistic regression, neural networks, support vector machines, classification trees and random forests

✓ Peer-reviewed alzhub usefulness score 47 out of 100. BMC research notes 2011-08-17

These methods may be used to improve accuracy, sensitivity and specificity of Dementia predictions from neuropsychological testing. 3 key findings →

Evidence: low

Full summary, score breakdown and related studies → Original source Free full text

Classification and clinicoradiologic features of primary progressive aphasia (PPA) and apraxia of speech

✓ Peer-reviewed alzhub usefulness score 47 out of 100. Cortex; a journal devoted to the study of the nervous system and behavior 2015-05-27

The consensus criteria for the diagnosis and classification of primary progressive aphasia (PPA) have served as an important tool in studying this group of disorders. 4 key findings →

Evidence: moderate

Full summary, score breakdown and related studies → Original source Free full text

A novel multi-modal machine learning based approach for automatic classification of EEG recordings in dementia

✓ Peer-reviewed alzhub usefulness score 47 out of 100. Neural networks : the official journal of the International Neural Network Society 2019-12-14

Electroencephalographic (EEG) recordings generate an electrical map of the human brain that are useful for clinical inspection of patients and in biomedical smart Internet-of-Things (IoT) and Brain-Computer Interface (BCI) applications. 1 key finding →

Evidence: low

Full summary, score breakdown and related studies → Original source Full text may need a subscription

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Where “Free full text” comes from

Free full text links and the Full text may need a subscription label come from Unpaywall, Europe PMC and OpenAlex records of free copies, checked 10 Oct 2026. A study with neither is unknown, not paywalled. Show only studies that are free to read

How the 0–100 score works — and why some entries are capped

This is alzhub's own score. It is not an official metric, not an impact factor, and no journal, publisher or ranking body endorses it. We built it so that a reader who is not a scientist can tell a landmark trial from a conference abstract without having to already know the difference. Every point comes from one of 20 components, all of them printed on the study itself, so you can disagree with our arithmetic rather than having to trust the total.

  • Journal tier up to 10 pts
  • Journal's citation record up to 4 pts
  • Study design up to 12 pts
  • Strength of evidence up to 5 pts
  • Peer-review validation up to 10 pts
  • How recent up to 5 pts
  • Sample size up to 4 pts
  • Effect reported up to 3 pts
  • Studied in people up to 3 pts
  • Randomised / blinded up to 2 pts
  • Times cited up to 7 pts
  • Citations per year up to 5 pts
  • Impact for its field and year up to 6 pts
  • Cited by studies here up to 6 pts
  • Still being cited up to 4 pts
  • Senior author's track record up to 4 pts
  • Institution's track record up to 3 pts
  • Multi-centre collaboration up to 3 pts
  • Indexed in PubMed up to 2 pts
  • Free to read up to 2 pts

Journals are placed in ordered tiers, never given a numeric impact factor — we could not verify current impact factors from a source we control, and an invented one would be worse than none. Tier 1 is the top-tier general journals (NEJM, The Lancet, JAMA, Nature, Science, Nature Medicine); tier 2 is the leading specialty journals; tier 3 is every other peer-reviewed journal. A separate part scores how much the journal's own papers are cited, which tells the tier-3 journals apart.

Two rules we don't bend. First, we never fill in a missing value: if a record does not state a sample size or a design, that component scores zero, and if we simply have no data for a part, such as a citation count, that part is left out and the study is scored on the parts we could check. The study card says which. Second, anything that is not a peer-reviewed article is capped at 16/100 and carries a warning chip — so a conference abstract or a company press release can never outrank a peer-reviewed paper, no matter how good it looks.

We rank a rigorous null result — a good trial showing that something does not work — above an early positive finding. Someone deciding whether to buy a supplement is served by that, and the rigour is already counted by the design and journal components.

The score is computed from the published data alone and is reproducible: the same file always yields the same numbers.

See the whole rubric drawn out → — four charts covering all 28,580 studies: how the scores are spread and where the cap bites, which of the 20 components the library is strong and weak on, which subjects rest on stronger evidence, and what kinds of study each subject is actually built from.

What this library is — and isn't

This is a large sample of the Alzheimer's literature, not an exhaustive index of it. It holds 28,580 records, built mostly from automated pulls of Europe PMC (62.2% of the library) and OpenAlex (17.8%), plus smaller pulls from PubMed, Crossref and medRxiv. If a study, a drug, or a finding isn't here, that is not evidence it doesn't exist in the literature — it may simply not have been pulled in yet.

1,034 records (3.6% of the library) are not peer-reviewed — 962 of those are preprints posted before any journal review, and the rest are conference abstracts, regulatory notices and reports. Every study card on this page states its status plainly, and the score above is capped for anything that isn't a peer-reviewed article.

See the full, machine-readable breakdown of this library's coverage →

Newest studies, as a dated timeline →    Atom feed